Výsledky vyhledávání - "Ningdi F Liu"

NMR in integrated biophysical drug discovery for RAS: past, present, and future

Autor: Teklab Gebregiworgis, Christopher B. Marshall, Fenneke KleinJan, Geneviève M.C. Gasmi-Seabrook, Ben J Eves, Masahiro Enomoto, Ningdi F Liu, Ki-Young Lee, Mitsuhiko Ikura, Zhenhao Fang

Publikováno v: Journal of Biomolecular NMR. 74:531-554

Mutations in RAS oncogenes occur in ~ 30% of human cancers, with KRAS being the most frequently altered isoform. RAS proteins comprise a conserved GTPase domain and a C-terminal lipid-modified tail that is unique to each isoform. The GTPase domain is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fef215478b276d4d293ad38a5ad0b6
https://doi.org/10.1007/s10858-020-00338-6

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