[68Ga]Ga-Pentixafor PET/CT imaging for in vivo CXCR4 receptor mapping in different lung cancer histologic sub-types: correlation with quantitative receptors’ density by immunochemistry techniques

Autor: Ankit Watts, Baljinder Singh, Harmandeep Singh, Amanjit Bal, Harneet Kaur, Ninjit Dhanota, Sunil K. Arora, Bhagwant R. Mittal, Digambar Behera

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging. 50:1216-1227

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f5ba92bb0dbb3956198950dd1aecb3b
https://doi.org/10.1007/s00259-022-06059-2

Data from Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis

Autor: Samuel F. Bakhoum, Benjamin Izar, Eileen E. Parkes, Alexander N. Shoushtari, Charles Swanton, Olivier Elemento, Jedd D. Wolchok, Simon N. Powell, Neil Vasan, Anusha Kalbasi, Shin-San Michael Su, Nadeem Riaz, Jorge S. Reis-Filho, Hannah Y. Wen, Taha Merghoub, Travis J. Hollmann, Benjamin J. DiPardo, Lee Gottesdiener, Chantal Pauli, Peng Li, Julie-Ann Cavallo, Princesca Dorsaint, Maria Laura Martin, Hao Wei Li, Rohan Bareja, Dhruva Biswas, Ieva Usaite, Kevin Litchfield, Sreeram Vallabhaneni, Johannes C. Melms, Matthew G. Hanna, Jacqueline A. James, Manuel Salto-Tellez, Matthew P. Humphries, Roshan K. Sriram, John Kwon, Sarah E. Bettigole, Walid K. Chatila, Ninjit Dhanota, Mercedes A. Duran, Jun Li

Cytosolic DNA is characteristic of chromosomally unstable metastatic cancer cells, resulting in constitutive activation of the cGAS–STING innate immune pathway. How tumors co-opt inflammatory signaling while evading immune surveillance remains unkn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af51a233154e60a4e2bb2d77e8270d96
https://doi.org/10.1158/2159-8290.c.6549335

Abstract 1330: Role of ENPP1 mediated extracellular cGAMP hydrolysis in cancer metastasis and immune evasion

Autor: John Young Ho Kwon, Jun Li, Mercedes Duran, Ninjit Dhanota, Samuel Bakhoum

Publikováno v: Cancer Research. 82:1330-1330

Chromosome instability (CIN) promotes metastasis through sustained tumor-cell autonomous response to cytosolic DNA. Chromosome mis-segregation engenders the formation of micronuclei, which upon rupture chronically activates the cGAS-STING DNA sensing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb4ccc2ac9daa5d968b3742f6b205484
https://doi.org/10.1158/1538-7445.am2022-1330

Metastasis and immune evasion from extracellular cGAMP hydrolysis

Autor: Mercedes Duran, Princesca Dorsaint, Julie-Ann Cavallo, Shin-San Michael Su, Dhruva Biswas, Taha Merghoub, Maria Laura Martin, Sreeram Vallabhaneni, Simon N. Powell, Manuel Salto-Tellez, Jedd D. Wolchok, Neil Vasan, Anusha Kalbasi, Nadeem Riaz, Hannah Y Wen, Samuel F. Bakhoum, Jun Li, Benjamin J DiPardo, Jacqueline James, Charles Swanton, Lee S. Gottesdiener, Olivier Elemento, John Kwon, Benjamin Izar, Alexander N. Shoushtari, Rohan Bareja, Hao Wei Li, Matthew G. Hanna, Johannes C. Melms, Ieva Usaite, Kevin Litchfield, Ninjit Dhanota, Matthew P. Humphries, Eileen Parkes, Travis J Hollmann, Roshan K. Sriram, Chantal Pauli, Sarah E Bettigole, Jorge S. Reis-Filho, Peng Li, Walid K. Chatila

Publikováno v: Li, J, Duran, M A, Dhanota, N, Chatila, W K, Bettigole, S E, Kwon, J, Sriram, R K, Humphries, M P, Salto-Tellez, M, James, J A, Hanna, M G, Melms, J C, Vallabhaneni, S, Litchfield, K, Usaite, I, Biswas, D, Bareja, R, Li, H W, Martin, M L, Dorsaint, P, Cavallo, J-A, Li, P, Pauli, C, Gottesdiener, L, DiPardo, B J, Hollmann, T J, Merghoub, T, Wen, H Y, Reis-Filho, J S, Riaz, N, Su, S-S M, Kalbasi, A, Vasan, N, Powell, S N, Wolchok, J D, Elemento, O, Swanton, C, Shoushtari, A N, Parkes, E E, Izar, B & Bakhoum, S F 2020, ' Metastasis and immune evasion from extracellular cGAMP hydrolysis ', Cancer discovery, vol. Early Online, pp. xx . https://doi.org/10.1158/2159-8290.CD-20-0387
Cancer Discov

Cytosolic DNA is characteristic of chromosomally unstable metastatic cancer cells, resulting in constitutive activation of the cGAS–STING innate immune pathway. How tumors co-opt inflammatory signaling while evading immune surveillance remains unkn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3a80cefbaee3bdab1ee35690a87c04
https://pure.qub.ac.uk/en/publications/metastasis-and-immune-evasion-from-extracellular-cgamp-hydrolysis(6d7c17ea-11d5-406d-8d68-1f1010b32751).html