Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Niraj Khemka"'
Autor:
Niraj Khemka, Gareth Morris, Laleh Kazemzadeh, Lara S. Costard, Valentin Neubert, Sebastian Bauer, Felix Rosenow, Morten T. Venø, Jørgen Kjems, David C. Henshall, Jochen H. M. Prehn, Niamh M. C. Connolly
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Epileptogenesis is the process by which a normal brain becomes hyperexcitable and capable of generating spontaneous recurrent seizures. The extensive dysregulation of gene expression associated with epileptogenesis is shaped, in part, by mic
Externí odkaz:
https://doaj.org/article/aec36402be9d4848857dd99eb744d751
Publikováno v:
Plant Direct, Vol 5, Iss 3, Pp n/a-n/a (2021)
Abstract MicroRNAs (miRNAs) are non‐coding small RNAs that regulate gene expression at transcriptional and post‐transcriptional levels. The role of miRNAs in seed development and seed size/weight determination is poorly understood in legumes. In
Externí odkaz:
https://doaj.org/article/970a016cdac242d7911ab3f3b2cd247f
Autor:
Annette T. Byrne, Jochen H.M. Prehn, Livio Trusolino, Claudio Isella, Andrea Bertotti, Diether Lambrechts, Enzo Medico, Rodrigo Dienstmann, Josep Tabernero, Guillem Argilés, Patrick Dicker, Matthias P.A. Ebert, Johannes Betge, Luise Halang, Bram Boeckx, Elodie Modave, Evy Vanderheyden, Manuela Salvucci, Eugenia R. Zanella, Francesco Sassi, Andreas U. Lindner, Niraj Khemka, Giorgia Migliardi, Alice C. O'Farrell, Adam Lafferty
Purpose:Regorafenib (REG) is approved for the treatment of metastatic colorectal cancer, but has modest survival benefit and associated toxicities. Robust predictive/early response biomarkers to aid patient stratification are outstanding. We have exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03cb7f23937564cd04f0a66b41f08cc
https://doi.org/10.1158/1078-0432.c.6530519
https://doi.org/10.1158/1078-0432.c.6530519
Autor:
Annette T. Byrne, Jochen H.M. Prehn, Livio Trusolino, Claudio Isella, Andrea Bertotti, Diether Lambrechts, Enzo Medico, Rodrigo Dienstmann, Josep Tabernero, Guillem Argilés, Patrick Dicker, Matthias P.A. Ebert, Johannes Betge, Luise Halang, Bram Boeckx, Elodie Modave, Evy Vanderheyden, Manuela Salvucci, Eugenia R. Zanella, Francesco Sassi, Andreas U. Lindner, Niraj Khemka, Giorgia Migliardi, Alice C. O'Farrell, Adam Lafferty
Supplementary Figures S1 - S8 and Table S1. Fig S1: Analysis of copy number burden in a PDX population trial of REG treated mCRC PDXs. Fig S2: Effect of REG on microvessel density and proliferation according to CNA cluster. Fig S3 - S6: BCL-2 family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f28b84a3384bf08ad570848bf99f729
https://doi.org/10.1158/1078-0432.22480721
https://doi.org/10.1158/1078-0432.22480721
Autor:
Niraj Khemka, Gareth Morris, Laleh Kazemzadeh, Lara S. Costard, Valentin Neubert, Sebastian Bauer, Felix Rosenow, Morten T. Venø, Jørgen Kjems, David C. Henshall, Jochen H. M. Prehn, Niamh M.C. Connolly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62a15e3c174919790de3182739173ec1
https://doi.org/10.2139/ssrn.4397198
https://doi.org/10.2139/ssrn.4397198
Publikováno v:
Planta. 256
The integrated transcriptome data analyses suggested the plausible roles of lncRNAs during seed development in chickpea. The candidate lncRNAs associated with QTLs and those involved in miRNA-mediated seed size/weight determination in chickpea have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad61c39f617af767d05c6a4ec350b65c
https://doi.org/10.1007/s00425-022-03986-0
https://doi.org/10.1007/s00425-022-03986-0
Autor:
Matthias P. Ebert, Patrick Dicker, Livio Trusolino, Jochen H. M. Prehn, Adam Lafferty, Elodie Modave, Alice C. O’Farrell, Enzo Medico, Giorgia Migliardi, Niraj Khemka, Rodrigo Dienstmann, Evy Vanderheyden, Andrea Bertotti, Francesco Sassi, Claudio Isella, Eugenia R. Zanella, Diether Lambrechts, Guillem Argiles, Josep Tabernero, Manuela Salvucci, Annette T. Byrne, Johannes Betge, Luise Halang, Bram Boeckx, Andreas U. Lindner
Publikováno v:
Clin Cancer Res
Purpose: Regorafenib (REG) is approved for the treatment of metastatic colorectal cancer, but has modest survival benefit and associated toxicities. Robust predictive/early response biomarkers to aid patient stratification are outstanding. We have ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bd59b844860eb48b47b1d2324f5576
https://zenodo.org/record/7798369
https://zenodo.org/record/7798369
Publikováno v:
Plant Direct, Vol 5, Iss 3, Pp n/a-n/a (2021)
Plant Direct
Plant Direct
MicroRNAs (miRNAs) are non‐coding small RNAs that regulate gene expression at transcriptional and post‐transcriptional levels. The role of miRNAs in seed development and seed size/weight determination is poorly understood in legumes. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75d16823de46e56b9129c58511bfced
https://doi.org/10.1002/pld3.299
https://doi.org/10.1002/pld3.299
Autor:
Mukesh K. Jain, Rajesh Ghangal, Vikash K. Singh, Niraj Khemka, Rohini Garg, Mohan Singh Rajkumar
Publikováno v:
Legume Genomics ISBN: 9781071602348
In recent years, rapid advancement has been done in generation of genomic resources for the important legume crop chickpea. Here, we provide an update on important advancements made on availability of genomic resources for this crop. The availability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c29965aa8356758e92399d2a6507c52
https://doi.org/10.1007/978-1-0716-0235-5_2
https://doi.org/10.1007/978-1-0716-0235-5_2
Publikováno v:
Legume Genomics ISBN: 9781071602348
Long noncoding RNAs (lncRNAs) are noncoding RNAs with transcript length more than 200 nucleotides. Although poorly conserved, lncRNAs are expressed across diverse species, including plants and animals, and are known to be involved in regulation of va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::036b470d4349d012892f9da585086b24
https://doi.org/10.1007/978-1-0716-0235-5_12
https://doi.org/10.1007/978-1-0716-0235-5_12