Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nina Margherita, Poltronetti"'
Autor:
Cécile Tissot, Joseph Therriault, Peter Kunach, Andréa L Benedet, Tharick A. Pascoal, Nicholas J. Ashton, Thomas K. Karikari, Stijn Servaes, Firoza Z. Lussier, Mira Chamoun, Dana L. Tudorascu, Jenna Stevenson, Nesrine Rahmouni, Nina Margherita Poltronetti, Vanessa Pallen, Gleb Bezgin, Min Su Kang, Sulantha S. Mathotaarachchi, Yi-Ting Wang, Jaime Fernandez Arias, Pamela Cristina Lukasewicz Ferreira, João Pedro Ferrari-Souza, Eugeen Vanmechelen, Kaj Blennow, Henrik Zetterberg, Serge Gauthier, Pedro Rosa-Neto
Publikováno v:
EBioMedicine, Vol 76, Iss , Pp 103837- (2022)
Summary: Background: Tau in Alzheimer's disease (AD) is assessed via cerebrospinal fluid (CSF) and Positron emission tomography (PET). Novel methods to detect phosphorylated tau (pTau) in blood have been recently developed. We aim to investigate agre
Externí odkaz:
https://doaj.org/article/61fd198c9c7a4bc288c73fdc88da480b
Autor:
Cécile Tissot, Stijn Servaes, Firoza Z. Lussier, João Pedro Ferrari-Souza, Joseph Therriault, Pâmela C.L. Ferreira, Gleb Bezgin, Bruna Bellaver, Douglas Teixeira Leffa, Sulantha S. Mathotaarachchi, Mira Chamoun, Jenna Stevenson, Nesrine Rahmouni, Min Su Kang, Vanessa Pallen, Nina Margherita-Poltronetti, Yi-Ting Wang, Jaime Fernandez-Arias, Andrea L. Benedet, Eduardo R. Zimmer, Jean-Paul Soucy, Dana L. Tudorascu, Annie D. Cohen, Madeleine Sharp, Serge Gauthier, Gassan Massarweh, Brian Lopresti, William E. Klunk, Suzanne L. Baker, Victor L. Villemagne, Pedro Rosa-Neto, Tharick A. Pascoal
Publikováno v:
Journal of Nuclear Medicine. 64:452-459
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3978ce0e666e846e81f7ad31265a093d
https://doi.org/10.2967/jnumed.122.264434
https://doi.org/10.2967/jnumed.122.264434
Autor:
João Pedro Ferrari-Souza, Firoza Z. Lussier, Douglas T. Leffa, Joseph Therriault, Cécile Tissot, Bruna Bellaver, Pâmela C. L. Ferreira, Maura Malpetti, Yi-Ting Wang, Guilherme Povala, Andréa L. Benedet, Nicholas J. Ashton, Mira Chamoun, Stijn Servaes, Gleb Bezgin, Min Su Kang, Jenna Stevenson, Nesrine Rahmouni, Vanessa Pallen, Nina Margherita Poltronetti, John T. O’Brien, James B. Rowe, Ann D. Cohen, Oscar L. Lopez, Dana L. Tudorascu, Thomas K. Karikari, William E. Klunk, Victor L. Villemagne, Jean-Paul Soucy, Serge Gauthier, Diogo O. Souza, Henrik Zetterberg, Kaj Blennow, Eduardo R. Zimmer, Pedro Rosa-Neto, Tharick A. Pascoal
Publikováno v:
Science Advances. 9
Animal studies suggest that the apolipoprotein E ε4 ( APOE ε4) allele is a culprit of early microglial activation in Alzheimer’s disease (AD). Here, we tested the association between APOE ε4 status and microglial activation in living individuals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95c013b467329c1bbd89b2d9ffbee7a4
https://doi.org/10.1126/sciadv.ade1474
https://doi.org/10.1126/sciadv.ade1474
Autor:
Tatsuhiro Terada, Joseph Therriault, Min Su Kang, Melissa Savard, Tharick Ali Pascoal, Firoza Lussier, Cecile Tissot, Yi‐Ting Wang, Andrea Benedet, Nina Margherita Poltronetti, Julie Ottoy, Jaime Frenandez Arias, Gleb Bezgin, Takashi Matsudaira, Tomoyasu Bunai, Tomokazu Obi, Hideo Tsukada, Yasuomi Ouchi, Pedro Rosa‐Neto
Publikováno v:
European Journal of Neurology. 29:1324-1334
Abnormal mitochondrial metabolism has been described in the Alzheimer's disease (AD) brain. However, the relationship between AD pathophysiology and key mitochondrial processes remains elusive. The purpose of this study was to investigate whether mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab687b78ef6bfcf7f5db204fb515588d
https://doi.org/10.1111/ene.15246
https://doi.org/10.1111/ene.15246
Autor:
Jaime Fernández Arias, Joseph Therriault, Emilie Thomas, Firoza Z Lussier, Gleb Bezgin, Cécile Tissot, Stijn Servaes, Sulantha S Mathotaarachchi, Dorothée Schoemaker, Jenna Stevenson, Nesrine Rahmouni, Min Su Kang, Vanessa Pallen, Nina Margherita Poltronetti, Yi-Ting Wang, Peter Kunach, Mira Chamoun, Kely M Quispialaya S, Paolo Vitali, Gassan Massarweh, Serge Gauthier, Maria N Rajah, Tharick Pascoal, Pedro Rosa-Neto
Publikováno v:
Brain Communications. 5
A classical early sign of typical Alzheimer’s disease is memory decline, which has been linked to the aggregation of tau in the medial temporal lobe. Verbal delayed free recall and recognition tests have consistently probed useful to detect early m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d62982e0708ee8e8baaa5cf7c7c5ce2
https://doi.org/10.1093/braincomms/fcad146
https://doi.org/10.1093/braincomms/fcad146
Autor:
João Pedro Ferrari‐Souza, Firoza Z Lussier, Cécile Tissot, Douglas Teixeira Leffa, Pamela C.L. Ferreira, Bruna Bellaver, Wagner S. Brum, Andréa Lessa Benedet, Joseph Therriault, Yi‐Ting Wang, Mira Chamoun, Stijn Servaes, Gleb Bezgin, Min Su Kang, Jenna Stevenson, Nesrine Rahmouni, Vanessa Pallen, Nina Margherita Poltronetti, Diogo O. Souza, Serge Gauthier, Eduardo R Zimmer, Pedro Rosa‐Neto, Tharick A Pascoal
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca18066a03ca94d16825f3395ca98991
https://doi.org/10.1002/alz.065731
https://doi.org/10.1002/alz.065731
Autor:
Jaime Fernandez Arias, Joseph Therriault, Firoza Z Lussier, Tharick A Pascoal, Cécile Tissot, Yi‐Ting Wang, Gleb Bezgin, Stijn Servaes, Min Su Kang, Mira Chamoun, Jenna Stevenson, Nesrine Rahmouni, Nina Margherita Poltronetti, Peter Kunach, Julie Ottoy, Alyssa Stevenson, Sulantha Mathotaarachchi, Gassan Massarweh, Paolo Vitali, Serge Gauthier, Pedro Rosa‐Neto
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d4e08dcb122e81de5645007c1a28668
https://doi.org/10.1002/alz.067152
https://doi.org/10.1002/alz.067152
APOEε4 carriership associates with microglial activation independently of Aβ plaques and tau tangles
Autor:
João Pedro Ferrari-Souza, Firoza Z. Lussier, Douglas T. Leffa, Joseph Therriault, Cécile Tissot, Bruna Bellaver, Pâmela C. Lukasewicz Ferreira, Maura Malpetti, Yi-Ting Wang, Guilherme Povala, Andréa L. Benedet, Nicholas J. Ashton, Mira Chamoun, Stijn Servaes, Gleb Bezgin, Min Su Kang, Jenna Stevenson, Nesrine Rahmouni, Vanessa Pallen, Nina Margherita Poltronetti, John T. O’Brien, James B. Rowe, Ann D. Cohen, Oscar L. Lopez, Dana L. Tudorascu, Thomas K. Karikari, William E. Klunk, Victor L. Villemagne, Jean-Paul Soucy, Serge Gauthier, Diogo O. Souza, Henrik Zetterberg, Kaj Blennow, Eduardo R. Zimmer, Pedro Rosa-Neto, Tharick A. Pascoal
Microglial activation is an early phenomenon in Alzheimer’s disease (AD) that may occur prior to and independently of amyloid-β (Aβ) aggregation. Recent studies in transgenic animal models suggest that the apolipoprotein E ε4 (APOEε4) allele ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78c90e9151b128f8190e552b1a3a3bca
https://doi.org/10.1101/2022.07.12.22277556
https://doi.org/10.1101/2022.07.12.22277556
Performance of plasma amyloid, tau, and astrocyte biomarkers to identify cerebral AD pathophysiology
Autor:
Pâmela C. L Ferreira, Cécile Tissot, João Pedro Ferrari-Souza, Wagner S. Brum, Bruna Bellaver, Douglas T. Leffa, Joseph Therriault, Andréa L. Benedet, Firoza Z. Lussier, Mira Chamoun, Gleb Bezgin, Stijn Servaes, Jenna Stevenson, Nesrine Rahmouni, Vanessa Pallen, Min Su Kang, Nina Margherita Poltronetti, Dana L. Tudorascu, William E. Klunk, Victor L. Villemagne, Annie Cohen, Serge Gauthier, Eduardo R. Zimmer, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Thomas K. Karikari, Pedro Rosa-Neto, Tharick A. Pascoal
IntroductionPlasma amyloid-β (Aβ), phosphorylated tau (p-tau), and glial fibrillar acid protein (GFAP) can identify Alzheimer’s disease (AD) pathophysiology with high accuracy. However, comparing their performance in the same individuals remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11f286ac5439013279e7affc0e3754ef
https://doi.org/10.1101/2022.02.21.22271198
https://doi.org/10.1101/2022.02.21.22271198
Autor:
João Pedro Ferrari-Souza, Pâmela C. L. Ferreira, Bruna Bellaver, Cécile Tissot, Yi-Ting Wang, Douglas T. Leffa, Wagner S. Brum, Andréa L. Benedet, Nicholas J. Ashton, Marco Antônio De Bastiani, Andréia Rocha, Joseph Therriault, Firoza Z. Lussier, Mira Chamoun, Stijn Servaes, Gleb Bezgin, Min Su Kang, Jenna Stevenson, Nesrine Rahmouni, Vanessa Pallen, Nina Margherita Poltronetti, William E. Klunk, Dana L. Tudorascu, Ann D. Cohen, Victor L. Villemagne, Serge Gauthier, Kaj Blennow, Henrik Zetterberg, Diogo O. Souza, Thomas K. Karikari, Eduardo R. Zimmer, Pedro Rosa-Neto, Tharick A. Pascoal
Astrocytes can adopt multiple molecular phenotypes in the brain of Alzheimer’s disease (AD) patients. Here, we studied the associations of cerebrospinal fluid (CSF) glial fibrillary acidic protein (GFAP) and chitinase-3-like protein 1 (YKL-40) leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de69cb920a43b8825b8ed2f8d905c4c
https://doi.org/10.1101/2022.01.25.22269841
https://doi.org/10.1101/2022.01.25.22269841