Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Niral B Gandhi"'
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78508 (2013)
CD4(+) T cells are essential to pathogenesis of ocular surface disease in dry eye. Two subtypes of CD4(+) T cells, Th1 and Th17 cells, function concurrently in dry eye to mediate disease. This occurs in spite of the cross-regulation of IFN-γ and IL-
Externí odkaz:
https://doaj.org/article/823b31a6a55b40b984ab4ee5f7e81fbd
Autor:
Xiaobo Zhang, Eugene A Volpe, Niral B Gandhi, Chris S Schaumburg, Karyn F Siemasko, Solherny B Pangelinan, Scott D Kelly, Adrian C Hayday, De-Quan Li, Michael E Stern, Jerry Y Niederkorn, Stephen C Pflugfelder, Cintia S De Paiva
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36822 (2012)
BACKGROUND:The conjunctiva contains a specialized population of lymphocytes that reside in the epithelium, named intraepithelial lymphocytes (IEL). METHODOLOGY/PRINCIPAL FINDINGS:Here we characterized the IEL population prior to and after experimenta
Externí odkaz:
https://doaj.org/article/431865b32c9f4602af63cf36f51c4908
Autor:
Cintia S De Paiva, Eugene A Volpe, Niral B Gandhi, Xiaobo Zhang, Xiaofen Zheng, John D Pitcher, William J Farley, Michael E Stern, Jerry Y Niederkorn, De-Quan Li, Richard A Flavell, Stephen C Pflugfelder
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29017 (2011)
BackgroundTGF-β is a pleiotropic cytokine that can have pro- or anti-inflammatory effects depending on the context. Elevated levels of bioactive TGF-β1 in tears and elevated TGF-β1mRNA transcripts in conjunctiva and minor salivary glands of human
Externí odkaz:
https://doaj.org/article/60dc5f26b15249c1a0229a4f9063c6a7
Autor:
Ping Wang, Charles J. Glueck, Parth Shah, Kailash Hemachandra, Domonique Smith, Niral B Gandhi
Publikováno v:
Blood Coagulation & Fibrinolysis. 26:736-742
In 1014 patients with thrombotic events, we determined how often treatable high serum homocysteine alone, or in concert with five other thrombophilias, was associated with thrombotic events. We studied 1014 outpatients sequentially referred for evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3bd050ec81e16baa805b14d358baa6
https://doi.org/10.1097/mbc.0000000000000276
https://doi.org/10.1097/mbc.0000000000000276
Autor:
Karyn F. Siemasko, D.-Q. Li, Christopher S. Schaumburg, Eugene A. Volpe, Niral B. Gandhi, Stephen C. Pflugfelder, Terry G. Coursey, C. S. De Paiva, Jerry Y. Niederkorn, Xiaobo Zhang, Michael E. Stern
Publikováno v:
Mucosal immunology
This study investigated the regulatory function of CD8⁺ cells in T helper-17 (Th17) cell-mediated corneal epithelial barrier disruption that develops in a murine desiccating stress (DS) model that resembles Sjögren syndrome. CD8⁺ cell depletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39454a0f3316155c801d1f637d619ee1
https://doi.org/10.1038/mi.2013.61
https://doi.org/10.1038/mi.2013.61
Autor:
Eugene A. Volpe, William J. Farley, Stephen C. Pflugfelder, Cintia S. de Paiva, Wei Chen, Michael E. Stern, De-Quan Li, Niral B. Gandhi, Jerry Y. Niederkorn, Xiaobo Zhang
Publikováno v:
The American Journal of Pathology. 179:1807-1814
We investigated the role of CD4(+) T-cell-produced interferon (IFN)-γ on corneal epithelial apoptosis in a murine desiccating stress (DS) model that resembles Sjögren's syndrome. The DS model was generated in C57BL/6 (B6) and B6 IFN-γ-knockout (B6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67dd134863ede49c364466db7ad4a190
https://doi.org/10.1016/j.ajpath.2011.06.030
https://doi.org/10.1016/j.ajpath.2011.06.030
Publikováno v:
Journal of American Association for Pediatric Ophthalmology and Strabismus. 22:174-178.e1
Purpose To evaluate the success rate of adjustable suture techniques in horizontal eye muscle surgery in children ≤15 years of age over a 19-year period by a single surgeon. Methods The medical records of all consecutive patients in this age group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97947fb799d9963ffac9dad45bedb6fc
https://doi.org/10.1016/j.jaapos.2018.01.013
https://doi.org/10.1016/j.jaapos.2018.01.013
Autor:
Eugene A. Volpe, Stephen C. Pflugfelder, Terry G. Coursey, Niral B. Gandhi, Cintia S. de Paiva
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 11, p e78508 (2013)
PLoS ONE, Vol 8, Iss 11, p e78508 (2013)
CD4(+) T cells are essential to pathogenesis of ocular surface disease in dry eye. Two subtypes of CD4(+) T cells, Th1 and Th17 cells, function concurrently in dry eye to mediate disease. This occurs in spite of the cross-regulation of IFN-γ and IL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d959b51424e6b64527775f20f7b5ae4b
http://europepmc.org/articles/PMC3817213
http://europepmc.org/articles/PMC3817213
Autor:
Xiaobo Zhang, Niral B. Gandhi, Zhitao Su, Eugene A. Volpe, Flavia S. A. Pelegrino, Cintia S. de Paiva, Salman A. Rahman, De-Quan Li, Stephen C. Pflugfelder
Publikováno v:
Journal of leukocyte biology. 94(6)
TSP-1 is a physiologic activator of TGF-β, a critical induction factor for Th17-mediated immunity. The purpose of this study was to investigate the role of TSP-1 in the induction of the Th17 ocular surface response to DS. TSP-1KO and WT mice were su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09d94036e4ec973f2fde853c949b9b8
https://pubmed.ncbi.nlm.nih.gov/23983225
https://pubmed.ncbi.nlm.nih.gov/23983225
Autor:
C. S. De Paiva, Stephen C. Pflugfelder, Niral B. Gandhi, Xiaobo Zhang, Fan Lu, Jing Lin, D.-Q. Li, Z. Su, Lili Zhang
This study identified a novel phenomenon that dendritic cells (DCs) produced interleukin (IL)-33 via Toll-like receptor (TLR)-mediated innate pathway. Mouse bone marrow–derived DCs were treated with or without microbial pathogens or recombinant mur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dcc63f17f1d76abed85c123c6f4b400
https://europepmc.org/articles/PMC3904307/
https://europepmc.org/articles/PMC3904307/
