Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Ningshan Liu"'
Autor:
Jiurong Liang, Guanling Huang, Xue Liu, Ningshan Liu, Forough Taghavifar, Kristy Dai, Changfu Yao, Nan Deng, Yizhou Wang, Peter Chen, Cory Hogaboam, Barry R Stripp, William C Parks, Paul W Noble, Dianhua Jiang
Publikováno v:
eLife, Vol 12 (2023)
Aging is a critical risk factor in idiopathic pulmonary fibrosis (IPF). Dysfunction and loss of type 2 alveolar epithelial cells (AEC2s) with failed regeneration is a seminal causal event in the pathogenesis of IPF, although the precise mechanisms fo
Externí odkaz:
https://doaj.org/article/dc36e141f9de42bfa03fa5b279b8212e
Autor:
Jiurong Liang, Guanling Huang, Xue Liu, Forough Taghavifar, Ningshan Liu, Yizhou Wang, Nan Deng, Changfu Yao, Ting Xie, Vrishika Kulur, Kristy Dai, Ankita Burman, Simon C. Rowan, S. Samuel Weigt, John Belperio, Barry Stripp, William C. Parks, Dianhua Jiang, Paul W. Noble
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 11 (2022)
Type 2 alveolar epithelial cells (AEC2s) function as progenitor cells in the lung. We have shown previously that failure of AEC2 regeneration results in progressive lung fibrosis in mice and is a cardinal feature of idiopathic pulmonary fibrosis (IPF
Externí odkaz:
https://doaj.org/article/f7539cbaaa2b4928beaa1bce4118eb7f
Autor:
Ting Xie, Yizhou Wang, Nan Deng, Guanling Huang, Forough Taghavifar, Yan Geng, Ningshan Liu, Vrishika Kulur, Changfu Yao, Peter Chen, Zhengqiu Liu, Barry Stripp, Jie Tang, Jiurong Liang, Paul W. Noble, Dianhua Jiang
Publikováno v:
Cell Reports, Vol 22, Iss 13, Pp 3625-3640 (2018)
Summary: Fibroblast heterogeneity has long been recognized in mouse and human lungs, homeostasis, and disease states. However, there is no common consensus on fibroblast subtypes, lineages, biological properties, signaling, and plasticity, which seve
Externí odkaz:
https://doaj.org/article/edd0b2cb8e314760a43c4107059cc9fc
Autor:
Guanling Huang, Jiurong Liang, Kevin Huang, Xue Liu, Forough Taghavifar, Changfu Yao, Tanyalak Parimon, Ningshan Liu, Kristy Dai, Adam Aziz, Yizhou Wang, Richard T. Waldron, Hongmei Mou, Barry Stripp, Paul W. Noble, Dianhua Jiang
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 68:302-313
Loss of epithelial integrity, bronchiolarization, and fibroblast activation are key characteristics of idiopathic pulmonary fibrosis (IPF). Prolonged accumulation of basal-like cells in IPF may impact the fibrotic niche to promote fibrogenesis. To in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f736dcf184de24cd2d7f77371f36aba
https://doi.org/10.1165/rcmb.2022-0074oc
https://doi.org/10.1165/rcmb.2022-0074oc
Autor:
Xue Liu, Yan Geng, Jiurong Liang, Ana Lucia Coelho, Changfu Yao, Nan Deng, Yizhou Wang, Kristy Dai, Guanling Huang, Ting Xie, Ningshan Liu, Simon C. Rowan, Forough Taghavifar, Vrishika Kulur, Zhenqiu Liu, Barry R. Stripp, Cory M. Hogaboam, Dianhua Jiang, Paul W. Noble
Publikováno v:
The Journal of experimental medicine. 219(10)
Progressive tissue fibrosis, including idiopathic pulmonary fibrosis (IPF), is characterized by excessive recruitment of fibroblasts to sites of tissue injury and unremitting extracellular matrix deposition associated with severe morbidity and mortal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b84dcedcbb532989fe30947623c98a8
https://pubmed.ncbi.nlm.nih.gov/35980387
https://pubmed.ncbi.nlm.nih.gov/35980387
Autor:
Simon C. Rowan, Vrishika Kulur, Ningshan Liu, Nan Deng, Cory M. Hogaboam, Guanling Huang, Xue Liu, Peter Chen, Jiurong Liang, Barry R. Stripp, Changfu Yao, Dianhua Jiang, Yizhou Wang, Forough Taghavifar, Paul W. Noble, Ting Xie
Publikováno v:
Science Advances
Mesenchymal vesicular GHR supports alveolar epithelial progenitor cell renewal and limits lung fibrosis.
Recent studies have identified impaired type 2 alveolar epithelial cell (ATII) renewal in idiopathic pulmonary fibrosis (IPF) human organoid
Recent studies have identified impaired type 2 alveolar epithelial cell (ATII) renewal in idiopathic pulmonary fibrosis (IPF) human organoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0163dfcabc50c218b6b729fa97ba98ee
https://zenodo.org/record/5228490
https://zenodo.org/record/5228490
Autor:
Simon C. Rowan, S. Samuel Weigt, Yizhou Wang, Barry R. Stripp, John A. Belperio, Ankita Burman, Dianhua Jiang, Forough Taghavifar, Xue Liu, William C. Parks, Paul W. Noble, Changfu Yao, Nan Deng, Ting Xie, Jiurong Liang, Ningshan Liu, Guanling Huang
SUMMARY Idiopathic pulmonary fibrosis (IPF) is a fatal form of interstitial lung disease and aging has been identified as a risk factor to the disease. Alveolar type II cells (AEC2s) function as progenitor cells in the lung. Growing evidences indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::848b6cc4397e30075518fd6eb24aa71b
https://doi.org/10.1101/2020.07.30.229567
https://doi.org/10.1101/2020.07.30.229567
Autor:
William C. Parks, Ankita Burman, Simon C. Rowan, Changfu Yao, Nan Deng, Yizhou Wang, John A. Belperio, Barry R. Stripp, Paul W. Noble, Cory M. Hogaboam, Guanling Huang, Ningshan Liu, S. Samuel Weigt, Dianhua Jiang, Forough Taghavifar, Xue Liu, Peter Chen, Ting Xie, Jiurong Liang
Aging is a critical risk factor in progressive lung fibrotic diseases such as idiopathic pulmonary fibrosis (IPF). Loss of integrity of type 2 alveolar epithelial cells (AEC2s) is the main causal event in the pathogenesis of IPF. To systematically ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb1fd518cec39c6ca9fb173b5de125b3
https://doi.org/10.1101/2020.07.30.227892
https://doi.org/10.1101/2020.07.30.227892
Autor:
Vrishika Kulur, Ting Xie, Paul W. Noble, Xue Liu, Ningshan Liu, Dianhua Jiang, C. Huan, Guanling Huang, Yan Geng, C.J. Liang
Publikováno v:
A62. LUNG FIBROSIS: INSIGHTS FROM THE BENCH.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9503da6125f10ac6c90151f8757845ea
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2234
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2234
Autor:
Vrishika Kulur, Yizhou Wang, Yan Geng, Nan Deng, Jiurong Liang, Ningshan Liu, Zhengqiu Liu, Changfu Yao, Jie Tang, Barry R. Stripp, Dianhua Jiang, Forough Taghavifar, Paul W. Noble, Ting Xie, Guanling Huang, Peter Chen
Publikováno v:
Cell reports
Cell Reports, Vol 22, Iss 13, Pp 3625-3640 (2018)
Cell Reports, Vol 22, Iss 13, Pp 3625-3640 (2018)
SUMMARY Fibroblast heterogeneity has long been recognized in mouse and human lungs, homeostasis, and disease states. However, there is no common consensus on fibroblast subtypes, lineages, biological properties, signaling, and plasticity, which sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4deda23b3547fb69a4bddde0c36fff66
http://europepmc.org/articles/PMC5908225
http://europepmc.org/articles/PMC5908225