Altered Expression of Multiple Genes Involved in Retinoic Acid Biosynthesis in Human Colorectal Cancer

Autor: Vladimir S. Prasolov, Ekaterina S. Kropotova, Vera I. Dybovaya, Olga Zinovieva, T. D. Mashkova, Nina Yu. Oparina, Alisa F. Zyryanova, Sergey F. Beresten

Publikováno v: Pathology & Oncology Research. 20:707-717

All-trans-retinoic acid (atRA), the oxidized form of vitamin A (retinol), regulates a wide variety of biological processes, such as cell proliferation and differentiation. Multiple alcohol, retinol and retinaldehyde dehydrogenases (ADHs, RDHs, RALDHs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8ec185e7f775be1d3957fdbb5c3391
https://doi.org/10.1007/s12253-014-9751-4

Impact of recombination on polymorphism of genes encoding Kunitz-type protease inhibitors in the genus Solanum

Autor: Anastasia A. Krinitsina, Marina A. Guseva, Angelo Santino, A. B. Shevelev, Anna V. Kudryavtseva, Alexey A. Dmitriev, Nina Yu. Oparina, Palmiro Poltronieri, Anna S. Speranskaya, Maxim S. Belenikin

Publikováno v: Biochimie
94 (2012): 1687–1696. doi:10.1016/j.biochi.2012.03.010
info:cnr-pdr/source/autori:Speranskaya A.S; Krinitsina A.A; Kudryavtseva A.V; Poltronieri P; Santino A; Oparina N.Y; Dmitriev A.A; Belenikin M.S; Guseva M.A; Shevelev A.B/titolo:Impact of recombination on polymorphism of genes encoding Kunitz-type protease inhibitors in the genus Solanum/doi:10.1016%2Fj.biochi.2012.03.010/rivista:Biochimie (Print)/anno:2012/pagina_da:1687/pagina_a:1696/intervallo_pagine:1687–1696/volume:94

Background The group of Kunitz-type protease inhibitors (KPI) from potato is encoded by a polymorphic family of multiple allelic and non-allelic genes. The previous explanations of the KPI variability were based on the hypothesis of random mutagenesi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a41f76d7437f49b57f2e916a314f34
https://doi.org/10.1016/j.biochi.2012.03.010

Non-random DNA fragmentation in next-generation sequencing

Autor: Maria Poptsova, Dmitry Yu. Nechipurenko, S. L. Grokhovsky, Il'icheva Ia, Mingian V. Khodikov, Yury D. Nechipurenko, R. V. Polozov, Nina Yu. Oparina, L. A. Panchenko

Publikováno v: Scientific Reports

Next Generation Sequencing (NGS) technology is based on cutting DNA into small fragments, and their massive parallel sequencing. The multiple overlapping segments termed “reads” are assembled into a contiguous sequence. To reduce sequencing error

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55e6b247613523d3288152b5b59b767
https://pubmed.ncbi.nlm.nih.gov/24681819

Prediction of amino acid residues participated in substrate recognition by cytochrome P450 subfamilies with broad substrate specificity

Autor: Maria S, Zharkova, Boris N, Sobolev, Nina, Yu Oparina, Alexander V, Veselovsky, Alexander I, Archakov

Publikováno v: Journal of molecular recognition : JMR. 26(2)

Cytochromes P450 comprise a large superfamily and several of their isoforms play a crucial role in metabolism of xenobiotics, including drugs. Although these enzymes demonstrate broad and cross-substrate specificity, different cytochrome P450 subfami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b116991bad56ece6423888ba0f9f8b07
https://pubmed.ncbi.nlm.nih.gov/23334916

Mutations in the highly conserved GGQ motif of class 1 polypeptide release factors abolish ability of human eRF1 to trigger peptidyl-tRNA hydrolysis

Autor: Oleg I. Serpinsky, Blinov Vm, Sergey I. Tatkov, Nina Yu. Oparina, Ruslan Yu. Tsivkovskii, Ludmila Frolova, Lev L. Kisselev, Galina F. Sivolobova

Publikováno v: RNA (New York, N.Y.). 5(8)

Although the primary structures of class 1 polypeptide release factors (RF1 and RF2 in prokaryotes, eRF1 in eukaryotes) are known, the molecular basis by which they function in translational termination remains obscure. Because all class 1 RFs promot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b6c617dffdb2180df0805076cc7bff
https://pubmed.ncbi.nlm.nih.gov/10445876