Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ningning Zhuang"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Extra-cytoplasmic function (ECF) σ factors allow bacteria to rapidly respond to stress conditions. Here the authors provide insights into the mechanism of bacterial stress-induced transcription by determining the crystal structures of the M. tubercu
Externí odkaz:
https://doaj.org/article/1a58aa4b88894a5ead7026afa2e00b8e
Autor:
Amar A Telke, Ningning Zhuang, Sunil S Ghatge, Sook-Hee Lee, Asad Ali Shah, Haji Khan, Youngsoon Um, Hyun-Dong Shin, Young Ryun Chung, Kon Ho Lee, Seon-Won Kim
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65727 (2013)
Cel5A, an endoglucanase, was derived from the metagenomic library of vermicompost. The deduced amino acid sequence of Cel5A shows high sequence homology with family-5 glycoside hydrolases, which contain a single catalytic domain but no distinct cellu
Externí odkaz:
https://doaj.org/article/ae46e70a6a754314a428a97fe2a0f97a
Publikováno v:
J Biol Chem
A recently discovered ornithine-ammonia cycle (OAC) serves as a conduit in the nitrogen storage and remobilization machinery in cyanobacteria. The OAC involves an arginine catabolic reaction catalyzed by the arginine dihydrolase ArgZ whose catalytic
Autor:
Xiaoxian Wu, Yue J. Liu, Ningning Zhuang, Liqiang Shen, Allen G. Sanderlin, Diane Laure Haakonsen, Michael T. Laub, Yu Zhang
Publikováno v:
Nucleic Acids Research
Canonical bacterial transcription activators bind to non-transcribed promoter elements to increase transcription of their target genes. Here we report crystal structures of binary complexes comprising domains of Caulobacter crescentus GcrA, a noncano
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Bacterial RNA polymerase employs extra-cytoplasmic function (ECF) σ factors to regulate context-specific gene expression programs. Despite being the most abundant and divergent σ factor class, the structural basis of ECF σ factor-mediated transcri
Autor:
Pengcheng Han, Jiong Shi, Thomas G. Beach, Geidy E. Serrano, Richard J. Caselli, Ningning Zhuang, Junxiang Yin
Publikováno v:
Journal of neuropathology and experimental neurology. 76(1)
Neurofibrillary tangles (NFTs) represent products of insoluble tau protein in the brains of patients with Alzheimer disease (AD). The cerebrospinal fluid (CSF) tau level is a biomarker in AD diagnosis. The soluble portion of tau protein in brain pare
Autor:
Ki Hun Park, Heung Joo Yuk, Dae Wook Kim, Kon Ho Lee, Yan Wang, Yeong Hun Song, Marcus J. Curtis-Long, Kwon Seok Jeon, Ningning Zhuang
Publikováno v:
Biological and Pharmaceutical Bulletin. 37:1021-1028
Tribulus terrestris fruits are well known for their usage in pharmaceutical preparations and food supplements. The methanol extract of T. terrestris fruits showed potent inhibition against the papain-like protease (PLpro), an essential proteolylic en
Autor:
Ningning Zhuang1, Hao Zhang1,2, Lingting Li1,2, Xiaoxian Wu1,2, Chen Yang1 chenyang@sibs.ac.cn, Yu Zhang1 yzhang@sippe.ac.cn
Publikováno v:
Journal of Biological Chemistry. 2/14/2020, Vol. 295 Issue 7, p2113-2124. 12p.
Publikováno v:
Alzheimer's & Dementia. 12
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 68:1560-1563
Mevalonate kinase (MVK), which plays an important role in catalysing the biosynthesis of isoprenoid compounds derived from the mevalonate pathway, transforms mevalonate to 5-phosphomevalonate using ATP as a cofactor. Mevalonate kinase from Methanosar