Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nina Oesterheld"'
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 119:11-16
The size of airborne particles determines their deposition pattern within the lungs and therefore, the efficacy of inhalation therapy. The present study analyzed factors affecting liquid atomization performed by vibrating-membrane technology. First,
Autor:
Thomas Schmehl, Moritz Beck-Broichsitter, Werner Seeger, Nina Oesterheld, Marie-Christine Knuedeler
Publikováno v:
International Journal of Pharmaceutics. 459:23-29
Pulmonary application of drug-loaded polymeric nanosuspensions is achieved by vibrating-mesh nebulizers, which allow for an output of intact nanocarriers from the nebulizer reservoir. However, adequate aerosol droplet sizes are a prerequisite for an
Autor:
Nina Oesterheld, Thomas Schmehl, Marie-Christine Knuedeler, Moritz Beck-Broichsitter, Werner Seeger
Publikováno v:
International Journal of Pharmaceutics. 461:34-37
Aerosolization of aqueous formulations is of special interest for inhalative drug delivery, where an adequate nebulizer performance represents a prerequisite for improving pulmonary therapy. The present study investigated the interplay of output rate
Autor:
Katharina Stoisiek, Alexandra C. Dalla-Bona, Tobias Gessler, Thomas Schmehl, Werner Seeger, Moritz Beck-Broichsitter, Nina Oesterheld
Publikováno v:
The Journal of pharmacy and pharmacology. 67(10)
Objectives This study investigated the controlled drug release potential of formulations revealing temperature-induced sol–gel transition following administration to the respiratory tract. Methods Diverse sildenafil-containing aqueous poloxamer 407
Publikováno v:
Journal of pharmaceutical sciences. 103(8)
Nebulization of active pharmaceutical ingredient (API) solutions is a well-established means to achieve pulmonary drug deposition. The current study identified the impact of formulation variables on the aerosolization performance of the eFlow®rapid