Integrative analysis in head and neck cancer reveals distinct role of miRNome and methylome as tumour epigenetic drivers

Autor: Katarina Mandić, Nina Milutin Gašperov, Ksenija Božinović, Emil Dediol, Jure Krasić, Nino Sinčić, Magdalena Grce, Ivan Sabol, Anja Barešić

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Abstract Head and neck cancer is the sixth most common malignancy worldwide, with the relatively low 5-year survival rate, mainly because it is diagnosed at a late stage. Infection with HPV is a well known aetiology, which affects the nature of these

Externí odkaz: https://doaj.org/article/aeba350ff6174d6ca201d19bdaac9dae

Global DNA methylation and chondrogenesis of rat limb buds in a three-dimensional organ culture system

Autor: Vedrana Mužić Radović, Paula Bunoza, Tihana Marić, Marta Himelreich-Perić, Floriana Bulić-Jakuš, Marta Takahashi, Gordana Jurić-Lekić, Nino Sinčić, Davor Ježek, Ana Katušić-Bojanac

Publikováno v: Biomolecules & Biomedicine, Vol 22, Iss 4 (2022)

Although DNA methylation epigenetically regulates development, data on global DNA methylation during development of limb buds (LBs) are scarce. We aimed to investigate the global DNA methylation developmental dynamics in rat LBs cultivated in a serum

Externí odkaz: https://doaj.org/article/ca93b71f8acb4b7f94f5a5f459f8032c

Leydig Cells in Patients with Non-Obstructive Azoospermia: Do They Really Proliferate?

Autor: Dinko Hauptman, Marta Himelreich Perić, Tihana Marić, Ana Katušić Bojanac, Nino Sinčić, Zoran Zimak, Željko Kaštelan, Davor Ježek

Publikováno v: Life, Vol 11, Iss 11, p 1266 (2021)

Background: Non-obstructive azoospermia (NOA) is a form of male infertility caused by disorders of the testicular parenchyma and impaired spermatogenesis. This study aimed to investigate the nature of Leydig cell changes in patients with NOA, especia

Externí odkaz: https://doaj.org/article/9117d9785a5643b9bad986c60bb377ba

Transmembranous and enchondral osteogenesis in transplants of rat limb buds cultivated in serum‐ and protein‐free culture medium

Autor: Marta Himelreich Perić, Vedrana Mužić‐Radović, Tihana Marić, Floriana Bulić‐Jakuš, Gordana Jurić‐Lekić, Marta Takahashi, Nino Sinčić, Davor Ježek, Ana Katušić‐Bojanac

Cartilage differentiates in rat limb buds cultivated in a chemically defined protein-free medium in the same manner as in the richer serum- supplemented medium. We aimed to investigate the remaining differentiation potential of pre- cultivated limb b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7299d8c1706db3d5958a221aa38b9a8
https://doi.org/10.1111/ahe.12835

Extended Prophylactic Effect of N-tert-Butyl-α-phenylnitron against Oxidative/Nitrosative Damage Caused by the DNA-Hypomethylating Drug 5-Azacytidine in the Rat Placenta

Autor: Nikola Sobočan, Marta Himelreich-Perić, Ana Katušić-Bojanac, Jure Krasić, Nino Sinčić, Željka Majić, Gordana Jurić-Lekić, Ljiljana Šerman, Andreja Marić, Davor Ježek, Floriana Bulić-Jakuš

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 603
International Journal of Molecular Sciences, Vol 23, Iss 603, p 603 (2022)
International Journal of Molecular Sciences

Antioxidant N-tert-Butyl-α-phenylnitron (PBN) partly protected embryos from the negative effects of a DNA demethylating drug 5-azacytidine during pregnancy. Our aim was to investigate PBN’s impact on the placenta. Fischer rat dams were treated on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fdb5992b1798da16989b4cf40783133