Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nina N. Pawlowski"'
Autor:
Katja Grollich, Anja A. Kühl, Christoph Loddenkemper, Nina N. Pawlowski, Martin Zeitz, Jürgen Westermann, Maike Blessenohl, Jörg C. Hoffmann
Publikováno v:
Immunology. 128:580-588
Deficiency in gammadelta T cells aggravates colitis in animal models suggesting that gammadelta T cells have regulatory properties. Therefore, proliferation, suppression and cytokine secretion of human gammadelta T cells were determined in vitro. Hum
Autor:
Christoph Loddenkemper, Katja Grollich, Nina N. Pawlowski, Jörg C. Hoffmann, Martin Zeitz, Anja A. Kühl
Publikováno v:
International Journal of Colorectal Disease. 23:909-920
The intestinal immune system is continuously challenged by antigen without becoming dysregulated. However, injury of the mucosa by, i.e. dextran sulphate sodium causes severe inflammation in gammadelta T-cell-deficient mice. We therefore asked whethe
Autor:
Anja A. Kühl, Nina N. Pawlowski, Katja Grollich, Christoph Loddenkemper, Martin Zeitz, Jörg C. Hoffmann
Publikováno v:
Journal of Leukocyte Biology. 81:168-175
The role of gammadelta T cells in inflammatory bowel disease (IBD) is still controversial. Although gammadelta T cells induce IBD in immunodeficient animals, others suggest a protective role of gammadelta T cells. Therefore, this study was conducted
Autor:
Jörg C. Hoffmann, Sven Henschke, Martin K. Wild, Anton J. Kroesen, Nina N. Pawlowski, Martin Zeitz
Publikováno v:
International Journal of Colorectal Disease. 21:321-331
Accumulation of T lymphocytes in the gut is a hallmark of inflammatory bowel disease probably caused by insufficient T cell apoptosis. Activated peripheral T cells, or "resting" lamina propria T lymphocytes (LPLs), are highly susceptible to apoptosis
Autor:
Katja Grollich, Christoph Loddenkemper, Anja A. Kühl, Hacer Kakirman, Nina N. Pawlowski, Martin Zeitz, Oliver Liesenfeld, Jörg C. Hoffmann
Publikováno v:
Laboratory Investigation. 85:1013-1023
Increased proliferation, defective apoptosis, and cytokine dysregulation of T lymphocytes are thought to be important for the pathogenesis of inflammatory bowel disease. Since these phenomena can be corrected by alpha CD 2 mAb, we asked whether CD2 d
Autor:
Anja A, Kühl, Nina N, Pawlowski, Katja, Grollich, Maike, Blessenohl, Jürgen, Westermann, Martin, Zeitz, Christoph, Loddenkemper, Jörg C, Hoffmann
Publikováno v:
Immunology. 128(4)
Deficiency in gammadelta T cells aggravates colitis in animal models suggesting that gammadelta T cells have regulatory properties. Therefore, proliferation, suppression and cytokine secretion of human gammadelta T cells were determined in vitro. Hum
Autor:
Anja A. Kühl, Jörg C. Hoffmann, Oliver Liesenfeld, Daniela Struck, Katja Grollich, Martin Zeitz, Nina N. Pawlowski
Publikováno v:
World journal of gastroenterology. 13(31)
To investigate whether bowel inflammation and/or parasite control is altered in the absence of the T cell adhesion molecule CD2.Wildtype (WT) and CD2 deficient (CD2(-/-)) mice were infected with 100 cysts of Toxoplasma gondii (T. gondii) (ME49) by ga
Autor:
Anja A. Kühl, Christoph Loddenkemper, Markus M. Heimesaat, Stefan Dreher, Hacer Kakirman, Jörg C. Hoffmann, Philipp Cremer, Nina N. Pawlowski, Markus Janotta, Katja Grollich, Stefan Farkas, Martin Zeitz
Publikováno v:
Gastroenterology. 133(6)
Background & Aims: Neutrophils are generally thought to play an important proinflammatory role in the pathogenesis of inflammatory bowel disease. The objective of this study was to evaluate whether blocking the invasion of neutrophils by anti-L-selec
Publikováno v:
Pathobiology : journal of immunopathology, molecular and cellular biology. 70(3)
Inflammatory bowel disease (IBD) research has been performed in human in vitro studies and in in vivo studies using appropriate animal models. Such animal models allow both the examination of inflammatory processes (both early and late events) as wel
Autor:
Ulrike Erben, Joerg C. Hoffmann, Katja Grollich, Nina N. Pawlowski, Martin Zeitz, Christoph Loddenkemper, Anja A. Kuehl
Publikováno v:
Gastroenterology. 140:S-486