Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nipunika Somatilaka"'
Autor:
Sun-Hee Hwang, Kevin Andrew White, Bandarigoda Nipunika Somatilaka, Baolin Wang, Saikat Mukhopadhyay
Publikováno v:
PLoS Genetics, Vol 19, Iss 11, p e1011028 (2023)
A fundamental problem in tissue morphogenesis is identifying how subcellular signaling regulates mesoscale organization of tissues. The primary cilium is a paradigmatic organelle for compartmentalized subcellular signaling. How signaling emanating fr
Externí odkaz:
https://doaj.org/article/c97c4b27da334d38b1440624920eace2
Publikováno v:
Cancer Research. 83:4471-4471
Introduction: Neurofibromatosis Type 1 (NF1) results from mutations in the NF1 gene that inactivate the tumor suppressor, neurofibromin. This leads to hyperactive RAS signaling that predisposes NF1 patients to tumor development. Over time, some of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a95db21b65a895277ee19acd6bc499d0
https://doi.org/10.1158/1538-7445.am2023-4471
https://doi.org/10.1158/1538-7445.am2023-4471
Publikováno v:
Cancer Research. 83:5170-5170
Introduction: Neurofibromatosis Type 1 (NF1) is caused by mutations in the NF1 gene that encodes neurofibromin, a RAS GTPase-Activating Protein. Inactivating NF1 mutations result in hyperactivation of RAS-mediated signaling. NF1 patients develop beni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f734602debfa812acd1ba6cc1f1682f
https://doi.org/10.1158/1538-7445.am2023-5170
https://doi.org/10.1158/1538-7445.am2023-5170
Publikováno v:
Oncogene. 41(17)
Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive, invasive cancer that comprise around 10% of all soft tissue sarcomas and develop in about 8-13% of patients with Neurofibromatosis Type 1. They are associated with poor prognosis and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57523c79bf64950c9c79edcb031d5ed
https://pubmed.ncbi.nlm.nih.gov/35393544
https://pubmed.ncbi.nlm.nih.gov/35393544
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2374
The identity of ventral neural progenitors in the neural tube is largely dependent on Hedgehog (Hh) signaling. Variations in staining patterns are excellent indicators of aberrant Hh signaling. Here we describe the basic protocol to stain for progeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7492c0efef636df4842b171e2f1a2f9e
https://pubmed.ncbi.nlm.nih.gov/34562243
https://pubmed.ncbi.nlm.nih.gov/34562243