Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Nir, Osherov"'
Autor:
Mariana Handelman, Zohar Meir, Yona Shadkchan, Ammar Abo Kandil, Orin Amano, Melani Mariscal, Manuel Sánchez López-Berges, Nir Osherov
Publikováno v:
mSphere, Vol 9, Iss 6 (2024)
ABSTRACT Aspergillus fumigatus is the leading cause of severe mold infections in immunocompromised patients. This common fungus possesses innate attributes that allow it to evade the immune system, including its ability to survive the high copper (Cu
Externí odkaz:
https://doaj.org/article/37379d58dd98438eacd132bdb868ce27
Autor:
Qiqi Wang, Yun Li, Yanming Li, Nir Osherov, Gustavo H. Goldman, Paul E. Verweij, Bo Zheng, Ruoyu Li, Wei Chen, Tianyu Liang, Zhe Wan, Wei Liu
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 1435-1438 (2022)
Aspergillus luchuensis, an industrially important member of Aspergillus species belonging to section Nigri used in fermentation in East Asia, was isolated from an immunocompromised patient with probable invasive pulmonary aspergillosis who failed vor
Externí odkaz:
https://doaj.org/article/1b9a1cd9afc14b0f92cd7eb4bc203293
Autor:
Yoav Charpak-Amikam, Tom Lapidus, Batya Isaacson, Alexandra Duev-Cohen, Tal Levinson, Adi Elbaz, Francesca Levi-Schaffer, Nir Osherov, Gilad Bachrach, Lois L. Hoyer, Maya Korem, Ronen Ben-Ami, Ofer Mandelboim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Natural killer cells have emerged as critical immune cells in the response to fungal infection. Here the authors identify how Candida albicans evades the natural killer cell response via expression of ligands that directly modify the natural killer c
Externí odkaz:
https://doaj.org/article/5d4f202e0f1b45458f7c54448f86e0ce
Autor:
Duaa Anabosi, Zohar Meir, Yana Shadkchan, Mariana Handelman, Ammar Abou-Kandil, Annie Yap, Daniel Urlings, Morgan S. Gold, Sven Krappmann, Hubertus Haas, Nir Osherov
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 2186-2200 (2021)
Aspergillus fumigatus is the leading cause of life-threatening invasive mold infections in immunocompromised individuals. This ubiquitous saprophyte possesses several natural attributes allowing it to evade the immune system, including the ability to
Externí odkaz:
https://doaj.org/article/b36694be212d4034bf7dbe25b2a07ff7
Autor:
Mario Aguiar, Thomas Orasch, Yana Shadkchan, Patricia Caballero, Joachim Pfister, Luis Enrique Sastré-Velásquez, Fabio Gsaller, Clemens Decristoforo, Nir Osherov, Hubertus Haas
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Siderophores play an important role in fungal virulence, serving as trackers for in vivo imaging and as biomarkers of fungal infections. However, siderophore uptake is only partially characterized. As the major cause of aspergillosis, Asperg
Externí odkaz:
https://doaj.org/article/fc6bc1dd47b144078ad2051d647d196d
Autor:
Mariana Handelman, Nir Osherov
Publikováno v:
Frontiers in Fungal Biology, Vol 3 (2022)
The leading fungal pathogens causing systemic infections in humans are Candida spp., Aspergillus fumigatus, and Cryptococcus neoformans. The major class of antifungals used to treat such infections are the triazoles, which target the cytochrome P450
Externí odkaz:
https://doaj.org/article/fe75db273e5e45f1855f707f2bc8714d
Autor:
Mariana Handelman, Nir Osherov
Publikováno v:
Journal of Fungi, Vol 9, Iss 6, p 644 (2023)
Aspergillus fumigatus is a common human fungal pathogen that can cause a range of diseases. Triazoles are used to treat A. fumigatus infections, but resistance is increasing due to mutations in genes such as cyp51A, hmg1 and overexpression of efflux
Externí odkaz:
https://doaj.org/article/71b24ae228764c9880398804a95141bc
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Aspergillus fumigatus is the primary mold pathogen in humans. It can cause a wide range of diseases in humans, with high mortality rates in immunocompromised patients. The first-line treatments for invasive A. fumigatus infections are the tr
Externí odkaz:
https://doaj.org/article/1670dc4980c149cf8e6a303acceb39df
Autor:
Hila Werner, Ammar Abou Kandil, Zohar Meir, Yehonathan Malis, Yona Shadkchan, Gal Masrati, Nir Ben-Tal, Koret Hirschberg, Nir Osherov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3705 (2023)
The opportunistic fungus Aspergillus fumigatus is the primary invasive mold pathogen in humans, and is responsible for an estimated 200,000 yearly deaths worldwide. Most fatalities occur in immunocompromised patients who lack the cellular and humoral
Externí odkaz:
https://doaj.org/article/a06a15ad7cfa4de7a91c49d59f3b165f
Autor:
Thomas Orasch, Anna-Maria Dietl, Yana Shadkchan, Ulrike Binder, Ingo Bauer, Cornelia Lass-Flörl, Nir Osherov, Hubertus Haas
Publikováno v:
Virulence, Vol 10, Iss 1, Pp 925-934 (2019)
In contrast to mammalia, fungi are able to synthesize the branched-chain amino acid leucine de novo. Recently, the transcription factor LeuB has been shown to cross-regulate leucine biosynthesis, nitrogen metabolism and iron homeostasis in Aspergillu
Externí odkaz:
https://doaj.org/article/dae059ba5a384f48b7621b5c1330a22d