Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Ning Tsao"'
Autor:
Lingzhen Kong, Chen Cheng, Abigael Cheruiyot, Jiayi Yuan, Yichan Yang, Sydney Hwang, Daniel Foust, Ning Tsao, Emily Wilkerson, Nima Mosammaparast, Michael B. Major, David W. Piston, Shan Li, Zhongsheng You
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The protection of the replication fork structure under stress conditions is essential for genome maintenance and cancer prevention. A key signaling pathway for fork protection involves TRPV2-mediated Ca2+ release from the ER, which is trigge
Externí odkaz:
https://doaj.org/article/0f9d4eec787842fb898dc9fb70b2dd44
Autor:
Junqiao Jia, Tarek Hilal, Katherine E. Bohnsack, Aleksandar Chernev, Ning Tsao, Juliane Bethmann, Aruna Arumugam, Lane Parmely, Nicole Holton, Bernhard Loll, Nima Mosammaparast, Markus T. Bohnsack, Henning Urlaub, Markus C. Wahl
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
ASCC3 is a multi-functional helicase that contains two consecutive Ski2-like helicase units. Here, the authors show that ASCC3 can unwind DNA by threading one strand of a substrate duplex through both helicase units, supported by the TRIP4 protein.
Externí odkaz:
https://doaj.org/article/0ee2586a4c9f44dfb7f3b09d1b9bc981
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101268- (2022)
Summary: Cellular RNAs are modified by both physiological factors and exogenous agents, such as methyl methanesulfonate (MMS). However, techniques for analyzing how proteins may interact with these modified RNAs are limited. Here, we provide a protoc
Externí odkaz:
https://doaj.org/article/1ca00d9120ea4276b04023fb49afed23
Autor:
Chih-Wei Chen, Ning Tsao, Lin-Yi Huang, Yun Yen, Xiyong Liu, Christine Lehman, Yuh-Hwa Wang, Mei-Chun Tseng, Yu-Ju Chen, Yi-Chi Ho, Chian-Feng Chen, Zee-Fen Chang
Publikováno v:
Cell Reports, Vol 16, Iss 5, Pp 1287-1299 (2016)
The appropriate supply of dNTPs is critical for cell growth and genome integrity. Here, we investigated the interrelationship between dUTP pyrophosphatase (dUTPase) and ribonucleotide reductase (RNR) in the regulation of genome stability. Our results
Externí odkaz:
https://doaj.org/article/7bcdea62638c4b54824ecf8f3ee19933
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 5048 (2020)
NME3 is a member of the nucleoside diphosphate kinase (NDPK) family that binds to the mitochondrial outer membrane to stimulate mitochondrial fusion. In this study, we showed that NME3 knockdown delayed DNA repair without reducing the cellular levels
Externí odkaz:
https://doaj.org/article/3be6ea91907c4e81841f0c9f4dfe1b8e
103
Cellular supply of deoxynucleoside triphosphates (dNTPs) is crucial for DNA replication and repair. Ribonucleotide reducatse (RNR) is a rate-limiting enzyme for dNTP synthesis required for DNA repair, by reduction of four ribonucleoside diph
Cellular supply of deoxynucleoside triphosphates (dNTPs) is crucial for DNA replication and repair. Ribonucleotide reducatse (RNR) is a rate-limiting enzyme for dNTP synthesis required for DNA repair, by reduction of four ribonucleoside diph
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/04750490829043069513
Autor:
Chieh-Ching Yen, Che-Fang Ho, Chia-Chien Wu, Yu-Ning Tsao, Chung-Hsien Chaou, Shou-Yen Chen, Chip-Jin Ng, Heng Yeh
Publikováno v:
Medicina, Vol 58, Iss 2, p 177 (2022)
Background and Objectives: The purpose of the present study was to elucidate the in-hospital and long-term outcomes of patients with head and neck cancer (HNC) bleeding and to analyze the risk factors for mortality. Materials and Methods: We included
Externí odkaz:
https://doaj.org/article/15e42b0ccfd647c184e0bfd7fec20746
Autor:
Nicolas Reynoird, Nima Mosammaparast, Pawel K. Mazur, Pierre Hainaut, Michiel Vermeulen, Yohann Couté, Pascal W.T.C. Jansen, Marianne Tardif, Rebecca Rodell, Jessica Vayr, Ana Morales Benitez, Florent Chuffart, Alexandre G. Casanova, Joshua R. Brickner, Ning Tsao, Tanveer Ahmad, Clement Oyeniran, Gael S. Roth, Simone Hausmann, Valentina Lukinović
Supplementary Table from SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032a5df391d5f4fa05c5afc7f2e1db25
https://doi.org/10.1158/2159-8290.22541404.v1
https://doi.org/10.1158/2159-8290.22541404.v1
Autor:
Nicolas Reynoird, Nima Mosammaparast, Pawel K. Mazur, Pierre Hainaut, Michiel Vermeulen, Yohann Couté, Pascal W.T.C. Jansen, Marianne Tardif, Rebecca Rodell, Jessica Vayr, Ana Morales Benitez, Florent Chuffart, Alexandre G. Casanova, Joshua R. Brickner, Ning Tsao, Tanveer Ahmad, Clement Oyeniran, Gael S. Roth, Simone Hausmann, Valentina Lukinović
Small cell lung cancer (SCLC) is the most fatal form of lung cancer, with dismal survival, limited therapeutic options, and rapid development of chemoresistance. We identified the lysine methyltransferase SMYD3 as a major regulator of SCLC sensitivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7aff3a4b13eb09415758e2513af039
https://doi.org/10.1158/2159-8290.c.6549634.v1
https://doi.org/10.1158/2159-8290.c.6549634.v1
Autor:
Nicolas Reynoird, Nima Mosammaparast, Pawel K. Mazur, Pierre Hainaut, Michiel Vermeulen, Yohann Couté, Pascal W.T.C. Jansen, Marianne Tardif, Rebecca Rodell, Jessica Vayr, Ana Morales Benitez, Florent Chuffart, Alexandre G. Casanova, Joshua R. Brickner, Ning Tsao, Tanveer Ahmad, Clement Oyeniran, Gael S. Roth, Simone Hausmann, Valentina Lukinović
Supplementary Data from SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01500e10207400a070376439f471923d
https://doi.org/10.1158/2159-8290.22541428.v1
https://doi.org/10.1158/2159-8290.22541428.v1