Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nirmala Karunakaran Nancy"'
Publikováno v:
Journal of Pediatric Hematology/Oncology. 40:e1-e8
NOTCH1/FBXW7 mutations trigger oncogenic NOTCH1 signaling and its downstream target genes play crucial roles in the molecular pathogenesis of T-cell acute lymphoblastic leukemia (T-ALL). In the present study, NOTCH1 and FBXW7 mutations were studied i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6fa9f73917abf715f9a5dbcf79921ec
https://doi.org/10.1097/mph.0000000000001006
https://doi.org/10.1097/mph.0000000000001006
Autor:
Natarajan Sudhakar, Nirmala Karunakaran Nancy, Thangarajan Rajkumar, Kamalalayam Raghavan Rajalekshmy
Publikováno v:
Blood research
Background This study characterized clonal IG heavy V-D-J (IGH) gene rearrangements in South Indian patients with precursor B-cell acute lymphoblastic leukemia (precursor B-ALL) and identified age-related predominance in VDJ rearrangements. Methods I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a1b047c87fc6d182f4983751b7867f
https://pubmed.ncbi.nlm.nih.gov/28401103
https://pubmed.ncbi.nlm.nih.gov/28401103
Autor:
Natarajan, Sudhakar, Nirmala Karunakaran, Nancy, Kamalalayam Raghavan, Rajalekshmy, Thangarajan, Rajkumar
Publikováno v:
Iranian journal of immunology : IJI. 6(3)
Precursor B-Acute Lymphoblastic Leukemia (precursor B-ALL) occurs due to the uncontrolled proliferation of B-lymphoid precursors arrested at a particular stage of B-cell development. Precursor-B-ALL is classified mainly into pro-B-ALL, common-ALL and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ef6771afec924412d8befb1c3eb9806
https://pubmed.ncbi.nlm.nih.gov/19801787
https://pubmed.ncbi.nlm.nih.gov/19801787
Autor:
Rajaraman Swaminathan, Mani Samson, Thangarajan Rajkumar, Urmila Mahji, Nirmala Karunakaran Nancy, Ranganathan Rama, V Sridevi
Publikováno v:
Breast cancer research and treatment. 112(1)
The breast cancer incidence has been increasing in the south Indian women. A case (n=250)-control (n=500) study was undertaken to investigate the role of Single Nucleotide Polymorphisms (SNP's) in GSTM1 (Present/Null); GSTP1 (Ile105Val), p53 (Arg72Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73656521cdddaee15aff7d6607748221
https://pubmed.ncbi.nlm.nih.gov/18058229
https://pubmed.ncbi.nlm.nih.gov/18058229
Autor:
Kamalalayam Raghavan Rajalekshmy, Thangarajan Rajkumar, Nirmala Karunakaran Nancy, Natarajan Sudhakar, Ganapathi Ramanan
Publikováno v:
American journal of hematology. 82(3)
Clonal T-cell receptor (TCR) gamma and delta gene rearrangements were studied in 40 T-ALL cases (pediatrics, 29; adults, 11) using PCR with homo-heteroduplex analysis. At least one clonal TCRG or TCRD rearrangement was detected in 34 (85%) cases. TCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0086764811c7430a19ffa5b3ff8dd8ae
https://pubmed.ncbi.nlm.nih.gov/17133429
https://pubmed.ncbi.nlm.nih.gov/17133429
Autor:
Thangarajan, Rajkumar, Nagasamy, Soumittra, Nirmala Karunakaran, Nancy, Rajaraman, Swaminathan, Veluswami, Sridevi, Vishwanathan, Shanta
Publikováno v:
Asian Pacific journal of cancer prevention : APJCP. 4(3)
Cancer of the breast is the second most common cancer seen among Indian women. This study describes the use of DHPLC for mutation analysis for BRCA1, BRCA2 and CHEK2 (1100delC) in 22 patients with a family history of breast and/or ovarian cancer and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2594a5808543bbac62dd03781d466e2
https://pubmed.ncbi.nlm.nih.gov/14507240
https://pubmed.ncbi.nlm.nih.gov/14507240