Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nina Sopel"'
Publikováno v:
Cells, Vol 11, Iss 1, p 149 (2022)
Nephronectin (NPNT) is an extracellular matrix protein in the glomerular basement membrane that is produced by podocytes and is important for the integrity of the glomerular filtration barrier. Upregulated transforming growth factor β (TGF-β) and a
Externí odkaz:
https://doaj.org/article/b0226851d81240faa5f5e7e7760606c5
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Asthma bronchiale is a disease of the airways with increasing incidence, that often begins during infancy. So far, therapeutic options are mainly symptomatic and thus there is an increasing need for better treatment and/or prevention strategies. Huma
Externí odkaz:
https://doaj.org/article/ddba0be09c0347ecb276428a11f9398d
Autor:
Raluca Ursu, Nina Sopel, Alexandra Ohs, Ramesh Tati, Lisa Buvall, Jenny Nyström, Mario Schiffer, Janina Müller-Deile
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 15070
Deciphering the pathophysiological mechanisms of primary podocytopathies that can lead to end-stage renal disease and increased mortality is an unmet need. Studying how microRNAs (miRs) interfere with various signaling pathways enables identification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c760b16d49f68a40da5b3e8faefc71d
Autor:
Janina Müller-Deile, Victoria Rose, Jan Hegermann, Christoph Daniel, Kerstin Amann, Marwin Gröner, Mario Schiffer, Nina Sopel, Alexandra Ohs, Christoph Wrede, Gunther Zahner
Publikováno v:
J Am Soc Nephrol
Background Autoantibodies binding to podocyte antigens cause idiopathic membranous glomerulonephritis (iMGN). However, it remains elusive how autoantibodies reach the subepithelial space because the glomerular filtration barrier (GFB) is size selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c808ba1e58f1854cc5584bc3252156
https://doi.org/10.1681/asn.2020121699
https://doi.org/10.1681/asn.2020121699
Autor:
Victoria Rose, Nina Sopel, Alexandra Ohs, Christina Warnecke, Mario Schiffer, Janina Müller-Deile
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Genetic focal segmental glomerulosclerosis (FSGS) is related to irreversible damage of the filtration barrier and podocyte effacement. More than 40 genes with mutations, involved in slit diaphragm formation, actin cytoskeleton syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1729a2859aee3d9f7841c8341fe9f016
https://doi.org/10.1093/ndt/gfac104.002
https://doi.org/10.1093/ndt/gfac104.002
Autor:
Janina Müller-Deile, Nina Sopel
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9152, p 9152 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Epigenetic modifications are able to alter gene expression and include DNA methylation, different histone variants, and post-transcriptional modifications (PTMs), such as acetylation or phosphorylation, and through short/long RNAs, respectively. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6053b0e2d9caa3a30bcbc5062f7e64a
https://www.mdpi.com/1422-0067/22/17/9152
https://www.mdpi.com/1422-0067/22/17/9152
Autor:
Johannes Kornhuber, Sonja Koch, Susetta Finotto, Nina Sopel, Julia Kölle, Cosima Rhein, Martin Reichel, Sonja Dumendiak
Publikováno v:
Immunology. 156:373-383
Acid sphingomyelinase (ASM) is one of the enzymes that catalyzes the breakdown of sphingomyelin to ceramide and phosphorylcholine. In this study, we aimed at elucidating the role of ASM in allergic asthma. We used an ovalbumin‐induced murine model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c42b1970978dd83c3520a4221454e3
https://doi.org/10.1111/imm.13035
https://doi.org/10.1111/imm.13035
Autor:
Victoria Rose, Janina Müller-Deile, Nina Sopel, Alexandra Ohs, Christina Warnecke, Mario Schiffer
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims The smallest filtration unit of the kidney, the glomerulus, is composed of capillaries formed by glomerular endothelial cells (GEC), glomerular basement membrane and podocytes. Furthermore, glomerular mesangial cells (GMC) between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28258e806f52e18385e4bfd4644d9297
https://doi.org/10.1093/ndt/gfab079.001
https://doi.org/10.1093/ndt/gfab079.001
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims The glomerular basement membrane (GBM), podocytes and glomerular endothelial cells (GEC) are composing the glomerular filtration barrier (GFB) within the glomerulus. Both podocytes and GEC are essential components for the synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::882c0110d9ec04b0774ba16320645241
https://doi.org/10.1093/ndt/gfab079.007
https://doi.org/10.1093/ndt/gfab079.007
Autor:
Alexandra Ohs, Groener Marwin, Janina Müller-Deile, Ahmed Kotb, Mario Schiffer, Christoph Daniel, Kerstin Amann, Nina Sopel
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims Autoantibodies binding to podocyte antigens cause idiopathic membranous glomerulonephritis (iMGN). However, it remains elusive how autoantibodies reach the subepithelial space because the glomerular filtration barrier is normally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a1b63becef7c5415fb6d0592cf50951
https://doi.org/10.1093/ndt/gfab120.001
https://doi.org/10.1093/ndt/gfab120.001