Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Nirav M. Amin"'
Autor:
Florian Brandes, Melanie Borrmann, Dominik Buschmann, Agnes S. Meidert, Marlene Reithmair, Markus Langkamp, Lutz Pridzun, Benedikt Kirchner, Jean-Noël Billaud, Nirav M. Amin, Joseph C. Pearson, Matthias Klein, Daniela Hauer, Clarissa Gevargez Zoubalan, Anja Lindemann, Alexander Choukér, Thomas W. Felbinger, Ortrud K. Steinlein, Michael W. Pfaffl, Ines Kaufmann, Gustav Schelling
Publikováno v:
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-22 (2021)
Abstract Background Progranulin is a widely expressed pleiotropic growth factor with a central regulatory effect during the early immune response in sepsis. Progranulin signaling has not been systematically studied and compared between sepsis, commun
Externí odkaz:
https://doaj.org/article/382b9dcb011c432dbd6249d8b5d66a74
Autor:
Nanette Nascone-Yoder, Michael K. Dush, Nirav M. Amin, Kristen Bagley, Jeffrey A. Yoder, Brent H. Wyatt, Dustin J. Wcisel
Publikováno v:
Development
The morphogenesis of left-right (LR) asymmetry is a crucial phase of organogenesis. In the digestive tract, the development of anatomical asymmetry is first evident in the leftward curvature of the stomach. To elucidate the molecular events that shap
Autor:
Zhiyu Liu, Herong Shi, Lindsey C Szymczak, Taner Aydin, Sijung Yun, Katharine Constas, Arielle Schaeffer, Sinthu Ranjan, Saad Kubba, Emad Alam, Devin E McMahon, Jingpeng He, Neta Shwartz, Chenxi Tian, Yevgeniy Plavskin, Amanda Lindy, Nimra Amir Dad, Sunny Sheth, Nirav M Amin, Stephanie Zimmerman, Dennis Liu, Erich M Schwarz, Harold Smith, Michael W Krause, Jun Liu
Publikováno v:
PLoS Genetics, Vol 11, Iss 5, p e1005221 (2015)
Bone morphogenetic proteins (BMPs) belong to the transforming growth factor β (TGFβ) superfamily of secreted molecules. BMPs play essential roles in multiple developmental and homeostatic processes in metazoans. Malfunction of the BMP pathway can c
Externí odkaz:
https://doaj.org/article/2cdd01aad6384a788b2ff6e185ab57fd
Publikováno v:
Developmental Biology. 439:80-91
Internal organs exhibit left-right asymmetric sizes, shapes and anatomical positions, but how these different lateralities develop is poorly understood. Here we use the experimentally tractable Xenopus model to uncover the morphogenetic events that d
Publikováno v:
Cold Spring Harbor protocols. 2019(6)
Analysis of the molecular mechanisms driving cell specification, differentiation, and other cellular processes can be difficult due to the heterogeneity of tissues and organs. Therefore, it is critical to isolate pure cell populations in order to pro
Publikováno v:
Developmental Dynamics. 243:948-956
Background: The zinc-finger transcription factor CASZ1 is required for differentiation of a distinct population of cardiomyocytes during development. However, expression of Casz1 mRNA is detected throughout the developing heart, suggesting the spatia
Publikováno v:
Developmental Biology. 389:137-148
The proper formation and function of an organ is dependent on the specification and integration of multiple cell types and tissues. An example of this is the Caenorhabditis elegans hermaphrodite egg-laying system, which requires coordination between
Autor:
Adam Davis, Caroline A. Johnson, H. Troy Ghashghaei, Nanette Nascone-Yoder, Kristen Bagley, Nirav M. Amin
Publikováno v:
Development (Cambridge, England). 144(8)
Left-right (LR) asymmetry is a fundamental feature of internal anatomy, yet the emergence of morphological asymmetry remains one of the least understood phases of organogenesis. Asymmetric rotation of the intestine is directed by forces outside the g
Publikováno v:
Cold Spring Harbor Protocols. 2019:pdb.prot098384
Analysis of the molecular mechanisms driving cell specification, differentiation, and other cellular processes can be difficult due to the heterogeneity of tissues and organs. Therefore, it is critical to isolate pure cell populations in order to pro
Publikováno v:
Mechanisms of Development. 125:451-461
Metazoan development proceeds primarily through the regulated expression of genes encoding transcription factors and components of cell signaling pathways. One way to decipher the complex developmental programs is to assemble the underlying gene regu