Výsledky vyhledávání - "Nina Makowski"

A continued method performance monitoring approach for the determination of pediatric renin samples – application within a European clinical trial

Autor: S.N. de Wildt, B.B. Burckhardt, Anke Bartel, Mohsin Ali, Nina Makowski, M Feickert, I Burdman

Publikováno v: Clinical Chemistry and Laboratory Medicine, 58, 11, pp. 1847-1855
Clinical Chemistry and Laboratory Medicine, 58, 1847-1855

Background Plasma renin levels were determined in the academia-driven, EU-funded “Labeling of Enalapril from Neonates up to Adolescents” (LENA) project to evaluate its role in pediatric heart failure. Quality-controlled bioanalysis is crucial to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910a222c1bc132d93641d7be95834551
https://doi.org/10.1515/cclm-2019-1162

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Enabling insights into the maturation of the renin–angiotensin–aldosterone system in children—Development of a low-volume LC–MS assay for the simultaneous determination of aldosterone, its precursor, and main metabolite

Autor: Nina Makowski, Bjoern B. Burckhardt

Publikováno v: Steroids. 148:73-81

Introduction As part of the renin–angiotensin–aldosterone system (RAAS), aldosterone is key to the pathology of cardiovascular and renal diseases, leading to end-organ damage and cardiovascular death. Because of different aetiology and metabolism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8518b7bb1a0a7c53d0cb1ae70651fafa
https://doi.org/10.1016/j.steroids.2019.04.009

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Pharmacotherapy in paediatric heart failure: a Delphi process

Autor: Nina Makowski, Milica Bajcetic, Holger Schwender, Feras Khalil, Ida Jovanovic, Jennifer Walsh, Stephanie Läer, Michiel Dalinghaus, Saskia N. de Wildt, Cristina Castro Díez, Marijke van der Meulen

Publikováno v: Cardiology in the Young, 29(7):Pii s104795111900066, 869-876. Cambridge University Press
Cardiology in the Young, 29, 7, pp. 869-876
Cardiology in the Young, 29, 869-876

Background:Little evidence exists to support pharmacotherapeutic strategies for heart failure management in paediatrics. A recent Europe-wide survey suggests that this translates into substantial variability in clinical practice.Objective:To conduct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e329f1fbca28db515e05d7a0aea9db0d
https://doi.org/10.1017/s1047951119000660

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A comprehensive quality control system suitable for academic research: application in a pediatric study

Autor: Nina Makowski, Agnes M Ciplea, Mohsin Ali, Ilja Burdman, Anke Bartel, Bjoern B Burckhardt, Stephanie Läer, Jörg Breitkreutz, Ingrid Klingmann, Florian Lagler, Jan de Hoon, Michel Dalinghaus, Milica Bajcetic, Saskia de Wildt, Anne Keatley Clarke, Johannes Breur, Christoph Male, Laslo Ablonczy, Thomas Mir, Vladislav Vukomanovic, Milan Dukic, Ida Jovanovic, Bjoern Burckhardt, Willi Cawello, Karl Kleine, Angelika Moder, Emina Obarcanin, Peter Wagner, Jennifer Walsh, Anne van Hecken, Lucie Spatenkova, Ali Mohsin, Bojana Božić, Maja Bijelić, Agnes Ciplea, Muhammed Faisal, Samieh Farahani, Martin Feickert, Tanja Gangnus, Milica Lazic, Fabian Süssenbach, Marijke van der Meulen, Saša Popović, Miro Parezanović, Nori Smeets, Vanessa Swoboda, Dragana Bojanin, Stefan Đorđević, Jasminka Dragić, Ann-Kathrin Holle, Bosiljka Jovičić, Jovan Košutić, Gordana Kozomara, Haidara Majid, Jadranka Mitrović, Sanja Ninić, Miro Parezanovic, Vojislav Parezanovic, Andrija Pavlović, Sergej Prijić, Branislava Rebić, Igor Stefanović, Daniel Tordas, Irena Vulićević, Andjelka čeko, Marissa Herborts, Annelies Hennink, Bosiljka Kosanović, Sanja Kostic, Ljiljana Isailović, Jasmina Maksimovic, Badies Manai, Nada Martinović, Gyöngyi Máté, Miloš Perišić, Jelena Reljić, Regina Pirker, Marta Salamomovic, Claudia Schlesner, Jutta Tins, Eva Wissmann

Publikováno v: Bioanalysis, 12, 5, pp. 319-333
Bioanalysis, 12, 319-333

Item does not contain fulltext Aim: Clinical research in pediatrics is progressively initiated by academia. As the reliability of pharmacodynamic measures is closely linked to the quality of bioanalytical data, bioanalytical quality assurance is cruc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa41c6ede99bff4250575c889a10af3
https://hdl.handle.net/2066/220451

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A quality control system for ligand-binding assay of plasma renin activity: Proof-of-concept within a pharmacodynamic study

Autor: Fabian Konstantin Suessenbach, Nina Makowski, Martin Feickert, Tanja Gangnus, Jutta Tins, Bjoern Bengt Burckhardt, Stephanie Läer, Jörg Breitkreutz, Ingrid Klingmann, Florian Lagler, Jan de Hoon, Michiel Dalinghaus, Milica Bajcetic, Saskia de Wildt, Anne Keatley Clarke, Johannes Breur, Christoph Male, Laslo Ablonczy, Thomas Mir, Vladislav Vukomanovic, Milan Dukic, Ida Jovanovic, Bjoern B. Burckhardt, Willi Cawello, Karl Kleine, Angelika Moder, Emina Obarcanin, Peter Wagner, Jennifer Walsh, Anne van Hecken, Lucie Spatenkova, Mohsin Ali, Bojana Božić, Maja Bijelić Ilja Burdman, Agnes Ciplea, Muhammad Faisal, Samieh Farahani, Milica Lazic, Fabian Suessenbach, Marijke van der Meulen, Saša Popović, Miro Parezanović, Nori Smeets, Vanessa Swoboda, Dragana Bojanin, Stefan Đorđević, Jasminka Dragić, Ann-Kathrin Holle, Bosiljka Jovičić, Jovan Košutić, Gordana Kozomara, Haidara Majid, Jadranka Mitrović, Sanja Ninić, Miro Parezanovic, Vojislav Parezanovic, Andrija Pavlović, Sergej Prijić, Branislava Rebić, Igor Stefanović, Daniel Tordas, Irena Vulićević, Anke Bartels, Andjelka Čeko, Marissa Herborts, Annelies Hennink, Bosiljka Kosanović, Sanja Kostic, Ljiljana Isailović, Jasmina Maksimovic, Badies Manai, Nada Martinović, Gyöngyi Máté, Miloš Perišić, Jelena Reljić, Regina Pirker Marta Salamomovic, Claudia Schlesner, Eva Wissmann

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis, 181

Contains fulltext : 220641.pdf (Publisher’s version ) (Closed access) While the role of plasma renin activity (PRA) in heart failure has been widely studied in adults, comprehensive data on pediatric heart failure remain lacking. This drawback is i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c0479aaad26111a682409cd0b4a514
http://hdl.handle.net/2066/220641

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P34 Reliable results in continuous bioanalysis of paediatric renin samples – comprehensive quality assessment within clinical studies in children

Autor: Agnes Maria Ciplea, Nina Makowski, Haidara Majid, M Feickert, Anke Bartel, I Burdman, S Farahani, BB Burckhardt, Mohsin Ali

Publikováno v: Archives of Disease in Childhood. 104:e31.1-e31

BackgroundAs the initiator of the Renin-Angiotensin-Aldosterone-system, renin plays an essential role in the vicious circle of heart failure. Therefore, renin was determined in the investigators driven ‘Labelling of Enalapril from neonates up to ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80d03286f5a51a68079cf6589d4ca2fc
https://doi.org/10.1136/archdischild-2019-esdppp.72

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P95 Compilation of available plasma renin activity levels in the healthy and cardiac diseased paediatric population

Autor: T Gangnus, Nina Makowski, Stephanie Laeer, FK Suessenbach, I Burdman, BB Burckhardt

Publikováno v: Archives of Disease in Childhood. 104:e56.2-e57

BackgroundThe physiological and pathophysiological characteristics regarding plasma renin activity (PRA) in the context of the renin-angiotensin-aldosterone-system (RAAS) are well investigated in adults, whereas less is known in paediatric population

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::053614c25b489101476d57a30c0eb72d
https://doi.org/10.1136/archdischild-2019-esdppp.133

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P37 Reference ranges of blood NT-proBNP in paediatric heart failure and healthy controls: compilation of literature data

Autor: Nina Makowski, T Gangnus, FK Suessenbach, Stephanie Laeer, BB Burckhardt, I Burdman

Publikováno v: Archives of Disease in Childhood. 104:e32.2-e32

BackgroundN-terminal pro-brain natriuretic peptide (NT-proBNP) is a valuable biomarker for diagnosis and prognosis of heart failure in adults, included into the European Society Guidelines for heart failure (2016).1 It is also considered as a diagnos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d7d9e197215072f6ed4058512113f11
https://doi.org/10.1136/archdischild-2019-esdppp.75

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P64 Quality assessment for the continuous bioanalysis of aldosterone: application in an European paediatric study

Autor: Mohsin Ali, BB Burckhardt, Agnes Maria Ciplea, Anke Bartel, Nina Makowski, Haidara Majid, I Burdman, S Farahani

Publikováno v: Archives of Disease in Childhood. 104:e43.3-e44

BackgroundA validation is crucial to ensure the quality of an analytical method and its results. However, the validation is only a first step, further quality assessment has to be utilised to ensure high quality research. Specifications for the valid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aecd13c60600865d61f0b9948837710d
https://doi.org/10.1136/archdischild-2019-esdppp.102

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