Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ninus Caram-Lelham"'
Autor:
Mario G. Fsadni, Evelien Vandewalle, Lieve Moons, Ingeborg Stalmans, Patrizia Caldirola, Grit Zahn, Tine Van Bergen, Ninus Caram-Lelham
Purpose To evaluate the therapeutic potential of the small molecule integrin α5β1 inhibitor, CLT-28643, to improve the filtering surgery outcome in a mouse model. Different dose regimens and administration routes of the inhibitor were compared with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158fafd267763d418799017914d30231
https://lirias.kuleuven.be/handle/123456789/558002
https://lirias.kuleuven.be/handle/123456789/558002
Autor:
Mario G. Fsadni, Maximilian Schultheiss, Karl U. Bartz-Schmidt, Martin S. Spitzer, Ninus Caram-Lelham, Eva-Maria Konrad, Sven Schnichels, Patrizia Caldirola, Grit Zahn
Publikováno v:
Acta ophthalmologica. 95(1)
Purpose Glaucoma filtration surgery (GFS) fails due to fibrosis. The α5β1-integrin plays a pivotal role in fibrosis, angiogenesis and inflammation. This is the first experiment evaluating the prevention of fibrosis after GFS by a specific small mol
Autor:
Patrizia Caldirola, T Van Bergen, Grit Zahn, Ingeborg Stalmans, Ninus Caram-Lelham, Mario G. Fsadni, Evelien Vandewalle
Publikováno v:
Acta Ophthalmologica. 92
Purpose The aim of this study was to evaluate the therapeutic potential of α5β1-integrin inhibitor (CLT-28643) to improve the outcome of filtering surgery in a mouse model. Different dose regimen and administration routes of the inhibitor were comp
Autor:
Allan S. Hoffman, Lotte Kreilgaard, Ninus Caram-Lelham, Dean K. Pettit, Wayne R. Gombotz, Chad D. Brown, Masashi Nakakura
Publikováno v:
Journal of Controlled Release. 72:35-46
We have prepared a new formulation for mucosal delivery of GM-CSF or PEGylated GM-CSF based on a chitosan carrier plus added glycerol to control the rate of release of the protein. Thin dry films comprised of various weight ratios of chitosan to glyc
Publikováno v:
Langmuir. 16:313-317
The interaction between dextran sulfate (DxS), of different charge density, and three cationic amphiphiles varying with respect to hydrophobicity, was investigated by means of equilibrium dialysis and surface tension. The hydrophobicity of the amphip
Autor:
Lars-Olof Sundelöf, Ninus Caram-Lelham
Publikováno v:
Biopolymers. 39:387-393
For the system kappa-carrageenan/amitriptyline it is shown that the degree of binding of amitriptyline is closely related to the carrageenan conformation as regulated by the counterions (Na+ or K+). The adsorption becomes much more pronounced when th
Publikováno v:
Carbohydrate Polymers. 34:149-156
The formation of polyelectrolyte complexes (PECs) between chitosan varying in degree of deacetylation (DD) and κ-, ι- and λ-carrageenan, respectively, was investigated, in moderately concentrated solutions, with emphasis on the effect of charge de
Publikováno v:
Biopolymers. 41:765-772
The binding of three different amphiphiles (with different hydrophobic characters) to oppositely charged polyelectrolytes (κ-carrageenan, dextran sulphate, alginate, and hyaluronan) is investigated. It is shown that the degree of binding is related
Autor:
Ninus Caram-Lelham, Lars-Olof Sundelöf
Publikováno v:
Pharmaceutical Research. 13:920-925
The effect of hydrophobic character of drugs and helix-coil transition of kappa-carrageenan on the polyelectrolyte-drug interaction
Publikováno v:
Carbohydrate Research. 273:71-76
PREPARATIVE SEPARATION OF OLIGOSACCHARIDES FROM KAPPA-CARRAGEENAN, SODIUM HYALURONATE, AND DEXTRAN BY SUPERDEX(TM) 30 PREP GRADE