Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Nirasha Ramchurren"'
Autor:
Jeffrey R. Whiteaker, Lei Zhao, Regine M. Schoenherr, Dongqing Huang, Rachel A. Lundeen, Ulianna Voytovich, Jacob J. Kennedy, Richard G. Ivey, Chenwei Lin, Oscar D. Murillo, Travis D. Lorentzen, Simona Colantonio, Tessa W. Caceres, Rhonda R. Roberts, Joseph G. Knotts, Joshua J. Reading, Candice D. Perry, Christopher W. Richardson, Sandra S. Garcia-Buntley, William Bocik, Stephen M. Hewitt, Shrabanti Chowdhury, Jackie Vandermeer, Stephen D. Smith, Ajay K. Gopal, Nirasha Ramchurren, Steven P. Fling, Pei Wang, Amanda G. Paulovich
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionImmunotherapy is an effective treatment for a subset of cancer patients, and expanding the benefits of immunotherapy to all cancer patients will require predictive biomarkers of response and immune-related adverse events (irAEs). To suppo
Externí odkaz:
https://doaj.org/article/f412d3d737e448d4a0f5abc24df6f60b
Autor:
Tianying Su, George E. Duran, Alexa C. Kwang, Nirasha Ramchurren, Steven P. Fling, Youn H. Kim, Michael S. Khodadoust
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
The PD-1 inhibitor pembrolizumab is effective in treating Sézary syndrome, a leukemic variant of cutaneous T-cell lymphoma. Our purpose was to investigate the effects of pembrolizumab on healthy and malignant T cells in Sézary syndrome and to disco
Externí odkaz:
https://doaj.org/article/0320d623a02c4a77b456894a308c9fc9
Autor:
Darci Phillips, Magdalena Matusiak, Belén Rivero Gutierrez, Salil S. Bhate, Graham L. Barlow, Sizun Jiang, Janos Demeter, Kimberly S. Smythe, Robert H. Pierce, Steven P. Fling, Nirasha Ramchurren, Martin A. Cheever, Yury Goltsev, Robert B. West, Michael S. Khodadoust, Youn H. Kim, Christian M. Schürch, Garry P. Nolan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
PD-1 blockade is effective for only a subset of patients with cutaneous T cell lymphomas. Here, the authors report a spatial biomarker that uses immune and cancer cell topography to predict response to PD-1 blockade in this disease.
Externí odkaz:
https://doaj.org/article/185b95b3ae0241efb2f75ef0ed8fba8c
Autor:
Paul Nghiem, Suzanne Topalian, Steven Fling, Nirasha Ramchurren, Candice Church, Ulla Hansen, Amalie Bentzen, Sine Hadrup
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/7321b2f7239f4bc3a0055de1acc219a5
Autor:
Holden T Maecker, Lawrence Fong, Leonard D’Amico, Martin Cheever, Leonard Appleman, Steven P Fling, Nirasha Ramchurren, Russell Szmulewitz, Omer Kucuk, Paul Monk, Caroline Duault, Russell K Pachynski, Lauren Harshman, Rhonda L Bitting, Frederick Millard, John D Seigne, Bruce Hess, Andreanne Lacroix, Judith C Kaiser, Michel Morre, Anne Grégoire, Evan Y Yu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Externí odkaz:
https://doaj.org/article/54ac985393a84044a1fcf9109a088cab
Autor:
Natalie J. Miller, Candice D. Church, Steven P. Fling, Rima Kulikauskas, Nirasha Ramchurren, Michi M. Shinohara, Harriet M. Kluger, Shailender Bhatia, Lisa Lundgren, Martin A. Cheever, Suzanne L. Topalian, Paul Nghiem
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-9 (2018)
Abstract Background Merkel cell carcinoma (MCC) is an aggressive skin cancer that frequently responds to anti-PD-1 therapy. MCC is associated with sun exposure and, in 80% of cases, Merkel cell polyomavirus (MCPyV). MCPyV-specific T and B cell respon
Externí odkaz:
https://doaj.org/article/e8021ab7a1ff40af8dd91b15754b2650
Autor:
Nicolas A. Giraldo, Peter Nguyen, Elizabeth L. Engle, Genevieve J. Kaunitz, Tricia R. Cottrell, Sneha Berry, Benjamin Green, Abha Soni, Jonathan D. Cuda, Julie E. Stein, Joel C. Sunshine, Farah Succaria, Haiying Xu, Aleksandra Ogurtsova, Ludmila Danilova, Candice D. Church, Natalie J. Miller, Steve Fling, Lisa Lundgren, Nirasha Ramchurren, Jennifer H. Yearley, Evan J. Lipson, Mac Cheever, Robert A. Anders, Paul T. Nghiem, Suzanne L. Topalian, Janis M. Taube
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-11 (2018)
Abstract Background We recently reported a 56% objective response rate in patients with advanced Merkel cell carcinoma (MCC) receiving pembrolizumab. However, a biomarker predicting clinical response was not identified. Methods Pretreatment FFPE tumo
Externí odkaz:
https://doaj.org/article/76e43af2693646548cca3682365754c1
Autor:
Chihiro Morishima, Lawrence Fong, Holden Maecker, Leonard D’Amico, Steven Fling, Martin Cheever, Nirasha Ramchurren, Sean Bendall, Caroline Duault, Mina Pichavant, Bita Sahaf
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/6226d482a3804517bed24e45521f5742
Autor:
Brian D Hondowicz, Katharine V Schwedhelm, Arnold Kas, Michael A Tasch, Crystal Rawlings, Nirasha Ramchurren, Martin McIntosh, Leonard A D'Amico, Srinath Sanda, Nathan E Standifer, Jay Shendure, Brad Stone
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29949 (2012)
The identification of novel T cell antigens is central to basic and translational research in autoimmunity, tumor immunology, transplant immunology, and vaccine design for infectious disease. However, current methods for T cell antigen discovery are
Externí odkaz:
https://doaj.org/article/f2025b1ba27e4c41b1153450df9f697c
Autor:
Nirasha Ramchurren, Rachael Parks, Laura Islas, Steven Fling, Michael Khodadoust, Evan Newell, David Glass
Publikováno v:
Regular and Young Investigator Award Abstracts.