Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Nipun Malhotra"'
Publikováno v:
Monaldi Archives for Chest Disease (2024)
Though there has been advancement in the management of lung cancer, it is not well utilized due to its limited availability and high cost. This is a prospective observational study done at a tertiary care center from January 2014 to December 2022, in
Externí odkaz:
https://doaj.org/article/3dfa829b5f0f463b845691b73bfa59f5
Autor:
Siddhartha Mishra, Nipun Malhotra, Benoît Laleu, Soumyananda Chakraborti, Manickam Yogavel, Amit Sharma
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110049- (2024)
Summary: The prolyl-tRNA synthetase (PRS) is an essential enzyme for protein translation and a validated target against malaria parasite. We describe five ATP mimetics (L95, L96, L97, L35, and L36) against PRS, exhibiting enhanced thermal stabilities
Externí odkaz:
https://doaj.org/article/af630037dd0645c6b8cbafbe9a69bcdc
Autor:
Nipun Malhotra, Dipti Gothi, Mahismita Patro, Rahul Kumar, Shweta Anand, Anshul Jain, Sunil Kumar Agarwal, Mohit Agarwal, Utkarsh Gupta
Publikováno v:
Journal of Advanced Lung Health, Vol 4, Iss 2, Pp 70-76 (2024)
Introduction: The patient data from the third wave of coronavirus disease 2019 (COVID-19) pandemic in New Delhi caused by the Omicron variant in terms of severity of disease, incidental diagnosis, outcome, and effect of vaccination are relatively lac
Externí odkaz:
https://doaj.org/article/3364619846204d5aaadbfd81f83893ee
Autor:
Mahismita Patro, Dipti Gothi, Shweta Anand, Dweepala P. D. K Priyadarshini, Umesh C Ojha, Ramesh S Pal, Nipun Malhotra, Rahul Kumar, Anshul Jain, Sunil Kumar, Pranzal Agarwal
Publikováno v:
Lung India, Vol 41, Iss 2, Pp 103-109 (2024)
Introduction: We undertook the first study from India to evaluate the long-term health effects of coronavirus disease 2019 (COVID-19). Methods: The patients enrolled in our post-COVID-19 clinic were followed up for assessment at 1, 3, 6 and 12 months
Externí odkaz:
https://doaj.org/article/97daee0760ba49aeacaff1b70d9b10eb
Publikováno v:
Lung India, Vol 41, Iss 2, Pp 81-83 (2024)
Externí odkaz:
https://doaj.org/article/6ed8954c67894630a8cac9fa4b8dd20b
Autor:
GeunYoung Sim, Audrey C. Kehling, Mi Seul Park, Cameron Divoky, Huaqun Zhang, Nipun Malhotra, Jackson Secor, Kotaro Nakanishi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) are loaded into Argonaute (AGO) proteins, forming RNA-induced silencing complexes (RISCs). The assembly process establishes the seed, central, 3′ supplementary, and tail regions across
Externí odkaz:
https://doaj.org/article/1c53bc415af844f9a14a8991e32f3644
Publikováno v:
Monaldi Archives for Chest Disease (2024)
Level I conventional polysomnography (PSG), the gold standard for diagnosing obstructive sleep apnea (OSA), requires an overnight stay. This study evaluated the role of daytime PSG as an alternative diagnostic tool. A prospective cohort study was und
Externí odkaz:
https://doaj.org/article/1e21ceab8acf482181903bcc0f393321
Publikováno v:
The Journal of Association of Chest Physicians, Vol 11, Iss 3, Pp 152-157 (2023)
COVID-19 was first identified as a new disease in December 2019. It’s now more than 2 years since its discovery and much research has been done. Still, there are some aspects in the pathogenesis and management that have not been completely understo
Externí odkaz:
https://doaj.org/article/283e714e3e644d32aad53e5b15806a81
Publikováno v:
Lung India, Vol 40, Iss 4, Pp 321-326 (2023)
Background: Restless leg syndrome (RLS) is common among patients with obstructive sleep apnoea (OSA) but the prognostic importance of this is not studied. We have called OSA and RLS coexistence as ComOSAR. Materials and Methods: A prospective observa
Externí odkaz:
https://doaj.org/article/df7a6880a2fb451ab7e9b57e2dfc3179
Autor:
Manickam Yogavel, Alexandre Bougdour, Siddhartha Mishra, Nipun Malhotra, Jyoti Chhibber-Goel, Valeria Bellini, Karl Harlos, Benoît Laleu, Mohamed-Ali Hakimi, Amit Sharma
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011124 (2023)
The prolyl-tRNA synthetase (PRS) is a validated drug target for febrifugine and its synthetic analog halofuginone (HFG) against multiple apicomplexan parasites including Plasmodium falciparum and Toxoplasma gondii. Here, a novel ATP-mimetic centered
Externí odkaz:
https://doaj.org/article/e8c18ac0c4d34cadb55ade27bc2b2c94