Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ninitha Asirvatham-Jeyaraj"'
Autor:
Sneha Mishra, Claudia Cosentino, Ankit Kumar Tamta, Danish Khan, Shalini Srinivasan, Venkatraman Ravi, Elena Abbotto, Bangalore Prabhashankar Arathi, Shweta Kumar, Aditi Jain, Anand S. Ramaian, Shruti M. Kizkekra, Raksha Rajagopal, Swathi Rao, Swati Krishna, Ninitha Asirvatham-Jeyaraj, Elizabeth R. Haggerty, Dafne M. Silberman, Irwin J. Kurland, Ravindra P. Veeranna, Tamilselvan Jayavelu, Santina Bruzzone, Raul Mostoslavsky, Nagalingam R. Sundaresan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Chronic stress induces skeletal muscle atrophy via upregulation of glucocorticoid levels. Here, the authors show that SIRT6 transcriptionally regulates glucocorticoid-induced muscle atrophy by modulating IGF/PI3K/AKT signalling.
Externí odkaz:
https://doaj.org/article/d4cbf3bac7a14798ba51e0d8aeaeb195
Autor:
Mia Larson, Daniel P. Chantigian, Ninitha Asirvatham-Jeyaraj, Ann Van de Winckel, Manda L. Keller-Ross
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Purpose: To determine if acute slow breathing at 6 breaths/min would improve baroreflex sensitivity (BRS) and heart rate variability (HRV), and lower blood pressure (BP) in adults after stroke.Methods: Twelve individuals completed two randomized stud
Externí odkaz:
https://doaj.org/article/cdb92e0aa00f4a0684a68e25d040aa31
Autor:
Ninitha Asirvatham-Jeyaraj, Raisa Monteiro, Delton Hall, Mahesh Kumar Sivasubramanian, Madhan Subramanian, Priya Balasubramanian
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Increases in sympathetic nerve activity (SNA) have been implicated in obesity-induced risk for cardiovascular diseases, especially hypertension. Previous studies indicate that oxidative stress in the rostral ventrolateral medulla (RVLM), a key brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe4e1f1244aeef9027ff711cfe9b17b
https://doi.org/10.1152/ajpregu.00206.2019
https://doi.org/10.1152/ajpregu.00206.2019
Publikováno v:
Hypertension. 74:1499-1506
This study tested whether brain L-PGDS (lipocalin-type prostaglandin [PG] D synthase), through prostanoid signaling, might increase neurogenic pressor activity and thereby cause hypertension. Sprague Dawley rats on high-salt diet received either vehi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b9c2a8d4105fe5fcc48c456bba05b3
https://doi.org/10.1161/hypertensionaha.119.13175
https://doi.org/10.1161/hypertensionaha.119.13175
Autor:
Madeline M. Gauthier, Hannah Garver, Abhismitha Ramesh, Christopher T. Banek, John W. Osborn, Ninitha Asirvatham-Jeyaraj, Gregory D. Fink
Publikováno v:
Hypertension (Dallas, Tex. : 1979)
Supplemental Digital Content is available in the text.
Renal denervation (RDNX) lowers mean arterial pressure (MAP) in patients with resistant hypertension. Less well studied is the effect of celiac ganglionectomy (CGX), a procedure which involv
Renal denervation (RDNX) lowers mean arterial pressure (MAP) in patients with resistant hypertension. Less well studied is the effect of celiac ganglionectomy (CGX), a procedure which involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e27af0351ef9151d8e102690053adf
https://pubmed.ncbi.nlm.nih.gov/33390041
https://pubmed.ncbi.nlm.nih.gov/33390041
Autor:
Christopher T. Banek, Daniel C. Baumann, Dusty Van Helden, Ninitha Asirvatham-Jeyaraj, Gregory D. Fink, Angela Panoskaltsis-Mortari, John W. Osborn, Madeline M. Gauthier
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 314:R883-R891
Recent preclinical studies show renal denervation (RDNx) may be an effective treatment for hypertension; however, the mechanism remains unknown. We have recently reported total RDNx (TRDNx) and afferent-selective RDNx (ARDNx) similarly attenuated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b846e0ca094b1798b21a795e5db60239
https://doi.org/10.1152/ajpregu.00416.2017
https://doi.org/10.1152/ajpregu.00416.2017
Autor:
Kathryn Vera, Mia Larson, Daniel P. Chantigian, Manda L. Keller-Ross, Ninitha Asirvatham-Jeyaraj, Emma J. Lee
Publikováno v:
Respir Physiol Neurobiol
Estrogen can reduce sympathetic activity, but its effects on minute ventilation (V(E)) with group III/IV afferent activation remain unclear. This study examined the influence of estrogen on V(E) during lower-extremity exercise with group III/IV activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033cc9624c973f8ec2e16414b1d0d729
https://doi.org/10.1016/j.resp.2021.103712
https://doi.org/10.1016/j.resp.2021.103712
Autor:
Ninitha Asirvatham-Jeyaraj, Yoji Shimizu, Christopher T. Banek, Dusty Van Helden, Jessica K. Fiege, Mark M. Knuepfer, John W. Osborn, Jason D. Foss
Publikováno v:
Hypertension. 68:1415-1423
Renal sympathetic denervation (RDNx) has emerged as a novel therapy for hypertension; however, the therapeutic mechanisms remain unclear. Efferent renal sympathetic nerve activity has recently been implicated in trafficking renal inflammatory immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b392890bf1288db4215cbc9370b06287
https://doi.org/10.1161/hypertensionaha.116.07850
https://doi.org/10.1161/hypertensionaha.116.07850
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd3b18decf801ff423518269c975b992
https://doi.org/10.1096/fasebj.2019.33.1_supplement.563.2
https://doi.org/10.1096/fasebj.2019.33.1_supplement.563.2
Autor:
Edward A Gonzalez, Jayadevan Parvathy, Raul Mostoslavsky, Subhajit Dasgupta, Ninitha Asirvatham-Jeyaraj, Danish Khan, Jean-Pierre Etchegaray, Raksha Rajagopal, Venkatraman Ravi, Nagalingam R. Sundaresan, Ankit Kumar Tamta, Himani Tandon, Sneha Mishra, Prasanna Simha Mohan Rao, Arvind Singh Bhati, Ullas Kolthur-Seetharam, Tarannum Ara, Swati Krishna, Narayanaswamy Srinivasan, Sukanya Raghu
Publikováno v:
Cell reports
SUMMARY Pathological lipid accumulation is often associated with enhanced uptake of free fatty acids via specific transporters in cardiomyocytes. Here, we identify SIRT6 as a critical transcriptional regulator of fatty acid transporters in cardiomyoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e21d71a7ba00b2b61c76a9104b2a5ed
http://europepmc.org/articles/PMC8190874
http://europepmc.org/articles/PMC8190874