Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nina Noskovičová"'
Autor:
Sungji Cho, Keith Dadson, Hye Kyoung Sung, Oyeronke Ayansola, Ali Mirzaesmaeili, Nina Noskovicova, Yimu Zhao, Krisco Cheung, Milica Radisic, Boris Hinz, Ali A. Abdul Sater, Henry H. Hsu, Gary D. Lopaschuk, Gary Sweeney
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 171, Iss , Pp 116119- (2024)
Aims: Adiponectin has been shown to mediate cardioprotective effects and levels are typically reduced in patients with cardiometabolic disease. Hence, there has been intense interest in developing adiponectin-based therapeutics. The aim of this trans
Externí odkaz:
https://doaj.org/article/2ec58176acaf4663a927590bfe30c708
Publikováno v:
Cells, Vol 10, Iss 7, p 1794 (2021)
Body implants and implantable medical devices have dramatically improved and prolonged the life of countless patients. However, our body repair mechanisms have evolved to isolate, reject, or destroy any object that is recognized as foreign to the org
Externí odkaz:
https://doaj.org/article/e1e25390b9be4d7b89c71799ecfb9644
Autor:
Maya Ezzo, Nuno M. Coelho, Stellar Boo, Sander van Putten, David W. Griggs, Boris Hinz, Christopher A. McCulloch, Nina Noskovičová, Ronen Schuster, Peter G. Ruminski, Anne Koehler
Publikováno v:
Nature Biomedical Engineering. 5:1437-1456
The fibrotic encapsulation of implants involves the mechanical activation of myofibroblasts and of pro-fibrotic transforming growth factor beta 1 (TGF-β1). Here, we show that both softening of the implant surfaces and inhibition of the activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005d92d382f815aae7f280c7eb3f9ade
https://doi.org/10.1038/s41551-021-00722-z
https://doi.org/10.1038/s41551-021-00722-z
Autor:
Adeline Raignault, Justin Grant, Keith Dadson, Jessie S. Jeon, Gary Sweeney, James Jonkman, Boris Hinz, Nina Noskovičová, Teresa Chu, Trevor D. McKee, Seunggyu Kim, Nanyoung Yoon, Thanh Q. Dang, Scott P. Kelly, Jeffrey D. Peterson, Eric Thorin
Publikováno v:
Am J Physiol Endocrinol Metab
Adiponectin, a highly abundant polypeptide hormone in plasma, plays an important role in the regulation of energy metabolism in a wide variety of tissues, as well as providing important beneficial effects in diabetes, inflammation, and cardiovascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7400d238f7cca440ba0b33e752253f26
https://doi.org/10.1152/ajpendo.00564.2018
https://doi.org/10.1152/ajpendo.00564.2018
Autor:
Nina Noskovičová, Dong Ok Son, Boris Hinz, Monika Lodyga, Ronen Schuster, Henna Karvonen, Pardis Pakshir, Amanda Goodwin
Publikováno v:
Journal of cell science. 133(13)
In 1971, Gabbiani and co-workers discovered and characterized the “modification of fibroblasts into cells which are capable of an active spasm” (contraction) in rat wound granulation tissue and, accordingly, named these cells ‘myofibroblasts’
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851bbaddc8ea5cba729c31617fa71a38
https://pubmed.ncbi.nlm.nih.gov/32651236
https://pubmed.ncbi.nlm.nih.gov/32651236
Autor:
Marion Frankenberger, Oliver Eickelberg, Michael Lindner, Mareike Lehmann, Nina Noskovičová, Rudolf Hatz, Katharina Heinzelmann, Jürgen Behr, Melanie Königshoff, Anne Hilgendorff, Michael Gerckens
Publikováno v:
Am. J. Physiol. Lung Cell Mol. Physiol. 315, L682-L696 (2018)
Fibroblasts play an important role in lung homeostasis and disease. In lung fibrosis, fibroblasts adopt a proliferative and migratory phenotype, with increased expression of alpha-smooth muscle actin (alpha SMA) and enhanced secretion of extracellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662f6ab97d40ca1f93d69d041c1bc4d4
https://doi.org/10.1152/ajplung.00439.2017
https://doi.org/10.1152/ajplung.00439.2017
Publikováno v:
Am. J. Physiol. Lung Cell Mol. Physiol. 314, L695-L707 (2018)
Fibroblasts are thought to be the prime cell type for producing and secreting extracellular matrix (ECM) proteins in the connective tissue. The profibrotic cytokine transforming growth factor-β1 (TGF-β1) activates and transdifferentiates fibroblast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba220f30d7743b23ebe2cc139da33234
https://doi.org/10.1152/ajplung.00205.2017
https://doi.org/10.1152/ajplung.00205.2017
Publikováno v:
Am. J. Respir. Cell Mol. Biol. 52, 263-284 (2015)
Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) represent one of the most intensively studied families of growth factors in the last four decades. PDGF signaling plays an essential role in cell proliferation, differentiation, mig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fbe910912ad4413c7c77ac592d93df
https://pubmed.ncbi.nlm.nih.gov/25303647
https://pubmed.ncbi.nlm.nih.gov/25303647
Publikováno v:
American Journal of Respiratory Cell & Molecular Biology; Mar2015, Vol. 52 Issue 3, p263-284, 22p, 4 Diagrams, 3 Charts