Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Niran, Hadad"'
Detecting the effect of genetic diversity on brain composition in an Alzheimer’s disease mouse model
Autor:
Brianna Gurdon, Sharon C. Yates, Gergely Csucs, Nicolaas E. Groeneboom, Niran Hadad, Maria Telpoukhovskaia, Andrew Ouellette, Tionna Ouellette, Kristen M. S. O’Connell, Surjeet Singh, Thomas J. Murdy, Erin Merchant, Ingvild Bjerke, Heidi Kleven, Ulrike Schlegel, Trygve B. Leergaard, Maja A. Puchades, Jan G. Bjaalie, Catherine C. Kaczorowski
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Alzheimer’s disease (AD) is broadly characterized by neurodegeneration, pathology accumulation, and cognitive decline. There is considerable variation in the progression of clinical symptoms and pathology in humans, highlighting the import
Externí odkaz:
https://doaj.org/article/3326d64ae7b146da806282ce29ff4520
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-18 (2019)
Abstract Background Alterations to cellular and molecular programs with brain aging result in cognitive impairment and susceptibility to neurodegenerative disease. Changes in DNA methylation patterns, an epigenetic modification required for various C
Externí odkaz:
https://doaj.org/article/63e1a0afff5b4799ad0eb10f2eaeecc0
Autor:
Shivani N Mann, Niran Hadad, Molly Nelson Holte, Alicia R Rothman, Roshini Sathiaseelan, Samim Ali Mondal, Martin-Paul Agbaga, Archana Unnikrishnan, Malayannan Subramaniam, John Hawse, Derek M Huffman, Willard M Freeman, Michael B Stout
Publikováno v:
eLife, Vol 9 (2020)
Metabolic dysfunction underlies several chronic diseases, many of which are exacerbated by obesity. Dietary interventions can reverse metabolic declines and slow aging, although compliance issues remain paramount. 17α-estradiol treatment improves me
Externí odkaz:
https://doaj.org/article/1b1546f66bc7437c80062d0bfab7f142
Autor:
Amy R. Dunn, Niran Hadad, Sarah M. Neuner, Ji-Gang Zhang, Vivek M. Philip, Logan Dumitrescu, Timothy J. Hohman, Jeremy H. Herskowitz, Kristen M. S. O’Connell, Catherine C. Kaczorowski
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Developing strategies to maintain cognitive health is critical to quality of life during aging. The basis of healthy cognitive aging is poorly understood; thus, it is difficult to predict who will have normal cognition later in life. Individuals may
Externí odkaz:
https://doaj.org/article/55c45b3c6f334db690a33914c1daf442
Autor:
Colleen A. Mangold, Benjamin Wronowski, Mei Du, Dustin R. Masser, Niran Hadad, Georgina V. Bixler, Robert M. Brucklacher, Matthew M. Ford, William E. Sonntag, Willard M. Freeman
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-19 (2017)
Abstract Background The necessity of including both males and females in molecular neuroscience research is now well understood. However, there is relatively limited basic biological data on brain sex differences across the lifespan despite the diffe
Externí odkaz:
https://doaj.org/article/8ff50482fdfc4d15be815b02c6ed9c50
Autor:
Sarah R. Ocañas, Victor A. Ansere, Kyla B. Tooley, Niran Hadad, Ana J. Chucair-Elliott, David R. Stanford, Shannon Rice, Benjamin Wronowski, Kevin D. Pham, Jessica M. Hoffman, Steven N. Austad, Michael B. Stout, Willard M. Freeman
Publikováno v:
Molecular Neurobiology. 59:4669-4702
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36764912db4661a717d62860b4f14a93
https://doi.org/10.1007/s12035-022-02860-0
https://doi.org/10.1007/s12035-022-02860-0
Autor:
Jaclyn M, Eissman, Logan, Dumitrescu, Emily R, Mahoney, Alexandra N, Smith, Shubhabrata, Mukherjee, Michael L, Lee, Phoebe, Scollard, Seo Eun, Choi, William S, Bush, Corinne D, Engelman, Qiongshi, Lu, David W, Fardo, Emily H, Trittschuh, Jesse, Mez, Catherine C, Kaczorowski, Hector, Hernandez Saucedo, Keith F, Widaman, Rachel F, Buckley, Michael J, Properzi, Elizabeth C, Mormino, Hyun Sik, Yang, Theresa M, Harrison, Trey, Hedden, Kwangsik, Nho, Shea J, Andrews, Douglas, Tommet, Niran, Hadad, R Elizabeth, Sanders, Douglas M, Ruderfer, Katherine A, Gifford, Xiaoyuan, Zhong, Neha S, Raghavan, Badri N, Vardarajan, Margaret A, Pericak-Vance, Lindsay A, Farrer, Li San, Wang, Carlos, Cruchaga, Gerard D, Schellenberg, Nancy J, Cox, Jonathan L, Haines, C Dirk, Keene, Andrew J, Saykin, Eric B, Larson, Reisa A, Sperling, Richard, Mayeux, Michael L, Cuccaro, David A, Bennett, Julie A, Schneider, Paul K, Crane, Angela L, Jefferson, Timothy J, Hohman
Publikováno v:
Brain. 145:2541-2554
Approximately 30% of elderly adults are cognitively unimpaired at time of death despite the presence of Alzheimer’s disease neuropathology at autopsy. Studying individuals who are resilient to the cognitive consequences of Alzheimer’s disease neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9063cca0ef4beb1fea1c62ef8ed6e8af
https://doi.org/10.1093/brain/awac177
https://doi.org/10.1093/brain/awac177
Detecting the effect of genetic diversity on brain composition in an Alzheimer’s disease mouse model
Autor:
Brianna Gurdon, Sharon C. Yates, Gergely Csucs, Nicolaas E. Groeneboom, Niran Hadad, Maria Telpoukhovskaia, Andrew Ouellette, Tionna Ouellette, Kristen O’Connell, Surjeet Singh, Tom Murdy, Erin Merchant, Ingvild Bjerke, Heidi Kleven, Ulrike Schlegel, Trygve B. Leergaard, Maja A. Puchades, Jan G. Bjaalie, Catherine C. Kaczorowski
Alzheimer’s disease (AD) is characterized by neurodegeneration, pathology accumulation, and progressive cognitive decline. There is significant variation in age at onset and severity of symptoms highlighting the importance of genetic diversity in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1d9dae52422b372cefc2560f6473c3a
https://doi.org/10.1101/2023.02.27.530226
https://doi.org/10.1101/2023.02.27.530226
Autor:
Catherine C. Kaczorowski, Surjeet Singh, Harpreet Kaur, Niran Hadad, Maria Telpoukhovskaia, Jigang Zhang, Vivek M. Philip, Kristen MS O'Connell, Zachary Levine, Amy R Dunn
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63d1eca8e10e2bb523b226a343fccbbb
https://doi.org/10.1002/alz.067225
https://doi.org/10.1002/alz.067225
Autor:
Mariah R Berchulski, Jonathan R Funke, Niran Hadad, Kristen MS O'Connell, Catherine C. Kaczorowski
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9095267a74a3cdb744504a7314e650c1
https://doi.org/10.1002/alz.068784
https://doi.org/10.1002/alz.068784