Effectiveness of add‐on acetazolamide in children with drug‐resistant CHD2‐related epilepsy and in a zebrafish CHD2 model

Autor: Gia Melikishvili, Pasquale Striano, Elham Shojeinia, Tamar Gachechiladze, Ekaterine Kurua, Nazhi Tabatadze, Mariam Melikishvili, Otar Koniashvili, Gvantsa Khachiashvili, Nino Epitashvili, Gamirova Rimma, Oleg Belyaev, Tatyana Tomenko, Volodymyr Kharytonov, Ulviyya Guliyeva, Camila V. Esguerra, Alexander D. Crawford, Olivier Dulac

Publikováno v: Epilepsia Open, Vol 9, Iss 5, Pp 1972-1980 (2024)

Abstract CHD2‐related epilepsy is characterized by early‐onset photosensitive myoclonic epilepsy with developmental delay and a high rate of pharmacoresistance. We sought to evaluate the efficacy of acetazolamide (ACZ) in CHD2‐related epilepsy,

Externí odkaz: https://doaj.org/article/e5aa511207164ad89a4056dd55618203

Data quality evaluation in wearable monitoring

Autor: Sebastian Böttcher, Solveig Vieluf, Elisa Bruno, Boney Joseph, Nino Epitashvili, Andrea Biondi, Nicolas Zabler, Martin Glasstetter, Matthias Dümpelmann, Kristof Van Laerhoven, Mona Nasseri, Benjamin H. Brinkman, Mark P. Richardson, Andreas Schulze-Bonhage, Tobias Loddenkemper

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)

Abstract Wearable recordings of neurophysiological signals captured from the wrist offer enormous potential for seizure monitoring. Yet, data quality remains one of the most challenging factors that impact data reliability. We suggest a combined data

Externí odkaz: https://doaj.org/article/d4d2f367dc3f422ba120b1c039f07516

Intra- and Inter-Subject Perspectives on the Detection of Focal Onset Motor Seizures in Epilepsy Patients

Autor: Sebastian Böttcher, Elisa Bruno, Nino Epitashvili, Matthias Dümpelmann, Nicolas Zabler, Martin Glasstetter, Valentina Ticcinelli, Sarah Thorpe, Simon Lees, Kristof Van Laerhoven, Mark P. Richardson, Andreas Schulze-Bonhage

Publikováno v: Sensors, Vol 22, Iss 9, p 3318 (2022)

Focal onset epileptic seizures are highly heterogeneous in their clinical manifestations, and a robust seizure detection across patient cohorts has to date not been achieved. Here, we assess and discuss the potential of supervised machine learning mo

Externí odkaz: https://doaj.org/article/806318ae7608462a98e7c8fb279b94c6

Wearable devices for seizure detection: Practical experiences and recommendations from the Wearables for Epilepsy And Research (WEAR) International Study Group

Autor: Elisa Bruno, Mark P. Richardson, Andreas Schulze-Bonhage, Andrea Biondi, Pedro Viana, Matthias Dümpelmann, Sebastian Böttcher, Marta Amengual-Gual, Kristof Van Laerhoven, Boney Joseph, Benjamin H. Brinkmann, Nino Epitashvili, Tobias Loddenkemper, Martin Glasstetter

Publikováno v: Epilepsia
Bruno, E, Böttcher, S, Viana, P F, Amengual-Gual, M, Joseph, B, Epitashvili, N, Dümpelmann, M, Glasstetter, M, Biondi, A, Van Laerhoven, K, Loddenkemper, T, Richardson, M P, Schulze-Bonhage, A & Brinkmann, B H 2021, ' Wearable devices for seizure detection : Practical experiences and recommendations from the Wearables for Epilepsy And Research (WEAR) International Study Group ', Epilepsia, vol. 62, no. 10, pp. 2307-2321 . https://doi.org/10.1111/epi.17044

The Wearables for Epilepsy And Research (WEAR) International Study Group identified a set of methodology standards to guide research on wearable devices for seizure detection. We formed an international consortium of experts from clinical research, e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8fb9c975fa9f4c814d6afc92f5868f
https://doi.org/10.1111/epi.17044

Subcortical band heterotopia in a patient with phenylketonuria: Co-Existence or consequence?

Autor: Dirk-Matthias Altenmüller, Andreas Schulze-Bonhage, Yulia Novitskaya, Horst Urbach, Nino Epitashvili

Publikováno v: Seizure. 86:144-146

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e53733c753f7eeff0f63ccd880951a74
https://doi.org/10.1016/j.seizure.2021.02.016