Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Nir S, Gov"'
Autor:
Raj Kumar Sadhu, Christian Hernandez-Padilla, Yael Eshed Eisenbach, Samo Penič, Lixia Zhang, Harshad D. Vishwasrao, Bahareh Behkam, Konstantinos Konstantopoulos, Hari Shroff, Aleš Iglič, Elior Peles, Amrinder S. Nain, Nir S. Gov
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Protrusions at the leading-edge of a cell play an important role in sensing the extracellular cues during cellular spreading and motility. Recent studies provided indications that these protrusions wrap (coil) around the extracellular fibers
Externí odkaz:
https://doaj.org/article/c56bd7d4832343bf8d4dfb5fdae7a92e
Autor:
Adel Al Jord, Gaëlle Letort, Soline Chanet, Feng-Ching Tsai, Christophe Antoniewski, Adrien Eichmuller, Christelle Da Silva, Jean-René Huynh, Nir S. Gov, Raphaël Voituriez, Marie-Émilie Terret, Marie-Hélène Verlhac
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Cytoskeletal activity generates mechanical forces known to agitate and displace membrane-bound organelles in the cytoplasm. In oocytes, Al Jord et al. discover that these cytoplasmic forces functionally remodel nuclear RNA-processing condensates acro
Externí odkaz:
https://doaj.org/article/edf7a3701dba4bb2be0ace4d6b35c57c
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Eukaryotic cells intrinsically change their shape, by changing the composition of their membrane and by restructuring their underlying cytoskeleton. We present here further studies and extensions of a minimal physical model, describing a closed vesic
Externí odkaz:
https://doaj.org/article/e0c50f65110443be839f812ab6d33bc2
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Cell spreading and motility on an adhesive substrate are driven by the active physical forces generated by the actin cytoskeleton. We have recently shown that coupling curved membrane complexes to protrusive forces, exerted by the actin polymerizatio
Externí odkaz:
https://doaj.org/article/b7405da058c245c885d29526130f9060
Autor:
Raj Kumar Sadhu, Christian Hernandez-Padilla, Yael Eshed Eisenbach, Samo Penič, Lixia Zhang, Harshad D. Vishwasrao, Bahareh Behkam, Konstantinos Konstantopoulos, Hari Shroff, Aleš Iglič, Elior Peles, Amrinder S. Nain, Nir S. Gov
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/e3deb1c61d744c84b0e47d75143efa6e
Autor:
Elya Dekel, Dana Yaffe, Irit Rosenhek-Goldian, Gili Ben-Nissan, Yifat Ofir-Birin, Mattia I. Morandi, Tamar Ziv, Xavier Sisquella, Matthew A. Pimentel, Thomas Nebl, Eugene Kapp, Yael Ohana Daniel, Paula Abou Karam, Daniel Alfandari, Ron Rotkopf, Shimrit Malihi, Tal Block Temin, Debakshi Mullick, Or-Yam Revach, Ariel Rudik, Nir S. Gov, Ido Azuri, Ziv Porat, Giulia Bergamaschi, Raya Sorkin, Gijs J. L. Wuite, Ori Avinoam, Teresa G. Carvalho, Sidney R. Cohen, Michal Sharon, Neta Regev-Rudzki
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Plasmodium falciparum secretes extracellular vesicles (EVs) while growing inside red blood cells (RBCs). Here the authors show that these EVs contain assembled and functional 20S proteasome complexes that remodel the cytoskeleton of naïve human RBCs
Externí odkaz:
https://doaj.org/article/2714bdc7c6d440079ba403f2120173c1
Publikováno v:
Frontiers in Applied Mathematics and Statistics, Vol 7 (2021)
Cooperative transport of large food loads by Paratrechina longicornis ants demands repeated decision-making. Inspired by the Evidence Accumulation (EA) model classically used to describe decision-making in the brain, we conducted a binary choice expe
Externí odkaz:
https://doaj.org/article/cdfae155defa48539a8d6da998988def
Autor:
Raj Kumar Sadhu, Sarah R. Barger, Samo Penič, Aleš Iglič, Mira Krendel, Nils C. Gauthier, Nir S. Gov
Publikováno v:
Soft Matter. 19:31-43
Phagocytosis is the process of engulfment and internalization of comparatively large particles by cells, and plays a central role in the functioning of our immune system. We study the process of phagocytosis by considering a simplified coarse grained
Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Circular dorsal ruffles (CDRs) are important for the vesicular uptake of extracellular matter, but the basis of their wave dynamics is not understood. Here, the authors propose and experimentally test a bistable reaction-diffusion system, which they
Externí odkaz:
https://doaj.org/article/b0a7abdcb6774d989d06bfab761b2ebc
Autor:
Brian R Graziano, Jason P Town, Ewa Sitarska, Tamas L Nagy, Miha Fošnarič, Samo Penič, Aleš Iglič, Veronika Kralj-Iglič, Nir S Gov, Alba Diz-Muñoz, Orion D Weiner
Publikováno v:
PLoS Biology, Vol 17, Iss 10, p e3000457 (2019)
Migratory cells use distinct motility modes to navigate different microenvironments, but it is unclear whether these modes rely on the same core set of polarity components. To investigate this, we disrupted actin-related protein 2/3 (Arp2/3) and the
Externí odkaz:
https://doaj.org/article/3f153d5d621647d69fdf25c9aa2954fd