Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nir Gov"'
Publikováno v:
eLife, Vol 12 (2023)
Actin dynamics in cell motility, division, and phagocytosis is regulated by complex factors with multiple feedback loops, often leading to emergent dynamic patterns in the form of propagating waves of actin polymerization activity that are poorly und
Externí odkaz:
https://doaj.org/article/6f625e559415415381c8890028072409
Autor:
Catherine Leonard, Hélène Pollet, Christiane Vermylen, Nir Gov, Donatienne Tyteca, Marie-Paule Mingeot-Leclercq
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 6, Pp 2563-2582 (2018)
Background/Aims: Transient nanometric cholesterol- and sphingolipid-enriched domains, called rafts, are characterized by higher lipid order as compared to surrounding lipids. Here, we asked whether the seminal concept of highly ordered rafts could be
Externí odkaz:
https://doaj.org/article/0dd5404ec5224e5ab6e2c0751e698349
Publikováno v:
Physical Review Research, Vol 2, Iss 1, p 013003 (2020)
The dynamics of active particles is of interest at many levels and is the focus of theoretical and experimental research. There have been many attempts to describe the dynamics of particles affected by random active forces in terms of an effective te
Externí odkaz:
https://doaj.org/article/5f11dd923b204086927a1759deb8ae8c
Dynamics of actin waves on patterned substrates: a quantitative analysis of circular dorsal ruffles.
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0115857 (2015)
Circular Dorsal Ruffles (CDRs) have been known for decades, but the mechanism that organizes these actin waves remains unclear. In this article we systematically analyze the dynamics of CDRs on fibroblasts with respect to characteristics of current m
Externí odkaz:
https://doaj.org/article/2704d0713375434f902ddb21fd94839d
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18635 (2011)
Cells exhibit propagating membrane waves which involve the actin cytoskeleton. One type of such membranal waves are Circular Dorsal Ruffles (CDR) which are related to endocytosis and receptor internalization. Experimentally, CDRs have been associated
Externí odkaz:
https://doaj.org/article/c96f329d5a3c49b9a1617951c5f631c5
Cell spreading and motility on an adhesive substrate are driven by the active physical forces generated by the actin cytoskeleton. We have recently shown that coupling curved membrane complexes to protrusive forces, exerted by the actin polymerizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732c26bcf20d7eb0ce9d4196d11c4bcf
https://doi.org/10.1101/2023.03.27.534326
https://doi.org/10.1101/2023.03.27.534326
Eukaryotic cells intrinsically change their shape, by changing the composition of their membrane and by restructuring their underlying cytoskeleton. We present here further studies and extensions of a minimal physical model, describing a closed vesic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c75272ab548d52433bbdd92bdf69b8b
https://doi.org/10.1101/2023.01.31.526240
https://doi.org/10.1101/2023.01.31.526240
Autor:
Jonathan E. Ron, Michele Cresanti, Johan-Moritz Kux, Jiayi Liu, Nabil Al-Dam, Pascale Monzo, Nils C. Gauthier, Pablo J. Saez, Nir Gov
Motile cells inside living tissues often encounter junctions, where their path branches into several alternative directions of migration. We present a theoretical model of cellular polarization for cells migrating along one-dimensional lines, arrivin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de54021d40dd01bc576462699567a4b3
https://doi.org/10.1101/2022.10.14.512239
https://doi.org/10.1101/2022.10.14.512239
Autor:
Wei, Dai, Xiaoran, Guo, Yuansheng, Cao, James A, Mondo, Joseph P, Campanale, Brandon J, Montell, Haley, Burrous, Sebastian, Streichan, Nir, Gov, Wouter-Jan, Rappel, Denise J, Montell
Publikováno v:
Science
Moving cells can sense and respond to physical features of the microenvironment, however in vivo the significance of tissue topography is mostly unknown. Here we use the Drosophila border cells, an established model for in vivo cell migration, to stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::adc6f6156f5559bf0d975f09639f04aa
https://pubmed.ncbi.nlm.nih.gov/33214282
https://pubmed.ncbi.nlm.nih.gov/33214282
Publikováno v:
Biophysical Journal. 90:454-469
A motile cell, when stimulated, shows a dramatic increase in the activity of its membrane, manifested by the appearance of dynamic membrane structures such as lamellipodia, filopodia and membrane ruffles. The external stimulus turns on membrane bound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f02aaffd93ba078c6b4b63c9f473602
https://doi.org/10.1529/biophysj.105.062224
https://doi.org/10.1529/biophysj.105.062224