Genomic and transcriptomic characterization of delta SARS-CoV-2 infection in free-ranging white-tailed deer ( Odocoileus virginianus ).

Autor: Kotwa JD; Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada., Lobb B; Department of Biology, University of Waterloo, Waterloo, ON N2L 3G1, Canada., Massé A; Ministère de l'Environnement, de la Lutte contre les changements climatiques, de la Faune et des Parcs, Québec City, QC G1S 4X4, Canada., Gagnier M; Ministère de l'Environnement, de la Lutte contre les changements climatiques, de la Faune et des Parcs, Québec City, QC G1S 4X4, Canada., Aftanas P; Shared Hospital Laboratory, Toronto, ON M4N 3M5, Canada., Banerjee A; Department of Biology, University of Waterloo, Waterloo, ON N2L 3G1, Canada.; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.; Department of Veterinary Microbiology, University of Saskatchewan, Saskatoon, SK S7N 5A2, Canada.; Department of Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A1, Canada.; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, Canada., Banete A; Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada., Blais-Savoie J; Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada., Bowman J; Wildlife Research and Monitoring Section, Ontario Ministry of Natural Resources and Forestry, Peterborough, ON K9J 8M5, Canada., Buchanan T; Wildlife Research and Monitoring Section, Ontario Ministry of Natural Resources and Forestry, Peterborough, ON K9J 8M5, Canada., Chee HY; Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.; Global Health Research Center and Division of Natural and Applied Sciences, Duke Kunshan University, Kunshan, Jiangsu 215316, China., Kruczkiewicz P; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, MB R3E 3M4, Canada., Nirmalarajah K; Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada., Soos C; Ecotoxicology and Wildlife Health Division, Environment and Climate Change Canada, Saskatoon, SK S7N 3H5, Canada.; Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada., Vernygora O; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, MB R3E 3M4, Canada., Yip L; Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada., Lindsay LR; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3L5, Canada., McGeer AJ; Department of Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A1, Canada.; Sinai Health System, Toronto, ON M5G 1X5, Canada., Maguire F; Faculty of Computer Science, Dalhousie University, Halifax, NS B3H 4R2, Canada.; Department of Community Health & Epidemiology, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 4R2, Canada.; Shared Hospital Laboratory, Toronto, ON M4N 3M5, Canada., Lung O; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, MB R3E 3M4, Canada.; Department of Biological Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada., Doxey AC; Department of Biology, University of Waterloo, Waterloo, ON N2L 3G1, Canada., Pickering B; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, MB R3E 3M4, Canada.; Department of Veterinary Microbiology and Preventative Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB R3T 2N2, Canada., Mubareka S; Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.; Department of Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A1, Canada.

Publikováno v: IScience [iScience] 2023 Oct 24; Vol. 26 (11), pp. 108319. Date of Electronic Publication: 2023 Oct 24 (Print Publication: 2023).

Sensitivity to Neutralizing Antibodies and Resistance to Type I Interferons in SARS-CoV-2 R.1 Lineage Variants, Canada.

Autor: Jacob RA, Zhang A, Ajoge HO, D'Agostino MR, Nirmalarajah K, Shigayeva A, Demian WL, Baker SJC, Derakhshani H, Rossi L, Nasir JA, Panousis EM, Draia AN, Vermeiren C, Gilchrist J, Smieja N, Bulir D, Smieja M, Surette MG, McArthur AG, McGeer AJ, Mubareka S, Banerjee A, Miller MS, Mossman K

Publikováno v: Emerging infectious diseases [Emerg Infect Dis] 2023 Jul; Vol. 29 (7), pp. 1386-1396. Date of Electronic Publication: 2023 Jun 12.

Publisher Correction: Divergent SARS-CoV-2 variant emerges in white-tailed deer with deer-to-human transmission.

Autor: Pickering B; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada. bradley.pickering@canada.ca.; Department of Veterinary Microbiology and Preventative Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA. bradley.pickering@canada.ca.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada. bradley.pickering@canada.ca., Lung O; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada.; Department of Biological Sciences, University of Manitoba, Winnipeg, Manitoba, Canada., Maguire F; Faculty of Computer Science, Dalhousie University, Halifax, Nova Scotia, Canada.; Department of Community Health & Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.; Shared Hospital Laboratory, Toronto, Ontario, Canada.; Sunnybrook Research Institute, Toronto, Ontario, Canada., Kruczkiewicz P; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada., Kotwa JD; Sunnybrook Research Institute, Toronto, Ontario, Canada., Buchanan T; Wildlife Research and Monitoring Section, Ontario Ministry of Natural Resources and Forestry, Peterborough, Ontario, Canada., Gagnier M; Ministère des Forêts, de la Faune et des Parcs, Quebec City, Quebec, Canada., Guthrie JL; Public Health Ontario, Toronto, Ontario, Canada.; Department of Microbiology & Immunology, Western University, London, Toronto, Ontario, Canada., Jardine CM; Canadian Wildlife Health Cooperative, Ontario-Nunavut, Department of Pathobiology, University of Guelph, Guelph, Ontario, Canada., Marchand-Austin A; Public Health Ontario, Toronto, Ontario, Canada., Massé A; Ministère des Forêts, de la Faune et des Parcs, Quebec City, Quebec, Canada., McClinchey H; Public Health, Health Protection and Surveillance Policy and Programs Branch, Ontario Ministry of Health, Toronto, Ontario, Canada., Nirmalarajah K; Sunnybrook Research Institute, Toronto, Ontario, Canada., Aftanas P; Shared Hospital Laboratory, Toronto, Ontario, Canada., Blais-Savoie J; Sunnybrook Research Institute, Toronto, Ontario, Canada., Chee HY; Sunnybrook Research Institute, Toronto, Ontario, Canada., Chien E; Sunnybrook Research Institute, Toronto, Ontario, Canada., Yim W; Sunnybrook Research Institute, Toronto, Ontario, Canada., Banete A; Sunnybrook Research Institute, Toronto, Ontario, Canada., Griffin BD; Sunnybrook Research Institute, Toronto, Ontario, Canada., Yip L; Sunnybrook Research Institute, Toronto, Ontario, Canada., Goolia M; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada., Suderman M; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada., Pinette M; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada., Smith G; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada., Sullivan D; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada.; Department of Biological Sciences, University of Manitoba, Winnipeg, Manitoba, Canada., Rudar J; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada., Vernygora O; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada., Adey E; Wildlife Research and Monitoring Section, Ontario Ministry of Natural Resources and Forestry, Peterborough, Ontario, Canada., Nebroski M; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada., Goyette G; Centre de Recherche du CHUM, Montréal, Quebec, Canada., Finzi A; Centre de Recherche du CHUM, Montréal, Quebec, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, Quebec, Canada., Laroche G; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity, and Inflammation, University of Ottawa, Ottawa, Ontario, Canada., Ariana A; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity, and Inflammation, University of Ottawa, Ottawa, Ontario, Canada., Vahkal B; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity, and Inflammation, University of Ottawa, Ottawa, Ontario, Canada., Côté M; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity, and Inflammation, University of Ottawa, Ottawa, Ontario, Canada., McGeer AJ; Sinai Health System, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Nituch L; Wildlife Research and Monitoring Section, Ontario Ministry of Natural Resources and Forestry, Peterborough, Ontario, Canada., Mubareka S; Sunnybrook Research Institute, Toronto, Ontario, Canada. samira.mubareka@sunnybrook.ca.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. samira.mubareka@sunnybrook.ca., Bowman J; Wildlife Research and Monitoring Section, Ontario Ministry of Natural Resources and Forestry, Peterborough, Ontario, Canada. jeff.bowman@ontario.ca.; Environmental and Life Sciences Graduate Program, Trent University, Peterborough, Ontario, Canada. jeff.bowman@ontario.ca.

Publikováno v: Nature microbiology [Nat Microbiol] 2023 Jan; Vol. 8 (1), pp. 188.

Immunogenicity of convalescent and vaccinated sera against clinical isolates of ancestral SARS-CoV-2, Beta, Delta, and Omicron variants.

Autor: Banerjee A; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.; Department of Veterinary Microbiology, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada.; Department of Biology, University of Waterloo, Waterloo, ON N2L 3G1, Canada., Lew J; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada., Kroeker A; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada., Baid K; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada., Aftanas P; Shared Hospital Laboratory, Toronto, ON M4N 3M5, Canada., Nirmalarajah K; Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada., Maguire F; Faculty of Computer Science, Dalhousie University, Halifax, NS B3H 4R2, Canada., Kozak R; Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada., McDonald R; Roy Romanow Provincial Laboratory, Saskatchewan Health Authority, Regina, SK S4S 0A4, Canada., Lang A; Roy Romanow Provincial Laboratory, Saskatchewan Health Authority, Regina, SK S4S 0A4, Canada.; College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Gerdts V; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.; Department of Veterinary Microbiology, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada., Straus SE; Department of Medicine, University of Toronto, Toronto, ON M5S 3H2, Canada.; Unity Health, Toronto, ON M5B 1W8, Canada., Gilbert L; Sinai Health System, Toronto, ON M5G 1X5, Canada., Li AX; Sinai Health System, Toronto, ON M5G 1X5, Canada., Mozafarihashjin M; Sinai Health System, Toronto, ON M5G 1X5, Canada., Walmsley S; University Health Network, Toronto, ON M5G 2C4, Canada., Gingras AC; Sinai Health System, Toronto, ON M5G 1X5, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada., Wrana JL; Sinai Health System, Toronto, ON M5G 1X5, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada., Mazzulli T; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada.; Sinai Health System, Toronto, ON M5G 1X5, Canada.; University Health Network, Toronto, ON M5G 2C4, Canada., Colwill K; Sinai Health System, Toronto, ON M5G 1X5, Canada., McGeer AJ; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada.; Sinai Health System, Toronto, ON M5G 1X5, Canada.; Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5S 1A1, Canada., Mubareka S; Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada., Falzarano D; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.; Department of Veterinary Microbiology, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada.

Publikováno v: Med (New York, N.Y.) [Med (N Y)] 2022 Jun 10; Vol. 3 (6), pp. 422-432.e3. Date of Electronic Publication: 2022 Apr 14.

Limited Short-Term Evolution of SARS-CoV-2 RNA-Dependent RNA Polymerase under Remdesivir Exposure in Upper Respiratory Compartments.

Autor: Novitsky, Vladimir¹ (AUTHOR) vnovitsky@lifespan.org, Beckwith, Curt G.¹ (AUTHOR) cbeckwith@lifespan.org, Carpenter-Azevedo, Kristin² (AUTHOR) kristin.azevedo@health.ri.gov, Shin, Jimin³ (AUTHOR) jimin_shin@alumni.brown.edu, Hague, Joel¹ (AUTHOR) jhague@lifespan.org, Sam, Soya¹ (AUTHOR) ssam2@lifespan.org, Steingrimsson, Jon⁴ (AUTHOR) jon_steingrimsson@brown.edu, Huard, Richard C.² (AUTHOR) richard.huard@health.ri.gov, Lethbridge, Kevin⁵ (AUTHOR) klethbridge@lifespan.org, Sahu, Sujata⁶ (AUTHOR) sujata.sahu@lifespan.org, Rapoza, Kim⁶ (AUTHOR) krapoza1@lifespan.org, Chandran, Karen⁶ (AUTHOR) kchandran@lifespan.org, Bazerman, Lauri⁶ (AUTHOR) lbazerman@lifespan.org, Hipolito, Evelyn⁵ (AUTHOR) ehipolito@lifespan.org, Diaz, Isabella⁵ (AUTHOR) idiaz2@lifespan.org, Carnevale, Daniella⁵ (AUTHOR) dcarnevale3@lifespan.org, Guang, August⁷ (AUTHOR) august_guang@brown.edu, Gillani, Fizza^1,5 (AUTHOR) fgillani@lifespan.org, Caliendo, Angela M.¹ (AUTHOR) angela.caliendo@brownphysicians.org, Kantor, Rami¹ (AUTHOR) rkantor@brown.edu

Publikováno v: Viruses (1999-4915). Oct2024, Vol. 16 Issue 10, p1511. 14p.