Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nina V. Capillé"'
Autor:
Stephan N. M. C. G. Oliveira, Francisco F. Bezerra, Adriana A. Piquet, Rodrigo A. Sales, Gabrielly C. T. Valle, Nina V. Capillé, Ana M. F. Tovar, Paulo A. S. Mourão
Publikováno v:
ACS Omega, Vol 9, Iss 21, Pp 23111-23120 (2024)
Externí odkaz:
https://doaj.org/article/e4fd4d7a81ba491fb4f2b2a7cf23942f
Autor:
Stephan N.M.C.G. Oliveira, Ana M.F. Tovar, Francisco F. Bezerra, Adriana A. Piquet, Nina V. Capillé, Paloma S. Santos, Eduardo Vilanova, Paulo A.S. Mourão
Publikováno v:
TH Open, Vol 06, Iss 04, Pp e309-e322 (2022)
Heparin has already been found in a variety of animal tissues but only few of them became effective sources for production of pharmaceutical preparations. Here, we correlate physical-chemical features and anticoagulant activities of structurally simi
Externí odkaz:
https://doaj.org/article/2e7a794c0a5b4812b45bf16ff6289cae
Autor:
Roberto P. Santos, Ana M.F. Tovar, Marcos R. Oliveira, Adriana A. Piquet, Nina V. Capillé, Stephan N.M.C.G. Oliveira, Ana H. Correia, José N. Farias, Eduardo Vilanova, Paulo A.S. Mourão
Publikováno v:
TH Open, Vol 06, Iss 02, Pp e114-e123 (2022)
Heparin is a centennial anticoagulant drug broadly employed for treatment and prophylaxis of thromboembolic conditions. Although unfractionated heparin (UFH) has already been shown to have remarkable pharmacological potential for treating a variety o
Externí odkaz:
https://doaj.org/article/f43f4cd91e9b4cfa8e41de4419042cd5
Autor:
Francisco Felipe Bezerra, Stephan N.M.C.G. Oliveira, Rodrigo A. Sales, Adriana A. Piquet, Nina V. Capillé, Eduardo Vilanova, Ana M.F. Tovar, Paulo A.S. Mourão
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1115 (2023)
Pharmaceutical heparins from different manufacturers may present heterogeneities due to particular extraction and purification procedures or even variations in the raw material manipulation. Heparins obtained from different tissues also differ in the
Externí odkaz:
https://doaj.org/article/5162564403cd4d2d9c320a111ed9e50d
Autor:
Eduardo Vilanova, Bruno C. Vairo, Stephan-Nicollas M. C. G. Oliveira, Bianca F. Glauser, Nina V. Capillé, Gustavo R. C. Santos, Ana M. F. Tovar, Mariana S. Pereira, Paulo A. S. Mourão
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Most of the unfractionated heparin (UFH) consumed worldwide is manufactured using porcine mucosa as raw material (HPI); however, some countries also employ products sourced from bovine mucosa (HBI) as interchangeable versions of the gold standard HPI
Externí odkaz:
https://doaj.org/article/0cead5ede1bf432d97bf77cc50437d39
Autor:
Paulo A.G. Soares, Nina V. Capillé, Ana M. F. Tovar, Stephan-Nicollas M. C. G. Oliveira, Ana P. Valente, Eduardo Vilanova, Kátia A Ribeiro, Mariana S. Pereira, Paulo A.S. Mourão
Publikováno v:
Glycobiology. 28:565-579
Fucosylated chondroitin sulfates (FCSs) and sulfated fucans (SFs) are conspicuous components of the body wall of sea cucumbers (Holothuroidea). FCSs are composed of a central core of chondroitin sulfate (CS) decorated with branches of mono- or both m
Autor:
Eduardo Vilanova, Bianca F. Glauser, Mariana S. Pereira, Adriana A. Piquet, Bruno C. Vairo, Kayene Vitória de A Micheli, Paulo A.S. Mourão, Paloma S. Santana, Stephan-Nicollas M. C. G. Oliveira, Ana M. F. Tovar, Gustavo R.C. Santos, Nina V. Capillé
Publikováno v:
Thrombosis and haemostasis. 119(4)
Unfractionated heparin (UFH) and their low-molecular-weight derivatives are sourced almost exclusively from porcine mucosa (HPI); however, a worldwide introduction of UFH from bovine mucosa (HBI) has been recommended to reinforce the currently unstea
Autor:
Bruno C. Vairo, Ana M. F. Tovar, Bianca F. Glauser, Paulo A.S. Mourão, Eduardo Vilanova, Nina V. Capillé, Mariana S. Pereira, Gustavo R.C. Santos, Stephan-Nicollas M. C. G. Oliveira
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Frontiers in Medicine
Frontiers in Medicine
Most of the unfractionated heparin (UFH) consumed worldwide is manufactured using porcine mucosa as raw material (HPI); however, some countries also employ products sourced from bovine mucosa (HBI) as interchangeable versions of the gold standard HPI
Autor:
Mariana S. Pereira, Stephan-Nicollas M. C. G. Oliveira, Nina V. Capillé, Vitor H. Pomin, Paulo A.S. Mourão, Gustavo R.C. Santos, Bianca F. Glauser, Ismael Nilo Lino de Queiroz
Publikováno v:
Thrombosis and Haemostasis. 113:53-65
SummaryBiosimilar enoxaparins have been available for clinical use in Brazil since 2009. Although their use has reduced costs of treatment expenses, their implementation still raises some concerns about efficiency, safety, regularity and reproducibil
Autor:
Ana M. F. Tovar, Paulo A.S. Mourão, Nina V. Capillé, Eduardo Vilanova, Bianca F. Glauser, Adriana A. Piquet, Gustavo R.C. Santos, Mariana S. Pereira
Publikováno v:
Scientific Reports
Heparins extracted from different animal sources have been conventionally considered effective anticoagulant and antithrombotic agents despite of their pharmacological dissimilarities. We performed herein a systematic analysis on the physicochemical