Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Niren Patel"'
Autor:
Kyle Kidwell, Camila Albo, Michael Pope, Latanya Bowman, Hongyan Xu, Leigh Wells, Nadine Barrett, Niren Patel, Amy Allison, Abdullah Kutlar
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247324 (2021)
Vaso-occlusive episodes (VOEs) are a hallmark of sickle cell disease (SCD), and account for >90% of health care encounters for this patient population. The Cooperative Study of Sickle Cell Disease, a large study enrolling >3000 patients, showed that
Externí odkaz:
https://doaj.org/article/bd5590f0546b4e5d9da9945062d7b3cd
Autor:
Xingguo Zhu, Tianxiang Hu, Meng Hsuan Ho, Yongchao Wang, Miao Yu, Niren Patel, Wenhu Pi, Jeong-Hyeon Choi, Hongyan Xu, Vadivel Ganapathy, Ferdane Kutlar, Abdullah Kutlar, Dorothy Tuan
Publikováno v:
Haematologica, Vol 102, Iss 12 (2017)
Hydroxyurea (HU), the first of two drugs approved by the US Food and Drug Administration for treating patients with sickle cell disease (SCD), produces anti-sickling effect by re-activating fetal γ-globin gene to enhance production of fetal hemoglob
Externí odkaz:
https://doaj.org/article/53eaa618682545f998578fcfc3dd9fdc
Publikováno v:
Blood. 140:5414-5415
Publikováno v:
Point of Care: The Journal of Near-Patient Testing & Technology. 19:84-94
Autor:
Abdullah Kutlar, Pritam Bora, Abhishek A. Mangaonkar, Leigh Wells, Latanya Bowman, Niren Patel, Nadine Barrett, James Son, Fahim Thawer, Grace Jung, Hongyan Xu, Germame Ajebo, Betsy Clair, Elizabeta Nemeth
Publikováno v:
British Journal of Haematology. 189:1204-1209
Sickle cell disease (SCD) has a distinct pattern of transfusional iron overload (IO) when compared to transfusion-dependent β-thalassaemia major (TDT). We conducted a single institution prospective study to evaluate plasma biomarkers of iron regulat
Autor:
Hongyan Xu, Pritam Bora, Camila Albo, Latanya Bowman, Kyle Michael Kidwell, Michael Pope, Leigh Wells, Sabine Fields, Niren Patel, Abdullah Kutlar, Nadine Barrett, Sanjiv Kumar
Publikováno v:
European journal of haematologyREFERENCES. 105(4)
Objectives In this study, we investigated the evolution of chronic pain in sickle cell patients (SCD) as an age-dependent phenomenon and studied the frequency of vaso-occlusive episode frequency, opioid use, quantitative sensory testing (QST), and bi
Autor:
Vadivel Ganapathy, Hongyan Xu, Wenhu Pi, Yongchao Wang, Meng Hsuan Ho, Abdullah Kutlar, Ferdane Kutlar, Xingguo Zhu, Dorothy Tuan, Jeong Hyeon Choi, Tianxiang Hu, Niren Patel, Miao Yu
Publikováno v:
Haematologica
Hydroxyurea (HU), the first of two drugs approved by the US Food and Drug Administration for treating patients with sickle cell disease (SCD), produces anti-sickling effect by re-activating fetal γ-globin gene to enhance production of fetal hemoglob
Autor:
Latanya Bowman, Abdullah Kutlar, Steffen E. Meiler, Ryan A. Harris, Daniel Adamkiewicz, Jennifer S. Pollock, David M. Pollock, Niren Patel, Hongyan Xu, Leigh Wells
Publikováno v:
Blood. 136:25-26
Endothelin-1 (ET1) is a potent vasoconstrictor, mitogen, proinflammatory mediator, and a mediator of nociception, whose synthesis is increased by hypoxia, ischemia, shear stress, oxidative stress and reduced nitric oxide (NO) bioavailability, all of
Autor:
Janet L. Kwiatkowski, Lori Luchtman-Jones, Linda B. Piller, Jennifer A. Rothman, Abdullah Kutlar, R. Clark Brown, Theodosia A. Kalfa, Carla W. Roberts, William H. Schultz, Nicole A. Mortier, Robert J. Adams, Alexis A. Thompson, William Owen, Beng Fuh, Margaret T. Lee, Jamie L. Coleman, Judy Luden, Alex George, Donna R. Roberts, John C. Wood, Kerri Nottage, Ofelia A. Alvarez, Sharada A. Sarnaik, Melanie J. Bonner, Susan E. Stuber, Lee Hilliard, Hamayun Imran, Stephen C. Nelson, Sherron M. Jackson, Sara L. Pressel, Banu Aygun, Matthew M. Heeney, Melissa Rhodes, Connie M. Piccone, Naomi L.C. Luban, Zora R. Rogers, Scott T. Miller, Peng Wei, Kathleen J. Helton, Cynthia Gauger, Isaac Odame, Barry R. Davis, Russell E. Ware, Alan R. Cohen, Niren Patel
Publikováno v:
Lancet (London, England)
Summary Background For children with sickle cell anaemia and high transcranial doppler (TCD) flow velocities, regular blood transfusions can effectively prevent primary stroke, but must be continued indefinitely. The efficacy of hydroxycarbamide (hyd
Publikováno v:
Blood. 134:2258-2258
Background: Lung capillary barrier dysfunction is common to all causes of acute chest syndrome (ACS), a leading cause of morbidity and mortality in individuals with sickle cell disease (SCD). Our published data (Haematologica 2017, 102, e26-e29) demo