Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Ning Sheng Cai"'
Publikováno v:
BioTechniques, Vol 65, Iss 1, Pp 9-14 (2018)
Protein complementation assays (PCA) are used as pharmacological tools, enabling a wide array of applications, ranging from studies of protein–protein interactions to second messenger effects. Methods to detect activities of G protein-coupled recep
Externí odkaz:
https://doaj.org/article/99b352e874484e2592c0a5f9724a88c4
Autor:
Xi Wang, Alexandre Westermann, Yi Xiang Shi, Ning Sheng Cai, Mathilde Rieu, Jean-Paul Viricelle, Philippe Vernoux
Publikováno v:
Catalysts, Vol 7, Iss 2, p 61 (2017)
This study reports the electrochemical properties for NOx reduction of a ceria-based mixed ionic electronic conducting porous electrode promoted by Pt nanoparticles, as efficient catalyst for NO oxidation, and BaO, as sorbent to store NOx. This catal
Externí odkaz:
https://doaj.org/article/7cad84ca91ce4658ac8cf5643e632c60
Autor:
Jean Lud Cadet, Michael T McCoy, Ning Sheng Cai, Irina N Krasnova, Bruce Ladenheim, Genevieve Beauvais, Natascha Wilson, William Wood, Kevin G Becker, Amber B Hodges
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7812 (2009)
Methamphetamine (METH) is an illicit drug which is neurotoxic to the mammalian brain. Numerous studies have revealed significant decreases in dopamine and serotonin levels in the brains of animals exposed to moderate-to-large METH doses given within
Externí odkaz:
https://doaj.org/article/717031b9054640ed8ba66bda7e95c587
Autor:
Attila Köfalvi, Estefanía Moreno, Arnau Cordomí, Ning-Sheng Cai, Victor Fernández-Dueñas, Samira G. Ferreira, Ramón Guixà-González, Marta Sánchez-Soto, Hideaki Yano, Verònica Casadó-Anguera, Rodrigo A. Cunha, Ana Maria Sebastião, Francisco Ciruela, Leonardo Pardo, Vicent Casadó, Sergi Ferré
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-21 (2020)
Abstract Background It has been hypothesized that heteromers of adenosine A2A receptors (A2AR) and cannabinoid CB1 receptors (CB1R) localized in glutamatergic nerve terminals mediate the integration of adenosine and endocannabinoid signaling involved
Externí odkaz:
https://doaj.org/article/7b04e035274446de8e3bed6703c6c493
Autor:
Gemma Navarro, Arnau Cordomí, Verónica Casadó-Anguera, Estefanía Moreno, Ning-Sheng Cai, Antoni Cortés, Enric I. Canela, Carmen W. Dessauer, Vicent Casadó, Leonardo Pardo, Carme Lluís, Sergi Ferré
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
It is unclear whether GPCRs, G proteins and adenylyl cyclase (AC) associate through random collisions or defined pre-coupling mechanisms. Using a peptide-based approach, the authors show that heteromers of adenosine A2A and dopamine D2 receptors form
Externí odkaz:
https://doaj.org/article/ddb2e76a96254f8299931ae5586deefc
Autor:
Hideaki Yano, Ning-Sheng Cai, Min Xu, Ravi Kumar Verma, William Rea, Alexander F. Hoffman, Lei Shi, Jonathan A. Javitch, Antonello Bonci, Sergi Ferré
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
D1-like dopamine receptors are coupled to Golf proteins in the dorsal striatum but Gs in cortical and other areas. Here, the authors demonstrate selective agonism of Gs-coupled versus Golf-coupled D1 receptors.
Externí odkaz:
https://doaj.org/article/6269903e50c3459fb1f298160b9253b7
Autor:
Sergi Ferré, Annabelle M. Belcher, Jordi Bonaventura, César Quiroz, Marta Sánchez-Soto, Verònica Casadó-Anguera, Ning-Sheng Cai, Estefanía Moreno, Comfort A. Boateng, Thomas M. Keck, Benjamín Florán, Christopher J. Earley, Francisco Ciruela, Vicent Casadó, Marcelo Rubinstein, Nora D. Volkow
Publikováno v:
Frontiers in Endocrinology. 13
The functional and pharmacological significance of the dopamine D4 receptor (D4R) has remained the least well understood of all the dopamine receptor subtypes. Even more enigmatic has been the role of the very prevalent human DRD4 gene polymorphisms
Autor:
Estefanía Moreno, Nil Casajuana-Martin, Michael Coyle, Baruc Campos Campos, Ewa Galaj, Claudia Llinas del Torrent, Arta Seyedian, William Rea, Ning-Sheng Cai, Alessandro Bonifazi, Benjamín Florán, Zheng-Xiong Xi, Xavier Guitart, Vicent Casadó, Amy H. Newman, Christopher Bishop, Leonardo Pardo, Sergi Ferré
Publikováno v:
Pharmacological research. 185
A main rationale for the role of G protein-coupled receptor (GPCR) heteromers as targets for drug development is the putative ability of selective ligands for specific GPCRs to change their pharmacological properties upon GPCR heteromerization. The p
Autor:
Paulo A, De Oliveira, Estefanía, Moreno, Nil, Casajuana-Martin, Verònica, Casadó-Anguera, Ning-Sheng, Cai, Gisela Andrea, Camacho-Hernandez, Hu, Zhu, Alessandro, Bonifazi, Matthew D, Hall, David, Weinshenker, Amy Hauck, Newman, Diomedes E, Logothetis, Vicent, Casadó, Leigh D, Plant, Leonardo, Pardo, Sergi, Ferré
Publikováno v:
Pharmacological research. 182
Recent studies have proposed that heteromers of µ-opioid receptors (MORs) and galanin Gal
Autor:
Estefanía Moreno, Ning-Sheng Cai, Marta Sánchez-Soto, Vicent Casadó, Verònica Casadó-Anguera, Sergi Ferré, Hideaki Yano
Publikováno v:
Molecular Neurobiology. 56:4778-4785
The two most common polymorphisms of the human DRD4 gene encode a dopamine D4 receptor (D4R) with four or seven repeats of a proline-rich sequence of 16 amino acids (D4.4R or D4.7R). Although the seven-repeat polymorphism has been repeatedly associat