Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs

Autor: Rüdiger Moltrecht, K. Bianka Seres, Jennifer R. Gruhn, Heike Eckel, Eva Hoffmann, Martyn Blayney, Kay Elder, Ann-Sophie Frombach, Eirini Bellou, Ninadini Sharma, Melina Schuh, Agata P. Zielinska

Publikováno v: Zielinska, A P, Bellou, E, Sharma, N, Frombach, A S, Seres, K B, Gruhn, J R, Blayney, M, Eckel, H, Moltrecht, R, Elder, K, Hoffmann, E R & Schuh, M 2019, ' Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs ', Current Biology, vol. 29, no. 22, pp. 3749-3765.e7 . https://doi.org/10.1016/j.cub.2019.09.006
Current Biology

Summary Chromosome segregation errors during female meiosis are a leading cause of pregnancy loss and human infertility. The segregation of chromosomes is driven by interactions between spindle microtubules and kinetochores. Kinetochores in mammalian

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https://curis.ku.dk/portal/da/publications/meiotic-kinetochores-fragment-into-multiple-lobes-upon-cohesin-loss-in-aging-eggs(db65c38b-cfb3-4c93-933b-bcee29fc0e69).html