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Publikováno v:
Problems in oncology. 67:344-349
Immunological synapse (IS) is a high-specialized connection between a T-lymphocyte and an antigen-presenting cell (APC), consisting of a cluster of T-cell receptors (TCR) surrounded by a ring of adhesion molecules. It has now been shown that formatio
Autor:
Natalya Avdonkina, Nino Pipia, Tatyana Nekhaeva, Aleksey Novik, Georgiy Gafton, Natalya Yemelyanova, Anna Danilova, Irina Baldueva
Publikováno v:
Problems in oncology. 64:400-407
In tumor microenvironment the self-maintenance condition of T-regulatory lymphocytes (Treg) are created by tumor cells due to the production of vascular endothelial growth factor VEGF and chemokine CCL2. In the present work there was evaluated the qu
Autor:
Anna Semenova, N. Avdokina, Anna Danilova, Yuriy Komarov, Natalya Yemelyanova, Aleksey Belyaev, Mark Gelfond, Aleksey Novik, Irina Baldueva, Aleksandr Shcherbakov, Tatyana Nekhaeva, Olga Galiullina, Nino Pipia, Yekaterina Anokhina, Dilorom Latipova, Svetlana Protsenko, Tatyana Semiglazova, Gulfiya Midhatovna Teletaeva, Z. S. Kotova
Publikováno v:
Problems in oncology. 63:336-345
There are described the results of clinical and immunological efficacy assessment of active specific immunotherapy with autologous immature dendritic cells (DC) combined with photodynamic therapy (PDT) and cyclophosphamide (C) in disseminated melanom
Autor:
A. V. Misyurin, Anna Danilova, Aleksei Viktorovich Novik, Irina Baldueva, Dmitry Viktorovich Girdyuk, Tatiana Nekhaeva, Natalia Avdonkina, Natalia Viktorovna Emelyanova, Nino Pipia, V. A. Misyurin
Publikováno v:
Clinical Sarcoma Research
Clinical Sarcoma Research, Vol 10, Iss 1, Pp 1-14 (2020)
Clinical Sarcoma Research, Vol 10, Iss 1, Pp 1-14 (2020)
Background Autologous dendritic cells (DC) loaded with tumor-associated antigens (TAAs) are a promising approach for anticancer immunotherapy. Polyantigen lysates appear to be an excellent source of TAAs for loading onto the patient’s dendritic cel
Autor:
Aglaya G. Iyevleva, Yuriy Komarov, Alexey Viktorovich Novik, Alexander Ivantsov, Anna Semenova, Svetlana Protsenko, Evgenii Imianitov, Nino Pipia, Irina Baldueva, Tatiana Semiglazova, Anton Barchuk, Heini Huhtala, Malcolm A.S. Moore, Anna S. Artemyeva, Tatyana Leonidovna Nehaeva
11075 Background: While a number of antigens are known to be expressed in soft tissue sarcomas, little is known about the prognosis of patients with such tumors. Recent data have demonstrated immunologic activity in sarcoma patients expressing the NY
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