Výsledky vyhledávání - "Nina Molin Høyland-Kroghsbo"

Akademický článek

The great divide: rhamnolipids mediate separation between P. aeruginosa and S. aureus

Autor: Jean-Louis Bru, Summer J. Kasallis, Rendell Chang, Quantum Zhuo, Jacqueline Nguyen, Phillip Pham, Elizabeth Warren, Katrine Whiteson, Nina Molin Høyland-Kroghsbo, Dominique H. Limoli, Albert Siryaporn

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)

The interactions between bacterial species during infection can have significant impacts on pathogenesis. Pseudomonas aeruginosa and Staphylococcus aureus are opportunistic bacterial pathogens that can co-infect hosts and cause serious illness. The f

Externí odkaz: https://doaj.org/article/72165dcd17f343a5824da9315037f9b6

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Akademický článek

An Endogenous Staphylococcus aureus CRISPR-Cas System Limits Phage Proliferation and Is Efficiently Excised from the Genome as Part of the SCCmec Cassette

Autor: Kasper Mikkelsen, Janine Zara Bowring, Yong Kai Ng, Frida Svanberg Frisinger, Julie Kjærsgaard Maglegaard, Qiuchun Li, Raphael N. Sieber, Andreas Petersen, Paal Skytt Andersen, Jakob T. Rostøl, Nina Molin Høyland-Kroghsbo, Hanne Ingmer

Publikováno v: Microbiology Spectrum, Vol 11, Iss 4 (2023)

ABSTRACT CRISPR-Cas is an adaptive immune system that allows bacteria to inactivate mobile genetic elements. Approximately 50% of bacteria harbor CRISPR-Cas; however, in the human pathogen Staphylococcus aureus, CRISPR-Cas loci are less common and of

Externí odkaz: https://doaj.org/article/af56ee53f3ed4788bccc52594ef15625

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Akademický článek

Temperature, by Controlling Growth Rate, Regulates CRISPR-Cas Activity in Pseudomonas aeruginosa

Autor: Nina Molin Høyland-Kroghsbo, Katrina Arcelia Muñoz, Bonnie L. Bassler

Publikováno v: mBio, Vol 9, Iss 6 (2018)

ABSTRACT Clustered regularly interspaced short palindromic repeat (CRISPR)-associated (CRISPR-Cas) systems are adaptive defense systems that protect bacteria and archaea from invading genetic elements. In Pseudomonas aeruginosa, quorum sensing (QS) i

Externí odkaz: https://doaj.org/article/b926fdf6b8094ab89adcd9387db50d15

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Akademický článek

Loss of miR-10a activates lpo and collaborates with activated Wnt signaling in inducing intestinal neoplasia in female mice.

Autor: Gustavo Stadthagen, Disa Tehler, Nina Molin Høyland-Kroghsbo, Jiayu Wen, Anders Krogh, Klaus T Jensen, Eric Santoni-Rugiu, Lars H Engelholm, Anders H Lund

Publikováno v: PLoS Genetics, Vol 9, Iss 10, p e1003913 (2013)

miRNAs are small regulatory RNAs that, due to their considerable potential to target a wide range of mRNAs, are implicated in essentially all biological process, including cancer. miR-10a is particularly interesting considering its conserved location

Externí odkaz: https://doaj.org/article/0f9aa5d312684355b6d05c261a3f76dd

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Akademický článek

A Quorum-Sensing-Induced Bacteriophage Defense Mechanism

Autor: Nina Molin Høyland-Kroghsbo, Rasmus Baadsgaard Mærkedahl, Sine Lo Svenningsen

Publikováno v: mBio, Vol 4, Iss 1 (2013)

ABSTRACT One of the key determinants of the size, composition, structure, and development of a microbial community is the predation pressure by bacteriophages. Accordingly, bacteria have evolved a battery of antiphage defense strategies. Since mainta

Externí odkaz: https://doaj.org/article/1403ada836814c56917cd27377f61d98

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EndogenousStaphylococcus aureusCRISPR-cassystem limits phage proliferation and efficiently excises from the genome as part of the SCCmeccassette

CRISPR-Cas is an adaptive immune system that allows bacteria to inactivate mobile genetic elements. Approximately 50% of bacteria harbor CRISPR-cas, however in the human pathogenStaphylococcus aureus, CRISPR-casloci are less common and often studied

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce8613a6057e6471a8b76142ad011ac8
https://doi.org/10.1101/2023.03.19.533347

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Quorum sensing inhibits Type III-A CRISPR-Cas system activity through repressing positive regulators SarA and ArcR inStaphylococcus aureus

Autor: Yang Li, Yuanyue Tang, Xiaofei Li, Nina Molin Høyland-Kroghsbo, Hanne Ingmer, Xinan Jiao, Qiuchun Li

CRISPR-Cas is an adaptive immune system that protects prokaryotes from the invasion of foreign genetic elements. The components and immunity mechanisms of CRISPR-Cas have been extensively studied, but the regulation of this system inStaphylococcirema

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c7035c99f40e28bfaa1682be6de94fd
https://doi.org/10.1101/2023.01.17.524377

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Collaborations Between Microbes and those who Love Them

Autor: Nina Molin Høyland-Kroghsbo

Publikováno v: Høyland-Kroghsbo, N M 2023, ' Collaborations Between Microbes and those who Love Them ', Israel Journal of Chemistry, vol. 63, e202200082 . https://doi.org/10.1002/ijch.202200082

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70d455534a724172cff2d40fec2a702
https://curis.ku.dk/portal/da/publications/collaborations-between-microbes-and-those-who-love-them(c1f82d44-68c9-4cc5-9ab3-284b3188ed4c).html

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Functional Characterization of Type III-A CRISPR-Cas in a Clinical Human Methicillin-R Staphylococcus aureus Strain

Autor: Xinan Jiao, Nina Molin Høyland-Kroghsbo, Yang Li, Kasper Mikkelsen, Zhenyu Wang, Hanne Ingmer, Oleguer Lluch I Grané, Qiuchun Li, Yuanyue Tang

Publikováno v: The CRISPR Journal. 4:686-698

CRISPR with its cas genes is an adaptive immune system that protects prokaryotes against foreign genetic elements. The type III-A CRISPR-Cas system is rarely found in Staphylococcus aureus, and little is known about its function in S. aureus. Here, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba0e9ffb31461102f1ae54de80033c43
https://doi.org/10.1089/crispr.2021.0046

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The effect of Quorum sensing inhibitors on the evolution of CRISPR-based phage immunity in Pseudomonas aeruginosa

Autor: Edze R. Westra, Matthew A. W. Chisnall, Angus Buckling, Jenny M. Broniewski, Nina Molin Høyland-Kroghsbo

Publikováno v: The ISME Journal
Broniewski, J M, Chisnall, M A W, Høyland-Kroghsbo, N M, Buckling, A & Westra, E R 2021, ' The effect of Quorum sensing inhibitors on the evolution of CRISPR-based phage immunity in Pseudomonas aeruginosa ', I S M E Journal, vol. 15, pp. 2465-2473 . https://doi.org/10.1038/s41396-021-00946-6

Quorum sensing controls the expression of a wide range of important traits in the opportunistic pathogen Pseudomonas aeruginosa, including the expression of virulence genes and its CRISPR-cas immune system, which protects from bacteriophage (phage) i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c658cc3a2700a46987b187faf7d7fca
http://europepmc.org/articles/PMC8319334

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