Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Niraj, Lodhi"'
Publikováno v:
eLife, Vol 13 (2024)
PARP-1 is central to transcriptional regulation under both normal and stress conditions, with the governing mechanisms yet to be fully understood. Our biochemical and ChIP-seq-based analyses showed that PARP-1 binds specifically to active histone mar
Externí odkaz:
https://doaj.org/article/b031d49111274b33af88331d3a7a6358
Autor:
Niraj Lodhi, Poonam Nagpal, Sreeja Sarojini, Michaela Keck, Yuk Ming Chiu, Zeenath Parvez, Laura Adrianzen, K. Stephen Suh
Publikováno v:
Cancer Reports, Vol 6, Iss 2, Pp n/a-n/a (2023)
Abstract Background Melanoma is one of the most aggressive cancers, with 1.6% of total cancer deaths in the United States. In recent years treatment options for metastatic melanoma have been improved by the FDA approval of new therapeutic agents. How
Externí odkaz:
https://doaj.org/article/0dd368b496634a8fb074961deb9a8779
Publikováno v:
Epigenomes, Vol 7, Iss 2, p 10 (2023)
Epigenetic modifications are heritable, reversible changes in histones or the DNA that control gene functions, being exogenous to the genomic sequence itself. Human diseases, particularly cancer, are frequently connected to epigenetic dysregulations.
Externí odkaz:
https://doaj.org/article/58bbed0101cc425eaf800329bbfb3239
Autor:
Rakesh Srivastava, Niraj Lodhi
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 417 (2022)
Mammalian genomic DNA methylation represents a key epigenetic modification and its dynamic regulation that fine-tunes the gene expression of multiple pathways during development. It maintains the gene expression of one generation of cells; particular
Externí odkaz:
https://doaj.org/article/f817d814ab484875be0332e5c09b206f
Publikováno v:
Molecular Biology Reports. 50:417-431
Tobacco's PR-1a gene is induced by pathogen attack or exogenous application of salicylic acid (SA). Nucleosome mapping and chromatin immunoprecipitation assay were used to delineate the histone modifications on the PR-1a promoter. However, the epigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d35df6b73de23c2a9a2a527d9a3eb4
https://doi.org/10.1007/s11033-022-08074-w
https://doi.org/10.1007/s11033-022-08074-w
Autor:
Colin Thomas, Yingbiao Ji, Niraj Lodhi, Elena Kotova, Aaron Dan Pinnola, Konstantin Golovine, Peter Makhov, Kate Pechenkina, Vladimir Kolenko, Alexei V. Tulin
Publikováno v:
EBioMedicine, Vol 13, Iss C, Pp 90-98 (2016)
The clinical potential of PARP-1 inhibitors has been recognized >10 years ago, prompting intensive research on their pharmacological application in several branches of medicine, particularly in oncology. However, natural or acquired resistance of tum
Externí odkaz:
https://doaj.org/article/2dd741d05de3488380976c9c46ec0094
Autor:
Niraj Lodhi, Poonam Nagpal, Sreeja Sarojini, Michaela Keck, Yuk Ming Chiu, Zeenath Parvez, Laura Adrianzen, K. Stephen Suh
Publikováno v:
Cancer Reports. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a905e6474dfb6cc93d7b42b71d0db8c
https://doi.org/10.1002/cnr2.1733
https://doi.org/10.1002/cnr2.1733
Autor:
Niraj, Lodhi, Poonam, Nagpal, Sreeja, Sarojini, Michaela, Keck, Yuk Ming, Chiu, Zeenath, Parvez, Laura, Adrianzen, K Stephen, Suh
Publikováno v:
Cancer reports (Hoboken, N.J.)REFERENCES.
Melanoma is one of the most aggressive cancers, with 1.6% of total cancer deaths in the United States. In recent years treatment options for metastatic melanoma have been improved by the FDA approval of new therapeutic agents. However, these inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0061267444750d9600114133791c50ce
https://pubmed.ncbi.nlm.nih.gov/36241419
https://pubmed.ncbi.nlm.nih.gov/36241419
Autor:
Noor Siyam, Moe Tun, Nehad M. Ayoub, Lucia Oton-Gonzalez, Kwangsun Stephen Suh, Niraj Lodhi, Angela Gerona, Arati A. Inamdar, Rana Sandhu, Dainelle Morris, Poonam Nagpal
Publikováno v:
Oncotarget
Despite the great efforts for better treatment options for diffuse large B-cell lymphoma (DLBCL) (most common form of non-Hodgkin lymphoma, NHL) to treat and prevent relapse, it continues to be a challenge. Here, we present an overview of DLBCL and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af2b7c502070b308c09ea8f6144326f
http://europepmc.org/articles/PMC7646825
http://europepmc.org/articles/PMC7646825
Publikováno v:
Genes, Vol 12, Iss 1982, p 1982 (2021)
Genes; Volume 12; Issue 12; Pages: 1982
Genes; Volume 12; Issue 12; Pages: 1982
An individual’s gene expression profile changes throughout their life. This change in gene expression is shaped by differences in physiological needs and functions between the younger and older organism. Despite intensive studies, the aging process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051c8a32278e03b0ebb7f31d28199920
https://www.mdpi.com/2073-4425/12/12/1982
https://www.mdpi.com/2073-4425/12/12/1982