Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Nirmala SundarRaj"'
Publikováno v:
Journal of Biological Chemistry. 279:24307-24312
Cellular responses to wounding have often been studied at a molecular level after disrupting cell layers by mechanical means. This invariably results in damage to cells at the edges of the wounds, which has been suggested to be instrumental for initi
Autor:
Jane R. Dunlevy, John R. Hassell, Bridgette L. Berryhill, Nirmala SundarRaj, Jean-Paul Vergnes
Publikováno v:
Genomics. 62:519-524
The cornea contains, as a major element, a transparent stroma produced and maintained by keratocytes (fibroblasts). Through molecular biology studies using cultured human corneal fibroblasts, a cDNA that was shown to be novel was isolated and sequenc
Autor:
Jody A. Summers Rada, John R. Hassell, Nirmala SundarRaj, Sonali Sundarraj, Robb Belak, Dana Fite, Shonosuke Okamoto
Publikováno v:
Experimental Eye Research. 67:433-442
Proteoglycan distribution during corneal stromal healing in growing corneas of young chicks were histologically and immunohistochemically analysed. Single linear incisions to produce partial-thickness wounds were made in the corneas of 5 day old chic
This study explored the efficacy of optical coherence tomography (OCT) as a high-resolution, noncontact method for imaging the palisades of Vogt by correlating OCT and confocal microscopy images.Human limbal rims were acquired and imaged with OCT and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab5346098a5536b85ddc043b65e848a
https://europepmc.org/articles/PMC3339911/
https://europepmc.org/articles/PMC3339911/
Publikováno v:
Investigative ophthalmologyvisual science. 52(12)
The cornea is a transparent avascular refractive structure consisting of three tissue layers, epithelium, stroma, and endothelium. A well-organized extracellular matrix (ECM) containing densely packed and regularly spaced thin collagen fibrils of uni
Autor:
Hidetaka Hara, Danny S. Roh, Jordan Piluek, Suyapa Ball, Yoshiaki Mizuguchi, David K. C. Cooper, Naoko Koike, Kumiko Isse, Carol Phelps, Cassandra Long, James L. Funderburgh, David Ayares, Nirmala SundarRaj
Although corneal transplantation is readily available in the United States and certain other regions of the developed world, the worldwide need for human donor corneas far exceeds the supply.1 The shortage is particularly severe in Asia.1,2 Furthermo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872654003aff25278ffeb990b29e7993
https://europepmc.org/articles/PMC3176056/
https://europepmc.org/articles/PMC3176056/
Publikováno v:
Investigative ophthalmologyvisual science. 49(1)
Purpose The authors' previous study showed that the expression of a Rho-associated serine/threonine kinase (ROCK) is regulated during cell cycle progression in corneal epithelial cells. The present study was conducted to determine whether and how Rho
Publikováno v:
The Journal of biological chemistry. 283(1)
Myocilin is a gene linked to the most common form of glaucoma, a major blinding disease. The trabecular meshwork (TM), a specialized eye tissue, is believed to be involved, at least in part, in the development of glaucoma. The myocilin expression is
Autor:
E. Helene Sage, Bruce L. Patton, Dimitri T. Azar, M. Cristina Kenney, Nirmala SundarRaj, Rupert Timpl, Ismo Virtanen, Takako Sasaki, Lydia Sorokin, Yoshifumi Ninomiya, Manuel Koch, Andrea Kabosova, Jonathan C.R. Jones, Gregory A. Bannikov, Mats Paulsson, Reza F. Ghohestani, Tung-Tien Sun, Kevin P. Campbell, Marie-France Steiner-Champliaud, Madeleine Durbeej, Alexander V. Ljubimov, Yoshikazu Sado
PURPOSE. Adult human corneal epithelial basement membrane ( EBM) and Descemet's membrane ( DM) components exhibit heterogeneous distribution. The purpose of the study was to identify changes of these components during postnatal corneal development. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f855c497e0b7009899771a456048d8
https://europepmc.org/articles/PMC2151758/
https://europepmc.org/articles/PMC2151758/
Publikováno v:
Cell motility and the cytoskeleton. 64(4)
Using an established corneal stromal cell differentiation model, we manipulated a-smooth muscle actin (a-SMA) protein expression levels in fibroblasts by treating them with TGF-b1, bFGF, TGF-b type I receptor inhibitor (SB-431542), and siRNA against