Multiscale statistical physics of the pan-viral interactome unravels the systemic nature of SARS-CoV-2 infections

Autor: Arsham Ghavasieh, Sebastiano Bontorin, Oriol Artime, Nina Verstraete, Manlio De Domenico

Publikováno v: Communications Physics, Vol 4, Iss 1, Pp 1-13 (2021)

Characterizing the interactions between viral and human proteins is key to understand the function and structure of viruses such as SARS-CoV-2 and for informing drug design and repurposing strategies. Here, the authors use statistical physics techniq

Externí odkaz: https://doaj.org/article/6c3ec879512740d28f17babc13acf0d4

The impact of ICT characteristics on students’ learning outcomes during COVID-19 lockdown period: the crucial role of techno eustress perception

Autor: Anuragini Shirish, Nina Verstraete, Olfa Chourabi Tantan

Publikováno v: Human Systems Management
Human Systems Management, 2023, 42 (2), pp.149-162. ⟨10.3233/HSM-220059⟩

HCERES C; International audience; BACKGROUND: The COVID-19 crisis led to an unprecedented acceleration of digital learning. It pushed many institutions to abruptly switch to fully online learning modes from face-to-face learning. Prior studies show t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25aa26ded8889d0b4308a66738a8125f
https://hal.science/hal-03752991

An Agent-Based Model of Monocyte Differentiation into Tumour-Associated Macrophages in Chronic Lymphocytic Leukemia

Autor: Nina Verstraete, Malvina Marku, Marcin Domagala, Hélène Arduin, Julie Bordenave, Jean-Jacques Fournié, Loïc Ysebaert, Mary Poupot, Vera Pancaldi

Monocyte-derived macrophages help maintain tissue homeostasis and defend the organism against pathogens. In tumors, recent studies have uncovered complex macrophage populations, including tumor-associated macrophages, which support tumorigenesis thro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31cb61eb83ac4ddfcc4d78533da1151e
https://doi.org/10.1101/2021.12.17.473137

Insights on TAM Formation from a Boolean Model of Macrophage Polarization Based on In Vitro Studies

Autor: Mary Poupot, Vera Pancaldi, Nina Verstraete, Jean-Jacques Fournié, Miguel Madrid-Mencía, Flavien Raynal, Marcin Domagala, Malvina Marku, Loic Ysebaert

Publikováno v: Cancers, Vol 12, Iss 3664, p 3664 (2020)
Cancers
Volume 12
Issue 12
Cancers, MDPI, 2020, 12 (12), pp.3664. ⟨10.3390/cancers12123664⟩
Cancers, 2020, 12 (12), pp.3664. ⟨10.3390/cancers12123664⟩

Simple Summary The recent success of immunotherapy treatments against cancer relies on helping our own body’s defenses in the fight against tumours, namely reinvigorating the cancer killing action of T cells. Unfortunately, in a large proportion of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bc67931c7d9bc5c1595f5081c47407
https://www.mdpi.com/2072-6694/12/12/3664

CovMulNet19, Integrating Proteins, Diseases, Drugs, and Symptoms: A Network Medicine Approach to COVID-19

Autor: Manlio De Domenico, Giulia Bertagnolli, Giuseppe Jurman, Arsham Ghavasieh, Vera Pancaldi, Nina Verstraete

Publikováno v: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Network and Systems Medicine

Introduction: We introduce in this study CovMulNet19, a comprehensive COVID-19 network containing all available known interactions involving SARS-CoV-2 proteins, interacting-human proteins, diseases and symptoms that are related to these human protei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebff83e14e9242646c4ccc10daea9245
http://hdl.handle.net/2117/346644