Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nina Y. Chiu"'
Autor:
Bethany A. Adair, Andrea J. Korecki, Diana Djaksigulova, Pamela K. Wagner, Nina Y. Chiu, Siu Ling Lam, Tess C. Lengyell, Blair R. Leavitt, Elizabeth M. Simpson
Publikováno v:
Ophthalmology and Therapy, Vol 12, Iss 4, Pp 2049-2068 (2023)
Abstract Introduction Aniridia is a rare congenital vision-loss disease caused by heterozygous variants in the PAX6 gene. There is no vision-saving therapy, but one exciting approach is to use CRISPR/Cas9 to permanently correct the causal genomic var
Externí odkaz:
https://doaj.org/article/236a9d7004ac47589a17158051a80833
Autor:
Seyedeh Zeinab Mirjalili Mohanna, Jack W. Hickmott, Siu Ling Lam, Nina Y. Chiu, Tess C. Lengyell, Beatrice M. Tam, Orson L. Moritz, Elizabeth M. Simpson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 478-490 (2020)
Aniridia is a rare eye disorder, which is caused by mutations in the paired box 6 (PAX6) gene and results in vision loss due to the lack of a long-term vision-saving therapy. One potential approach to treating aniridia is targeted CRISPR-based genome
Externí odkaz:
https://doaj.org/article/72def171bf954da9a10a19c51103507a