Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nipuni D. Nagahawatte"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Pacing has been proposed as a therapy to restore function in motility disorders associated with electrical dysrhythmias. The spatial response of bioelectrical activity in the small intestine to pacing is poorly understood due to a lack of hi
Externí odkaz:
https://doaj.org/article/531688a6089248cca421544a77dee5c5
Autor:
Leo K. Cheng, Nipuni D. Nagahawatte, Recep Avci, Peng Du, Zhongming Liu, Niranchan Paskaranandavadivel
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Gastric pacing and stimulation strategies were first proposed in the 1960s to treat motility disorders. However, there has been relatively limited clinical translation of these techniques. Experimental investigations have been critical in advancing o
Externí odkaz:
https://doaj.org/article/0e73093b512144ceb5a3fab53550fcbb
Autor:
Nipuni D. Nagahawatte, Recep Avci, Niranchan Paskaranandavadivel, Timothy R. Angeli-Gordon, Leo K. Cheng
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 324:G329-G340
A novel surface-contact electrode array customized for the small intestine anatomy enabled simultaneous pacing and high-resolution response mapping. The spatial response of small intestine bioelectrical activity to pacing was mapped for the first tim
Autor:
Nipuni D. Nagahawatte, Leo K. Cheng, Recep Avci, Laura R. Bear, Niranchan Paskaranandavadivel
Publikováno v:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2022
Cardiac pacing is a clinical therapy widely used for treating irregular heart rhythms. Equivalent techniques for the treatment of gastric functional motility disorders hold great potential. Accurate analysis of pacing studies is often hindered by the
Autor:
Nipuni D. Nagahawatte, Hanyu Zhang, Niranchan Paskaranandavadivel, Haley N. Patton, Amy S. Garrett, Timothy R. Angeli-Gordon, Linley Nisbet, Jack M. Rogers, Leo K. Cheng
Publikováno v:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2022
Gastric pacing is an attractive therapeutic approach for correcting abnormal bioelectrical activity. While high-resolution (HR) electrical mapping techniques have largely contributed to the current understanding of the effect of pacing on the electro
Autor:
Nipuni D. Nagahawatte, Leo K. Cheng, Recep Avci, Timothy R. Angeli‐Gordon, Niranchan Paskaranandavadivel
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility SocietyREFERENCES. 35(1)
The efficacy of conventional treatments for severe and chronic functional motility disorders remains limited. High-energy pacing is a promising alternative therapy for patients that fail conventional treatment. Pacing primarily regulates gut motility
Autor:
Nipuni D. Nagahawatte, Niranchan Paskaranandavadivel, Laura R. Bear, Recep Avci, Leo K. Cheng
Publikováno v:
Computers in Biology and Medicine. 155:106673
Publikováno v:
2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).
The motility of the gut is central to digestion and is coordinated, in part, by bioelectrical events known as slow waves. While the nature of these events is well defined in-vivo, the temporal response of ex-vivo gastrointestinal myoelectrical activi
Autor:
Niranchan Paskaranandavadivel, Nipuni D Nagahawatte, Recep Avci, Timothy R. Angeli-Gordon, Leo K. Cheng
Publikováno v:
Physiological measurement. 42(3)
Objective. High-resolution serosal recordings provide detailed information about the bioelectrical conduction patterns in the gastrointestinal (GI) tract. However, equivalent knowledge about the electrical activity through the GI tract wall remains l
Autor:
Nipuni D Nagahawatte, Niranchan Paskaranandavadivel, Recep Avci, Leo K. Cheng, Timothy R. Angeli
Publikováno v:
EMBC
Gastrointestinal slow wave activity is, in part, responsible for governing gut motility. Dysrhythmic slow wave activity has been associated with a number of functional motility disorders, but the mechanisms involved are poorly understood. There exist