Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nirmalya Dey"'
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42316 (2012)
Transforming growth factor-β (TGFβ) promotes glomerular hypertrophy and matrix expansion, leading to glomerulosclerosis. MicroRNAs are well suited to promote fibrosis because they can repress gene expression, which negatively regulate the fibrotic
Externí odkaz:
https://doaj.org/article/6e5a5fb3386b47208ca37b4c0d12d0b5
Autor:
Nirmalya Dey, Falguni Das, Nandini Ghosh-Choudhury, Chandi Charan Mandal, Dipen J Parekh, Karen Block, Balakuntalam S Kasinath, Hanna E Abboud, Goutam Ghosh Choudhury
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e37366 (2012)
Metastatic renal cancer manifests multiple signatures of gene expression. Deviation in expression of mature miRNAs has been linked to human cancers. Importance of miR-21 in renal cell carcinomas is proposed from profiling studies using tumor tissue s
Externí odkaz:
https://doaj.org/article/fecfa45e1eea4ab482d8511fbb874a17
Publikováno v:
Indian Journal of Pharmaceutical Sciences. 83
Favipiravir and remdesivir are investigational drugs for coronavirus disease 2019 that is caused by severe acute respiratory syndrome coronavirus 2. The active forms of these drugs are reported to target and inhibit viral RNA dependent RNA polymerase
Autor:
Falguni Das, Balakuntalam S. Kasinath, Amit Bera, Nandini Ghosh-Choudhury, Goutam Ghosh Choudhury, Nirmalya Dey
Publikováno v:
Cellular Signalling. 27:1276-1285
High glucose milieu inhibits PTEN expression to activate Akt kinase and induces glomerular mesangial cell hypertrophy and matrix protein expression in diabetic nephropathy. Specific mechanism by which high glucose inhibits PTEN expression is not clea
Autor:
Ajit Deka, Nirmalya Dey
Publikováno v:
Journal of Coatings Technology and Research. 10:305-315
The work presented in this article involves the study of rheometric profile of several rheological additives in two-component (2K) high build epoxy zinc phosphate primer and two-component high build aliphatic polyurethane topcoat. Viscosity profile a
Publikováno v:
Archives Of Phytopathology And Plant Protection. 45:1026-1038
Rice necrosis mosaic virus-inoculated jute plants looked more juvenile with enhanced leaf size than control ones. Such enlarged leaves and those from control ones were collected separately and extracted in chilled methanol. The crude tissue extract i
Autor:
Nandini Ghosh-Choudhury, Nirmalya Dey, Falguni Das, Goutam Ghosh Choudhury, Balachandar Venkatesan, Balakuntalam S. Kasinath
Publikováno v:
Cellular Signalling. 23:1311-1319
The Akt kinase signaling pathway is frequently deregulated in many human diseases including cancer, autoimmune disease and diabetes. In nephropathy, associated with diabetes, increased Akt signal transduction results in glomerular especially mesangia
Autor:
Xiaonan Li, Goutam Ghosh Choudhury, Falguni Das, Balakuntalam S. Kasinath, Nandini Ghosh-Choudhury, Nirmalya Dey, Balachandar Venkatesan, Jeffrey L. Barnes
Publikováno v:
Journal of Cellular Physiology. 225:27-41
Diabetic nephropathy manifests aberrant activation of TORC1, which senses key signals to modulate protein synthesis and renal hypertrophy. PRAS40 has recently been identified as a raptor-interacting protein and is a component and a constitutive inhib
Autor:
Nandini Ghosh-Choudhury, Falguni Das, Amit Bera, Balakuntalam S. Kasinath, Goutam Ghosh Choudhury, Nirmalya Dey
Publikováno v:
The Journal of biological chemistry. 291(28)
Elevated IGF-1/insulin-like growth factor-1 receptor (IGF-1R) autocrine/paracrine signaling in patients with renal cell carcinoma is associated with poor prognosis of the disease independent of their von Hippel-Lindau (VHL) status. Increased expressi
Autor:
Amit Bera, Falguni Das, Goutam Ghosh Choudhury, Balakuntalam S. Kasinath, Meenalakshmi M. Mariappan, Nandini Ghosh-Choudhury, Nirmalya Dey
High glucose-induced Akt acts as a signaling hub for mesangial cell hypertrophy and matrix expansion, which are recognized as cardinal signatures for the development of diabetic nephropathy. How mesangial cells sustain the activated state of Akt is n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238494dcff960e909cdc808c00960bbf
https://europepmc.org/articles/PMC4239622/
https://europepmc.org/articles/PMC4239622/