Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Nir Ben‐Tal"'
Autor:
Ayca Ersoy, Bengi Altintel, Nurit Livnat Levanon, Nir Ben-Tal, Turkan Haliloglu, Oded Lewinson
Publikováno v:
eLife, Vol 12 (2023)
Malfunction of the CFTR protein results in cystic fibrosis, one of the most common hereditary diseases. CFTR functions as an anion channel, the gating of which is controlled by long-range allosteric communications. Allostery also has direct bearings
Externí odkaz:
https://doaj.org/article/28139476f459474b852567b971d3381c
Autor:
Ido Caspy, Tom Schwartz, Vinzenz Bayro-Kaiser, Mariia Fadeeva, Amit Kessel, Nir Ben-Tal, Nathan Nelson
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Caspy et al. report the structure of PSI from a temperature-sensitive photoautotrophic PSII mutant of Chlamydomonas reinhardtii (TSP4), and report the distribution of conserved water molecules in the structure from cyanobacterial to higher plant PSI.
Externí odkaz:
https://doaj.org/article/5058ae08e01f4f2aa044a9def315319b
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/2d2738565626488083509b2aadba85bb
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S14, Pp 1-10 (2019)
Abstract Background Predicting the effect of single point variations on protein stability constitutes a crucial step toward understanding the relationship between protein structure and function. To this end, several methods have been developed to pre
Externí odkaz:
https://doaj.org/article/034989d72abe4bc9a9797911b04d7791
Autor:
Liam M Longo, Jagoda Jabłońska, Pratik Vyas, Manil Kanade, Rachel Kolodny, Nir Ben-Tal, Dan S Tawfik
Publikováno v:
eLife, Vol 9 (2020)
This article is dedicated to the memory of Michael G. Rossmann. Dating back to the last universal common ancestor, P-loop NTPases and Rossmanns comprise the most ubiquitous and diverse enzyme lineages. Despite similarities in their overall architectu
Externí odkaz:
https://doaj.org/article/78e631a8267442aaa3cc5e6804dd8ea3
Autor:
Gal Masrati, Manish Dwivedi, Abraham Rimon, Yael Gluck-Margolin, Amit Kessel, Haim Ashkenazy, Itay Mayrose, Etana Padan, Nir Ben-Tal
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Cation/proton antiporters (CPAs) play a major role in maintaining living cells’ homeostasis and are divided in two main groups: CPA1 and CPA2. Here authors use a comprehensive evolutionary analysis of 6537 representative CPAs and reveal a sequence
Externí odkaz:
https://doaj.org/article/f15fa41a1567456bbadf5b59246f8cd7
Autor:
Meghan Whitney Franklin, Sergey Nepomnyachyi, Ryan Feehan, Nir Ben-Tal, Rachel Kolodny, Joanna SG Slusky
Publikováno v:
eLife, Vol 7 (2018)
Outer membrane proteins (OMPs) are the proteins in the surface of Gram-negative bacteria. These proteins have diverse functions but a single topology: the β-barrel. Sequence analysis has suggested that this common fold is a β-hairpin repeat protein
Externí odkaz:
https://doaj.org/article/69259f8ebb4d4194a9db6262707ed056
Autor:
Matthew A Oberhardt, Raphy Zarecki, Leah Reshef, Fangfang Xia, Miquel Duran-Frigola, Rachel Schreiber, Christopher S Henry, Nir Ben-Tal, Daniel J Dwyer, Uri Gophna, Eytan Ruppin
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 1, p e1004705 (2016)
Recent insights suggest that non-specific and/or promiscuous enzymes are common and active across life. Understanding the role of such enzymes is an important open question in biology. Here we develop a genome-wide method, PROPER, that uses a permiss
Externí odkaz:
https://doaj.org/article/4ec339628dd24f6596250a5429b8f4bb
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 10, p e1004461 (2015)
Protein-protein interfaces have been evolutionarily-designed to enable transduction between the interacting proteins. Thus, we hypothesize that analysis of the dynamics of the complex can reveal details about the nature of the interaction, and in par
Externí odkaz:
https://doaj.org/article/3ff12170bc824125bfce94fcbdcfa0d3
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 12, p e1003976 (2014)
Cyclic nucleotide-gated (CNG) ion channels are nonselective cation channels, essential for visual and olfactory sensory transduction. Although the channels include voltage-sensor domains (VSDs), their conductance is thought to be independent of the m
Externí odkaz:
https://doaj.org/article/f2ae6a99fa0349efb26faf96d2b07a1a