Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ningli Zhang"'
Autor:
Tao Shi, Jianping Yang, Ningli Zhang, Wei Rong, Lusha Gao, Ping Xia, Jie Zou, Na Zhu, Fazhi Yang, Lixing Chen
Publikováno v:
Digital Health, Vol 10 (2024)
Objective Explainable machine learning (XAI) was introduced in this study to improve the interpretability, explainability and transparency of the modelling results. The survex package in R was used to interpret and compare two survival models – the
Externí odkaz:
https://doaj.org/article/3facce18e5774a0d8a0a3805eb655bc1
Autor:
Jennifer M. Thorn, Keshab Bhattacharya, Renata Crutcher, Justin Sperry, Colleen Isele, Barbara Kelly, Libbey Yates, James Zobel, Ningli Zhang, Heather L. Davis, Michael J. McCluskie
Publikováno v:
Vaccines, Vol 5, Iss 2, p 11 (2017)
Smoking remains one of the major causes of morbidity and mortality worldwide. One approach to assisting smoking cessation is via anti-nicotine vaccines, composed of nicotine-like haptens conjugated to a carrier protein plus adjuvant(s). We have previ
Externí odkaz:
https://doaj.org/article/c9bde9921e754ec989c485e11d57098d
Autor:
David C Pryde, Lyn H Jones, David P Gervais, David R Stead, David C Blakemore, Matthew D Selby, Alan D Brown, Jotham W Coe, Matthew Badland, David M Beal, Rebecca Glen, Yvonne Wharton, Gavin J Miller, Phil White, Ningli Zhang, Michelle Benoit, Karen Robertson, James R Merson, Heather L Davis, Michael J McCluskie
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76557 (2013)
Anti-nicotine vaccines may aid smoking cessation via the induction of anti-nicotine antibodies (Ab) which reduce nicotine entering the brain, and hence the associated reward. Ab function depends on both the quantity (titer) and the quality (affinity)
Externí odkaz:
https://doaj.org/article/d241124036e24c84ac8c79ff70c995d1
Autor:
James F. Zobel, Libbey Anne Yates, Jennifer Marie Thorn, Colleen Isele, Michael J. McCluskie, Keshab Bhattacharya, Justin B. Sperry, Renata Crutcher, Barbara Kelly, Ningli Zhang, Heather L. Davis
Publikováno v:
Vaccines, Vol 5, Iss 2, p 11 (2017)
Vaccines
Vaccines
Smoking remains one of the major causes of morbidity and mortality worldwide. One approach to assisting smoking cessation is via anti-nicotine vaccines, composed of nicotine-like haptens conjugated to a carrier protein plus adjuvant(s). We have previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf063813eeefd5f8db5218cbd5ada0af
http://www.mdpi.com/2076-393X/5/2/11
http://www.mdpi.com/2076-393X/5/2/11
Autor:
James R. Merson, Lianchun Chen, In-Jeong Kim, Daisy Hammond, Clare Christy, Tharsika Tharmanathan, R. Brad Jones, Heather A. Simmons, Mario A. Ostrowski, Kerry A Beheler, Eva G. Rakasz, Jakir Hussain Ullah, Neil C. Sheppard, Carla Fernandes, Dusko Trajkovic, Peter T. Loudon, Douglas F. Nixon, Jonah B. Sacha, Philip A. Castrovinci, Jason S. Reed, Melanie Rieger, Patrick B. Lappin, Ingrid M. Pruimboom-Brees, Daniel Schenkman, Juliann Janies, Ningli Zhang, Joseph P. Gardner, Sing Rong, Douglas H Gebhard, Ahmed M. Shoieb, Michael J. McCluskie, Shari M. Piaskowski, Klaus Rumpel, Laura Newman, Francesca A. Nimityongskul, Robert J Gifford, Brian G. Pierce, Frederike von Pelchrzim, David A. Goodwin, Sophie Muscat-King, Samantha E. Wildeboer
Publikováno v:
The Journal of Immunology. 189:1467-1479
The expression of endogenous retrotransposable elements, including long interspersed nuclear element 1 (LINE-1 or L1) and human endogenous retrovirus, accompanies neoplastic transformation and infection with viruses such as HIV. The ability to engend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7367f62dea46e68bcbd19dc7596b7d1
https://doi.org/10.4049/jimmunol.1200079
https://doi.org/10.4049/jimmunol.1200079
Publikováno v:
Proceedings 2013 International Conference on Mechatronic Sciences, Electric Engineering & Computer (MEC); 2013, p10-14, 5p
Publikováno v:
Infection and Immunity. 74:1944-1948
Treatment with an oligodeoxynucleotide (ODN) containing CPG motifs (CpG ODN 7909) was found to protect BALB/c mice from lung infection or death after aerosol challenge withBurkholderia mallei. Protection was associated with enhanced levels of gamma i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46dd27b91b53896620588eb8371421f3
https://doi.org/10.1128/iai.74.3.1944-1948.2006
https://doi.org/10.1128/iai.74.3.1944-1948.2006
Autor:
Keshab Bhattacharya, Jennifer Marie Thorn, Michael J. McCluskie, Ghania Chikh, Jari I. Finneman, Dana M. Evans, Ningli Zhang, Heather L. Davis, James R. Merson, Paul Robert Mehelic, David Robert Stead, Michele Bailey Piatchek, Janna Cartier, Parag Kolhe
Publikováno v:
International immunopharmacology. 25(2)
Anti-nicotine vaccines aim to prevent nicotine entering the brain, and thus reduce or eliminate the reward that drives nicotine addiction. Those tested in humans to date have failed to improve quit rates over placebo, possibly because antibody (Ab) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f927cafb6fa8190aeb42bfc93f4eb5
https://pubmed.ncbi.nlm.nih.gov/25737198
https://pubmed.ncbi.nlm.nih.gov/25737198
Autor:
Michael J. McCluskie, Michelle Benoit, David Robert Stead, Ningli Zhang, Heather L. Davis, David C. Pryde, James R. Merson, Karen Robertson, David Gervais, Tharsika Tharmanathan, In-Jeong Kim
Publikováno v:
International immunopharmacology. 16(1)
Tobacco smoking is one of the most preventable causes of morbidity and mortality, but current smoking cessation treatments have relatively poor long term efficacy. Anti-nicotine vaccines offer a novel mechanism of action whereby anti-nicotine antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecee2ecd07d6c12fbba9ad34a7a9055d
https://pubmed.ncbi.nlm.nih.gov/23562759
https://pubmed.ncbi.nlm.nih.gov/23562759
Autor:
Rachel Luu, Alain Vicari, Ningli Zhang, Shawn R. Makinen, Risini D. Weeratna, Douglas C. Hanson, Shobhna Patel, Arthur M. Krieg
Publikováno v:
Cancer immunology, immunotherapy : CII. 58(4)
The anti-tumor properties of Toll-like receptor (TLR) 9 agonist CpG oligodeoxynucleotides (ODN) are enhanced by combinations with several cytotoxic chemotherapy regimens. The mechanisms of this added benefit, however, remain unclear. We now report th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2013a7c653fffa93bd8ba6aea8106dbd
https://pubmed.ncbi.nlm.nih.gov/18802696
https://pubmed.ncbi.nlm.nih.gov/18802696