Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Niranjan B. Butchi"'
Autor:
Silvia Madeddu, Tyson A Woods, Piyali Mukherjee, Dan Sturdevant, Niranjan B Butchi, Karin E Peterson
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0127336 (2015)
The activation of astrocytes and microglia is often associated with diseases of the central nervous system (CNS). Understanding how activation alters the transcriptome of these cells may offer valuable insight regarding how activation of these cells
Externí odkaz:
https://doaj.org/article/8600668d650f4dbd80d57634c70c7762
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22454 (2011)
The functional role of murine TLR8 in the inflammatory response of the central nervous system (CNS) remains unclear. Murine TLR8 does not appear to respond to human TLR7/8 agonists, due to a five amino acid deletion in the ectodomain. However, recent
Externí odkaz:
https://doaj.org/article/075e0d24eae14d7b86346269b8df2755
Autor:
Stephen A. Stohlman, Shweta S. Puntambekar, Parul Kapil, Niranjan B. Butchi, Cornelia C. Bergmann, David R. Hinton
Publikováno v:
Journal of Virology
Myd88 signaling is critical to the control of numerous central nervous system (CNS) infections by promoting both innate and adaptive immune responses. Nevertheless, the extent to which Myd88 regulates type I interferon (IFN) versus proinflammatory fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0947bd3af237b9c731f31b7edcaa5e
https://doi.org/10.1128/jvi.01199-15
https://doi.org/10.1128/jvi.01199-15
Autor:
Ganes C. Sen, Cornelia C. Bergmann, David R. Hinton, Niranjan B. Butchi, Volker Fensterl, Stephen A. Stohlman, Parul Kapil
Publikováno v:
Journal of Virology
Type I interferons (IFN-α/β) limit viral dissemination prior to the emergence of adaptive immune responses through the concerted action of interferon-stimulated genes (ISGs). Although IFN-α/β induction by coronaviruses is modest, it effectively l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9469276a96e9687cf2e981a7f9338365
Autor:
Niranjan B. Butchi, Sonja M. Best, Karin E. Peterson, Timothy M. Morgan, David G. Baker, R. Travis Taylor, Piyali Mukherjee, Tyson A. Woods, Kirk J. Lubick, Piyanate Sunyakumthorn
Publikováno v:
Journal of General Virology. 94:336-347
Toll-like receptor 7 (TLR7) recognizes guanidine-rich viral ssRNA and is an important mediator of peripheral immune responses to several ssRNA viruses. However, the role that TLR7 plays in regulating the innate immune response to ssRNA virus infectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4f6706c3cd0b3b00596da2aca93d11
https://doi.org/10.1099/vir.0.043984-0
https://doi.org/10.1099/vir.0.043984-0
Publikováno v:
The American Journal of Pathology. 179:783-794
Toll-like receptors (TLRs) 7 and 9 recognize nucleic acid determinants from viruses and bacteria and elicit the production of type I interferons and proinflammatory cytokines. TLR7 and TLR9 are similar regarding localization and signal transduction m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e0a839dbbcc1d53ea2e0d6ab472f75
https://doi.org/10.1016/j.ajpath.2011.04.011
https://doi.org/10.1016/j.ajpath.2011.04.011
Publikováno v:
ResearcherID
Activation of astrocytes and microglia and the production of proinflammatory cytokines and chemokines are often associated with virus infection in the CNS as well as a number of neurological diseases of unknown etiology. These inflammatory responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0929e65fabd5703683af96c06732b9ab
https://doi.org/10.4049/jimmunol.180.11.7604
https://doi.org/10.4049/jimmunol.180.11.7604
Autor:
Shizuo Akira, S.S. Pourciau, Karin E. Peterson, Mohammed Khaleduzzaman, Timothy W. Morgan, Niranjan B. Butchi, David G. Baker, Min Du, Stephanie D Lewis
Publikováno v:
Journal of Neurovirology. 14:492-502
Toll-like receptor 7 (TLR7) recognizes guanidine-rich single-stranded (ss) viral RNA and is an important mediator of peripheral immune responses to several ssRNA viruses. However, the role that TLR7 plays in regulating the innate immune response to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53889ed17dfbba0add5edfcec956e76
https://doi.org/10.1080/13550280802345723
https://doi.org/10.1080/13550280802345723
Publikováno v:
Journal of Neurovirology. 13:384-388
In this study, the authors examined the role of bovine herpesvirus type 1 (BHV-1) Us9 in the anterograde transport of the virus from trigeminal ganglia (TG) to nose and eye upon reactivation from latency. During primary infection, both BHV-1 Us9-dele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ba79d4401f35ffb6aaa606665486cf
https://doi.org/10.1080/13550280701375433
https://doi.org/10.1080/13550280701375433
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22454 (2011)
PLoS ONE
PLoS ONE
The functional role of murine TLR8 in the inflammatory response of the central nervous system (CNS) remains unclear. Murine TLR8 does not appear to respond to human TLR7/8 agonists, due to a five amino acid deletion in the ectodomain. However, recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2379bd09e57aed609c452b665bf1fdb0
http://europepmc.org/articles/PMC3141064?pdf=render
http://europepmc.org/articles/PMC3141064?pdf=render