Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nirmala Padmanabhan"'
Autor:
Nicolas Chofflet, Yusuke Naito, Anthony John Pastore, Nirmala Padmanabhan, Phuong Trang Nguyen, Christian Poitras, Benjamin Feller, Nayoung Yi, Jeremie Van Prooijen, Husam Khaled, Benoit Coulombe, Steven J. Clapcote, Steve Bourgault, Tabrez J. Siddiqui, Gabby Rudenko, Hideto Takahashi
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
The prevailing model behind synapse development and specificity is that a multitude of adhesion molecules engage in transsynaptic interactions to induce pre- and postsynaptic assembly. How these extracellular interactions translate into intracellular
Externí odkaz:
https://doaj.org/article/b0e5ea6d61414d33a1c87b6f1bb93555
Autor:
Claire Bomkamp, Nirmala Padmanabhan, Benyamin Karimi, Yuan Ge, Jesse T. Chao, Christopher J. R. Loewen, Tabrez J. Siddiqui, Ann Marie Craig
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 11 (2019)
Formation of synapses between neurons depends in part on binding between axonal and dendritic cell surface synaptic organizing proteins, which recruit components of the developing presynaptic and postsynaptic specializations. One of these presynaptic
Externí odkaz:
https://doaj.org/article/a21c259f7a744c2e80735e08d29aee32
Autor:
Gilbert J. Kirouac, Samuel Booth, Shreya H. Dhume, Jeremy W. Chopek, Prabhisha Silwal, Nazmeena Zahra, Michael F. Jackson, Tabrez J. Siddiqui, Nirmala Padmanabhan, Ji Hyun Ko, Dali Zhang, Benyamin Karimi
Publikováno v:
Molecular Psychiatry. 26:6912-6925
Reduced activity of the mediodorsal thalamus (MD) and abnormal functional connectivity of the MD with the prefrontal cortex (PFC) cause cognitive deficits in schizophrenia. However, the molecular basis of MD hypofunction in schizophrenia is not known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::216d54c6e34e978e14760422a2d202e4
https://doi.org/10.1038/s41380-021-01146-6
https://doi.org/10.1038/s41380-021-01146-6
Publikováno v:
Neuron. 109:1248-1250
Competition between active and inactive synapses sculpts neuronal networks by activity-dependent loss of inactive connections, the mechanisms for which are poorly understood. In this issue of Neuron, Yasuda et al. (2021) demonstrate that JAK2-STAT1 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b0395d3086b19a63d18a404251cf1f5
https://doi.org/10.1016/j.neuron.2021.03.037
https://doi.org/10.1016/j.neuron.2021.03.037
Autor:
Benyamin, Karimi, Prabhisha, Silwal, Samuel, Booth, Nirmala, Padmanabhan, Shreya H, Dhume, Dali, Zhang, Nazmeena, Zahra, Michael F, Jackson, Gilbert J, Kirouac, Ji Hyun, Ko, Jeremy W, Chopek, Tabrez J, Siddiqui
Publikováno v:
Molecular psychiatry. 26(11)
Reduced activity of the mediodorsal thalamus (MD) and abnormal functional connectivity of the MD with the prefrontal cortex (PFC) cause cognitive deficits in schizophrenia. However, the molecular basis of MD hypofunction in schizophrenia is not known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e970e4f2e97c09f2bc6d3c3139c9bb1
https://pubmed.ncbi.nlm.nih.gov/33981006
https://pubmed.ncbi.nlm.nih.gov/33981006
Autor:
Tabrez J. Siddiqui, Nirmala Padmanabhan, Ann Marie Craig, Chi Zhang, Raunak Sinha, Fred Rieke, Julie Wallin, Rachel O.L. Wong, Mrinalini Hoon, Benyamin Karimi
Publikováno v:
Neuron. 105(6)
Summary LRRTM4 is a transsynaptic adhesion protein regulating glutamatergic synapse assembly on dendrites of central neurons. In the mouse retina, we find that LRRTM4 is enriched at GABAergic synapses on axon terminals of rod bipolar cells (RBCs). Kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4c1353d96fe030e170a155596fe9e7
https://pubmed.ncbi.nlm.nih.gov/32191854
https://pubmed.ncbi.nlm.nih.gov/32191854
Autor:
Nazmeena Zahra, Nirmala Padmanabhan, Shreya H. Dhume, Tabrez J. Siddiqui, Claire Bomkamp, Benyamin Karimi, Kevin Champagne-Jorgensen, Chetan S. Patil, Peng Zhang, Michael F. Jackson, Reiko T. Roppongi, Prabhisha Silwal, Rebecca E. Twilley
Publikováno v:
Neuron. 106:701
Presynaptic neurexins (Nrxs) and type IIa receptor-type protein tyrosine phosphatases (RPTPs) organize synapses through a network of postsynaptic ligands. We show that leucine-rich-repeat transmembrane neuronal proteins (LRRTMs) differentially engage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26079c5ef94eca13e3d08f2c9dd7829f
https://doi.org/10.1016/j.neuron.2020.05.003
https://doi.org/10.1016/j.neuron.2020.05.003
Autor:
Chetan S. Patil, Nazmeena Zahra, Prabhisha Silwal, Nirmala Padmanabhan, Michael F. Jackson, Tomoaki Shirao, Tabrez J. Siddiqui, Shreya H. Dhume, Kevin Champagne-Jorgensen, Reiko T. Roppongi
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 93:1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6f494de7650b8a5378bd34f264b32cd
https://doi.org/10.1254/jpssuppl.93.0_1-p-001
https://doi.org/10.1254/jpssuppl.93.0_1-p-001
Autor:
Sai T. Dharwada, Cayetana Schluter, Catherine Choi, Lauren E. Dalton, Björn D. M. Bean, Michael Davey, Elizabeth Conibear, Nirmala Padmanabhan
Publikováno v:
Traffic (Copenhagen, Denmark). 19(4)
The polytopic yeast protein Chs3 (chitin synthase III) relies on a dedicated membrane-localized chaperone, Chs7, for its folding and expression at the cell surface. In the absence of Chs7, Chs3 forms high molecular weight aggregates and is retained i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2daf21daf3cff049026decbbb38618c5
https://pubmed.ncbi.nlm.nih.gov/29405545
https://pubmed.ncbi.nlm.nih.gov/29405545
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1538
This protocol describes an in situ protein-protein interaction assay between tagged recombinant proteins and cell-surface expressed synaptic proteins. The assay is arguably more sensitive than other traditional protein binding assays such as co-immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d5f82b3012b9103ef2877d4d9fed3f2
https://pubmed.ncbi.nlm.nih.gov/27943185
https://pubmed.ncbi.nlm.nih.gov/27943185