Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Ning-Jiun Jan"'
Autor:
Rebecca Pierce, Ning-Jiun Jan, Pankaj Kumar, Jeremy Middleton, William A. Petri, Chelsea Marie
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Crohn’s disease is an inflammatory condition of the intestine characterized by largely unknown etiology and a relapse remission cycle of disease control. While possible triggers have been identified, research is inconsistent on the precise
Externí odkaz:
https://doaj.org/article/d1c44eade98d4b309d9737af86d024bb
Autor:
Rebecca M. Munday, Rashidul Haque, Ning-Jiun Jan, Genevieve L. Wojcik, Chelsea Marie, Dylan Duchen, Alexander J. Mentzer, Uma Nayak, Poonum Korpe, Beth D. Kirkpatrick, William A. Petri, Priya Duggal
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Diarrhea is responsible for the deaths of more than 500,000 children each year, many of whom reside in low-to-middle-income countries (LMICs). Additionally, children with multiple diarrheal infections early in life have increased growth stun
Externí odkaz:
https://doaj.org/article/87b8d59df7c745c6bc60e3494ea5b1c0
Autor:
Bo Wang, Huong Tran, Matthew A Smith, Tigran Kostanyan, Samantha E Schmitt, Richard A Bilonick, Ning-Jiun Jan, Larry Kagemann, Elizabeth C Tyler-Kabara, Hiroshi Ishikawa, Joel S Schuman, Ian A Sigal, Gadi Wollstein
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188302 (2017)
There is increasing clinical evidence that the eye is not only affected by intraocular pressure (IOP), but also by intracranial pressure (ICP). Both pressures meet at the optic nerve head of the eye, specifically the lamina cribrosa (LC). The LC is a
Externí odkaz:
https://doaj.org/article/d84f3561887c49ed8a43a6805aa96d70
Autor:
Ning-Jiun Jan, Po-Yi Lee, Jacob Wallace, Michael Iasella, Alexandra Gogola, Bingrui Wang, Ian A. Sigal
Publikováno v:
Journal of Biomechanical Engineering. 145
Stretch-induced collagen uncrimping underlies the nonlinear mechanical behavior of the sclera according to what is often called the process of recruitment. We recently reported experimental measurements of sclera collagen crimp and pressure-induced u
Autor:
William A. Petri, Ning-Jiun Jan, Chelsea Marie, Pankaj Kumar, Brian W Behm, Noah Oakland, Girija Ramakrishnan
BackgroundClostridioides difficile infection (CDI) is the most common hospital-acquired infection in the United States. Antibiotic-induced dysbiosis is the primary cause of susceptibility and fecal microbiota transplantation (FMT) has emerged as an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d705b719ea5739d853a35a946d03aa9b
https://doi.org/10.1101/2021.07.16.21260643
https://doi.org/10.1101/2021.07.16.21260643
Autor:
Ning-Jiun Jan, Joel S. Schuman, Andrew P. Voorhees, Bingrui Wang, Yi Hua, Ian A. Sigal, Susannah Waxman
Publikováno v:
Exp Eye Res
Collagen fibers organized circumferentially around the canal in the peripapillary sclera are thought to provide biomechanical support to the sensitive tissues within the optic nerve head (ONH). Recent studies have demonstrated the existence of a fami
Autor:
Ian A. Sigal, Ning-Jiun Jan
Publikováno v:
Acta Biomaterialia. 72:295-305
Our goal was to quantify and characterize how the collagen fiber crimp waviness of the lamina cribrosa (LC) and peripapillary sclera (PPS) changes with intraocular pressure (IOP). Thirteen sheep (ovine) eyes were immersion and perfusion fixed while m
Publikováno v:
Acta Biomaterialia. 58:278-290
It is widely considered that intraocular pressure (IOP)-induced deformation within the neural tissue pores of the lamina cribrosa (LC) contributes to neurodegeneration and glaucoma. Our goal was to study how the LC microstructure and mechanical prope
Autor:
Andrew P. Voorhees, Ian A. Sigal, Yolandi van der Merwe, Kevin C. Chan, Ning-Jiun Jan, Huong Tran, Leon C. Ho
Publikováno v:
Experimental Eye Research. 160:85-95
The eye is a complex structure composed of several interconnected tissues acting together, across the whole globe, to resist deformation due to intraocular pressure (IOP). However, most work in the ocular biomechanics field only examines the response
Autor:
John G. Flanagan, Ian A. Sigal, Morgan E. Austin, Ning-Jiun Jan, Richard A. Bilonick, Andrew P. Voorhees, Jeremy M Sivak
Publikováno v:
Investigative Ophthalmology & Visual Science
Investigative ophthalmology & visual science, vol 58, iss 12
Investigative ophthalmology & visual science, vol 58, iss 12
Author(s): Voorhees, Andrew P; Jan, Ning-Jiun; Austin, Morgan E; Flanagan, John G; Sivak, Jeremy M; Bilonick, Richard A; Sigal, Ian A | Abstract: PurposeThe purpose of this study was to determine how the architecture of the lamina cribrosa (LC) micro