Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nina Schmolka"'
Autor:
Nina Schmolka, Ino D. Karemaker, Richard Cardoso da Silva, Davide C. Recchia, Vincent Spegg, Jahnavi Bhaskaran, Michael Teske, Nathalie P. de Wagenaar, Matthias Altmeyer, Tuncay Baubec
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The Nucleosome Remodeling and Deacetylation (NuRD) complex is a crucial regulator of cellular differentiation. Two members of the Methyl-CpG-binding domain (MBD) protein family, MBD2 and MBD3, are known to be integral, but mutually exclusive
Externí odkaz:
https://doaj.org/article/66c7c83fa81b49c2b95f6c7642a549d4
Autor:
Francisco Caiado, Diogo Maia-Silva, Carolina Jardim, Nina Schmolka, Tânia Carvalho, Cláudia Reforço, Rita Faria, Branka Kolundzija, André E. Simões, Tuncay Baubec, Christopher R. Vakoc, Maria Gomes da Silva, Markus G. Manz, Ton N. Schumacher, Håkan Norell, Bruno Silva-Santos
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The development of post-chemotherapy resistance is a significant issue in the management of AML. Here, Caiado et al. suggest that the issue might be circumvented via upfront combination with hypomethylating agents that shape the clonal dynamics and t
Externí odkaz:
https://doaj.org/article/b7dfc820cd8046b7b9099018be4d92e6
Autor:
Francisco Caiado, Diogo Maia-Silva, Carolina Jardim, Nina Schmolka, Tânia Carvalho, Cláudia Reforço, Rita Faria, Branka Kolundzija, André E. Simões, Tuncay Baubec, Christopher R. Vakoc, Maria Gomes da Silva, Markus G. Manz, Ton N. Schumacher, Håkan Norell, Bruno Silva-Santos
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/b8f06182e119402593d473bfdd9813b5
Autor:
Nina Schmolka, Maria Gomes da Silva, Tânia Carvalho, Carolina Jardim, Håkan Norell, Bruno Silva-Santos, Francisco Caiado, Ton N. Schumacher, Branka Kolundzija, Cláudia Reforço, Rita Faria, Diogo Maia-Silva, Tuncay Baubec, Christopher R. Vakoc, André E. Simões, Markus G. Manz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications
Chemotherapy-resistant cancer recurrence is a major cause of mortality. In acute myeloid leukemia (AML), chemorefractory relapses result from the complex interplay between altered genetic, epigenetic and transcriptional states in leukemic cells. Here
Autor:
Annika L. Gable, Stefan Butz, Philipp Voigt, Nina Schmolka, Rodrigo Villaseñor, Christian von Mering, Ruedi Aebersold, Thomas W. Sheahan, Joël Wirz, Ramon Pfaendler, Tuncay Baubec, Sara Giuliani, Christina Ambrosi, Elana Bryan, Christian Feller, Massimiliano Manzo
Publikováno v:
Villaseñor, R, Pfaendler, R, Ambrosi, C, Butz, S, Giuliani, S, Bryan, E, Sheahan, T W, Gable, A L, Schmolka, N, Manzo, M, Wirz, J, Feller, C, von Mering, C, Aebersold, R, Voigt, P & Baubec, T 2020, ' ChromID identifies the protein interactome at chromatin marks ', Nature Biotechnology, vol. 38, no. 6, pp. 728-736 . https://doi.org/10.1038/s41587-020-0434-2
Nature biotechnology
Nature Biotechnology
Nature Biotechnology, 38
Nature biotechnology
Nature Biotechnology
Nature Biotechnology, 38
Chromatin modifications regulate genome function by recruiting proteins to the genome. However, the protein composition at distinct chromatin modifications has yet to be fully characterized. In this study, we used natural protein domains as modular b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7afb8e36d8f4b906ff65aa5e23138387
https://www.pure.ed.ac.uk/ws/files/152360220/Villasenor_MS.pdf
https://www.pure.ed.ac.uk/ws/files/152360220/Villasenor_MS.pdf
Epigenetics refers to heritable phenotype changes that do not involve alterations in the DNA sequence. While DNA methylation and histone modifications represent the classical epigenetic mechanisms, RNA-based interference can also be integrated into t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49726e5eafb45c86e96a306ceec1aee6
https://doi.org/10.1016/b978-0-12-817964-2.00004-6
https://doi.org/10.1016/b978-0-12-817964-2.00004-6
Autor:
Esteban Ballestar, Jaydeep Bhat, Sajad Ahmad Bhat, Ziyi Chen, Shubhada Chiplunkar, Anjali deSouza, Avery DeVries, Humberto J. Ferreira, Sanjeev Galande, Ashok Giri, Anita Q. Gomes, Mariam Hakobyan, Mark Hartmann, Emily Hinkley, Dieter Kabelitz, Hemlata Kotkar, Jens Langstein, Jasmine Li, Tianlu Li, Wenhui Li, Daniel B. Lipka, Magdalena A. Machnicka, Ayush Madhok, Chinna Susan Philip, Rosario Michael Piro, Katarzyna Placek, F. Xiao-Feng Qin, Javier Rodríguez-Ubreva, Brendan E. Russ, Adem Saglam, Nina Schmolka, Maximilian Schönung, Jonas Schulte-Schrepping, Joachim L. Schultze, Bruno Silva-Santos, Sina Stäble, Shalini Kashipathi Sureshbabu, Aurore Touzart, Stephen J. Turner, Donata Vercelli, Justyna A. Wierzbinska, Bartek Wilczynski, Aiping Wu, Lianjun Zhang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47d63a38966a9dedc2263bdefad36c5a
https://doi.org/10.1016/b978-0-12-817964-2.09991-3
https://doi.org/10.1016/b978-0-12-817964-2.09991-3
Autor:
Natacha Gonçalves-Sousa, Julie C. Ribot, Pedro H. Papotto, Sofia Mensurado, Nina Schmolka, Bruno Silva-Santos, Andrea Iseppon, Brigitta Stockinger
Publikováno v:
EMBO Reports
EMBO reports
EMBO reports
Pro‐inflammatory interleukin (IL)‐17‐producing γδ (γδ17) T cells are thought to develop exclusively in the thymus during fetal/perinatal life, as adult bone marrow precursors fail to generate γδ17 T cells under homeostatic conditions. Her
Autor:
Ruedi Aebersold, Christina Ambrosi, Christian von Mering, Annika L. Gable, Nina Schmolka, Stefan Butz, Sara Giuliani, Philipp Voigt, Ramon Pfaendler, Tuncay Baubec, Christian Feller, Joël Wirz, Massimiliano Manzo, Elana Bryan, Thomas W. Sheahan, Rodrigo Villaseñor
Publikováno v:
Nature Biotechnology. 38:757-757
Autor:
Tuncay Baubec, Ton N. Schumacher, Cláudia Reforço, Diogo Maia-Silva, Christopher R. Vakoc, Håkan Norell, Carolina Jardim, Tânia Carvalho, Nina Schmolka, Maria Gomes da Silva, Francisco Caiado, André E. Simões, Markus G. Manz, Branka Kolundzija, Rita Faria, Bruno Silva-Santos
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Nature Communications
Nature Communications
An amendment to this paper has been published and can be accessed via a link at the top of the pape Chemotherapy-resistant cancer recurrence is a major cause of mortality. In acute myeloid leukemia (AML), chemorefractory relapses result from the comp