Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nina Schiller"'
Autor:
Vivekanandan Shanmuganathan, Nina Schiller, Anastasia Magoulopoulou, Jingdong Cheng, Katharina Braunger, Florian Cymer, Otto Berninghausen, Birgitta Beatrix, Kenji Kohno, Gunnar von Heijne, Roland Beckmann
Publikováno v:
eLife, Vol 8 (2019)
XBP1u, a central component of the unfolded protein response (UPR), is a mammalian protein containing a functionally critical translational arrest peptide (AP). Here, we present a 3 Å cryo-EM structure of the stalled human XBP1u AP. It forms a unique
Externí odkaz:
https://doaj.org/article/f441759e29854117a41889883f5b50a1
Autor:
Gunnar von Heijne, Anastasia Magoulopoulou, Jingdong Cheng, Katharina Braunger, Florian Cymer, Roland Beckmann, Vivekanandan Shanmuganathan, B. Beatrix, Otto Berninghausen, Kenji Kohno, Nina Schiller
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eb4c9e0a6638b000f4a1917ddd16d74
https://doi.org/10.7554/elife.46267.038
https://doi.org/10.7554/elife.46267.038
Autor:
Katharina Braunger, Nina Schiller, Florian Cymer, Otto Berninghausen, Gunnar von Heijne, B. Beatrix, Anastasia Magoulopoulou, Roland Beckmann, Jingdong Cheng, Kenji Kohno, Vivekanandan Shanmuganathan
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
XBP1u, a central component of the unfolded protein response (UPR), is a mammalian protein containing a functionally critical translational arrest peptide (AP). Here, we present a 3 Å cryo-EM structure of the stalled human XBP1u AP. It forms a unique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab39a9d8cff841aaaca37c37b72cb9ee
https://doi.org/10.1101/588681
https://doi.org/10.1101/588681
Autor:
Malin Cammenberg, Hourinaz Behesti, Nina Schiller, IngMarie Nilsson, Amanda Liljenström, Karl Enquist, Gunnar von Heijne, Åsa Tellgren-Roth, Mary E. Hatten, Patricia Lara, Zachi Horn
Publikováno v:
The Journal of biological chemistry. 294(12)
Astrotactin 1 (Astn1) and Astn2 are membrane proteins that function in glial-guided migration, receptor trafficking, and synaptic plasticity in the brain as well as in planar polarity pathways in the skin. Here we used glycosylation mapping and prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f81494479b4e6fb64934715af80103c
https://pubmed.ncbi.nlm.nih.gov/30696770
https://pubmed.ncbi.nlm.nih.gov/30696770
Autor:
Hourinaz Behesti, IngMarie Nilsson, Amanda Liljenström, Mary E. Hatten, Karl Enquist, Patricia Lara, Åsa Tellgren-Roth, Zachi Horn, Gunnar von Heijne, Malin Cammenberg, Nina Schiller
Astrotactins 1 (Astn1) and Astn2 are membrane proteins that function in glial-guided migration, receptor trafficking and synaptic plasticity in the brain, as well as in planar polarity pathways in skin. Here, we used glycosylation mapping and proteas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f887f2b3bfbc26b80eca09d7e27223
Autor:
Kei Nanatani, Masao Sakaguchi, Jong-Kook Lee, Eriko Mishima, Naomi Hoshi, Nina Schiller, Yoko Sato, Nobuyuki Uozumi, Gunnar von Heijne
Publikováno v:
Biochemical Journal. 473:4361-4372
Voltage-dependent K+ (KV) channels control K+ permeability in response to shifts in the membrane potential. Voltage sensing in KV channels is mediated by the positively charged transmembrane domain S4. The best-characterized KV channel, KvAP, lacks t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97238f80354525c669922f79a1610d18
https://doi.org/10.1042/bcj20160746
https://doi.org/10.1042/bcj20160746
Publikováno v:
Biochemistry. 55:5772-5779
Insertion of a nascent membrane protein segment by the translocon channel into the bilayer is naturally promoted by high segmental hydrophobicity, but its selection as a transmembrane (TM) segment is complicated by the diverse environments (aqueous v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0eef222239056e869340d8e8f57e07
https://doi.org/10.1021/acs.biochem.6b00650
https://doi.org/10.1021/acs.biochem.6b00650
Publikováno v:
Biochemistry
Biophysical hydrophobicity scales suggest that partitioning of a protein segment from an aqueous phase into a membrane is governed by its perceived segmental hydrophobicity but do not establish specifically (i) how the segment is identified in vivo f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b5acf18ce4dd57a11970069562fc16
https://doi.org/10.1021/bi5014886
https://doi.org/10.1021/bi5014886
Xbp1, a protein involved in the unfolded protein response, is a rare example of a mammalian protein that contains a well-defined translational arrest peptide (AP). In order to define the critical residues in the Xbp1u AP, and to search for variants w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0579427e1773912f7e311b3469647cbf
https://doi.org/10.1101/201913
https://doi.org/10.1101/201913
Publikováno v:
Nature Structural & Molecular Biology. 19:1018-1022
Membrane proteins destined for insertion into the inner membrane of bacteria or the endoplasmic reticulum membrane in eukaryotic cells are synthesized by ribosomes bound to the bacterial SecYEG or the homologous eukaryotic Sec61 translocon. During co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01204ac71828d5d6a428afad0b02e6b5
https://doi.org/10.1038/nsmb.2376
https://doi.org/10.1038/nsmb.2376