Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ninghui Ma"'
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The clinical use of Polygonum multiflorum Thunb (PM) has been restricted or banned in many countries, due to its hepatotoxic adverse effects. Its toxicity research has become a hot topic. So far, the pharmacokinetic studies of PM, focusing on prototy
Externí odkaz:
https://doaj.org/article/74da450b2fed4dc7a6b42c714781658f
Publikováno v:
Molecules, Vol 23, Iss 9, p 2214 (2018)
To rapidly clarify and quantify the chemical profiling of Cinnamomi cortex a reliable and feasible strategy of chromatographic fingerprinting with a suite of chemometrics methods was developed and validated by ultra-high performance liquid chromatogr
Externí odkaz:
https://doaj.org/article/22c53b2804d648e2a0a3a34c05cd23e4
Autor:
Sherly I. Celada, Guoliang Li, Lindsay J. Celada, Wenfu Lu, Thanigaivelan Kanagasabai, Weiran Feng, Zhen Cao, Nazifa Salsabeel, Ninghui Mao, LaKendria K. Brown, Zaniya A. Mark, Michael G. Izban, Billy R. Ballard, Xinchun Zhou, Samuel E. Adunyah, Robert J. Matusik, Xiaofei Wang, Zhenbang Chen
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2126-2146 (2023)
Changes in FOXA1 (forkhead box protein A1) protein levels are well associated with prostate cancer (PCa) progression. Unfortunately, direct targeting of FOXA1 in progressive PCa remains challenging due to variations in FOXA1 protein levels, increased
Externí odkaz:
https://doaj.org/article/0cac8103e1024d5d960e34525c1fc17d
Autor:
Ninghui Mao, Zeda Zhang, Young Sun Lee, Danielle Choi, Aura Agudelo Rivera, Dan Li, Cindy Lee, Samuel Haywood, Xiaoping Chen, Qing Chang, Guotai Xu, Hsuan-An Chen, Elisa de Stanchina, Charles Sawyers, Neal Rosen, Andrew C. Hsieh, Yu Chen, Brett S. Carver
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Understanding the mechanisms driving PI3K isoform dependency in prostate cancer can help the design of future clinical trials. Here, the authors show that gain-of-function mutations in PIK3CA or PIK3CB can confer PI3K p110 isoform dependency and that
Externí odkaz:
https://doaj.org/article/907e2e85e15748fa85c06a824495c169
Autor:
Haley Hieronymus, Phillip J. Iaquinta, John Wongvipat, Anuradha Gopalan, Rajmohan Murali, Ninghui Mao, Brett S. Carver, Charles L. Sawyers
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Although the locus at 3p13-14 is commonly deleted in prostate cancer, the identity of the potential driver genes is still unclear. Here, the authors, using a PTEN loss-driven prostate cancer mouse model, show that a multigenic FOXP1-SHQ1 deletion is
Externí odkaz:
https://doaj.org/article/836ceacd80084e6394c47fe1007f64e2
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003145 (2013)
The telomere-ending binding protein complex CST (Cdc13-Stn1-Ten1) mediates critical functions in both telomere protection and replication. We devised a co-expression and affinity purification strategy for isolating large quantities of the complete Ca
Externí odkaz:
https://doaj.org/article/9a6f03101a044b55859f557f35b79a2a