Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nira Leider"'
Autor:
Nira Leider, Doron Melamed
Publikováno v:
The Journal of Immunology. 171:2446-2452
Responsiveness of c-Myc oncogene to B cell receptor ligation has been implicated in the induction of apoptosis in transformed and normal immature B cells. These studies provided compelling evidence to link the c-Myc oncogene with the process of negat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c535f8be6a5c974dd480d3b88f1a83d5
https://doi.org/10.4049/jimmunol.171.5.2446
https://doi.org/10.4049/jimmunol.171.5.2446
Publikováno v:
International Immunology. 15:1045-1052
The expression of muH chain is an important checkpoint in B cell development. In mice deficient for IgM transmembrane tail exons (muMT mice) B cell development is blocked at the pro-B stage. However, we showed that Fas-deficient muMT mice (muMT/lpr)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad35dcbdb67f48e4fcab1403016f5d3
https://doi.org/10.1093/intimm/dxg107
https://doi.org/10.1093/intimm/dxg107
Publikováno v:
The Journal of Immunology. 168:5596-5604
Positive signaling is now thought to be important for B cell maturation, although the nature of such signals has not yet been defined. We are studying the regulatory role of B cell Ag receptor (BCR) signaling in mediating positive selection of immatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91bc9820e0bde9425eab311a09cfc333
https://doi.org/10.4049/jimmunol.168.11.5596
https://doi.org/10.4049/jimmunol.168.11.5596
Autor:
Ofra Benny, Efrat Edry, Zohar Keren, Jane Seagal, Marcelle Machluf, Nira Leider, Doron Melamed
Publikováno v:
The Journal of Experimental Medicine
In B lymphocytes, immunoglobulin (Ig)M receptors drive development and construction of naive repertoire, whereas IgG receptors promote formation of the memory B cell compartment. This isotype switching process requires appropriate B cell activation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d83e3f6fab3fdfe73e926c8acd9939e
https://pubmed.ncbi.nlm.nih.gov/14623914
https://pubmed.ncbi.nlm.nih.gov/14623914
Publikováno v:
European journal of immunology. 32(8)
B cell receptor signaling threshold regulates negative selection of autoreactive B cells and determines the mechanism of B cell tolerance. Using mice carrying immunoglobulin transgene specific for MHC class I antigen K(k) (3-83 Tg mice), and IL-7-dri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1acfaa3a9cc38c399568e5c0755c3a81
https://pubmed.ncbi.nlm.nih.gov/12209639
https://pubmed.ncbi.nlm.nih.gov/12209639
Publikováno v:
European Journal of Immunology. 32:2264
B cell receptor signaling threshold regulates negative selection of autoreactive B cells and determines the mechanism of B cell tolerance. Using mice carrying immunoglobulin transgene specific for MHC class I antigen K k (3-83Tg mice), and IL-7-drive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32ffce9552778fb083067e8582f6beba
https://doi.org/10.1002/1521-4141(200208)32:8<2264::aid-immu2264>3.0.co
https://doi.org/10.1002/1521-4141(200208)32:8<2264::aid-immu2264>3.0.co