Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Nina R. Salama"'
Autor:
Michael Bauer, Zuzana Nascakova, Anca-Irina Mihai, Phil F. Cheng, Mitchell P. Levesque, Simon Lampart, Robert Hurwitz, Lennart Pfannkuch, Jana Dobrovolna, Melanie Jacobs, Sina Bartfeld, Anders Dohlman, Xiling Shen, Alevtina A. Gall, Nina R. Salama, Antonia Töpfer, Achim Weber, Thomas F. Meyer, Pavel Janscak, Anne Müller
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The bacterial pathogen Helicobacter pylori is known for its ability to induce DNA double-strand breaks in the genome of its target cells. Here, we show that H. pylori-induced DNA damage and replication stress occurs in S-phase cells as a result of R-
Externí odkaz:
https://doaj.org/article/776595ded02849959ccfec289f6e8902
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT Helicobacter pylori is a bacterial pathogen that colonizes the human stomach, causing inflammation which, in some cases, leads to gastric ulcers and cancer. The clinical outcome of infection depends on a complex interplay of bacterial, host
Externí odkaz:
https://doaj.org/article/f33afe0fb3034b60aed4967ef1b0445e
Publikováno v:
mBio, Vol 7, Iss 5 (2016)
ABSTRACT Gland colonization may be one crucial route for bacteria to maintain chronic gastrointestinal infection. We developed a quantitative gland isolation method to allow robust bacterial population analysis and applied it to the gastric pathobion
Externí odkaz:
https://doaj.org/article/367ac532772e4d7faa03cb36fa6b4867
Publikováno v:
eLife, Vol 11 (2022)
The helical shape of Helicobacter pylori cells promotes robust stomach colonization; however, how the helical shape of H. pylori cells is determined is unresolved. Previous work identified helical-cell-shape-promoting protein complexes containing a p
Externí odkaz:
https://doaj.org/article/675f46ae859541f2a29b45c047249cf4
Autor:
Laura K Jackson, Barney Potter, Sean Schneider, Matthew Fitzgibbon, Kris Blair, Hajirah Farah, Uma Krishna, Trevor Bedford, Richard M Peek, Nina R Salama
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1008686 (2020)
Helicobacter pylori chronically infects the stomach of approximately half of the world's population. Manifestation of clinical diseases associated with H. pylori infection, including cancer, is driven by strain properties and host responses; and as c
Externí odkaz:
https://doaj.org/article/6c8cacf6d65844cfac2b8e20d1c914e3
Autor:
Jennifer A Taylor, Benjamin P Bratton, Sophie R Sichel, Kris M Blair, Holly M Jacobs, Kristen E DeMeester, Erkin Kuru, Joe Gray, Jacob Biboy, Michael S VanNieuwenhze, Waldemar Vollmer, Catherine L Grimes, Joshua W Shaevitz, Nina R Salama
Publikováno v:
eLife, Vol 9 (2020)
Helical cell shape is necessary for efficient stomach colonization by Helicobacter pylori, but the molecular mechanisms for generating helical shape remain unclear. The helical centerline pitch and radius of wild-type H. pylori cells dictate surface
Externí odkaz:
https://doaj.org/article/64ae3d39e00f4a1e9ae52bd11d5b915f
Autor:
Valerie P. O’Brien, Yuqi Kang, Meera K. Shenoy, Greg Finak, William C. Young, Julien Dubrulle, Lisa Koch, Armando E. Rodriguez Martinez, Jazmine A. Snow, Jeffery Williams, Elizabeth Donato, Surinder K. Batra, Cecilia C.S. Yeung, Susan Bullman, Meghan A. Koch, Raphael Gottardo, Nina R. Salama
Mechanisms forHelicobacter pylori(Hp)-driven stomach cancer are not fully understood. In a transgenic mouse model of gastric preneoplasia, concomitantHpinfection and induction of constitutively active KRAS (Hp+KRAS+) alters metaplasia phenotypes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa1fc21591ef9fdaad8f1713d12a7cd4
https://doi.org/10.1101/2022.12.20.521287
https://doi.org/10.1101/2022.12.20.521287
Autor:
Samuel I Miller, Nina R Salama
Publikováno v:
PLoS Biology, Vol 16, Iss 1, p e2004935 (2018)
Gram-negative bacteria are surrounded by two membrane bilayers separated by a space termed the periplasm. The periplasm is a multipurpose compartment separate from the cytoplasm whose distinct reducing environment allows more efficient and diverse me
Externí odkaz:
https://doaj.org/article/257d8c56856f4749859beae73f8b74b3
Publikováno v:
eLife. 11
The helical shape of